Vol 39, No 2 (2020)
- Year: 2020
- Articles: 12
- URL: https://journals.eco-vector.com/RMMArep/issue/view/3456
- DOI: https://doi.org/10.17816/rmmar.392
Articles
THE FEATURES OF TREATMENT AND DIAGNOSTIC APPROACH, THE EVACUATION TACTICS AT THERMAL BURNS ON NAVY
Abstract
EXPERIENCE IN CREATING AN INNOVATIVE PRODUCT: STAGES FROM THE IDEA TO THE PRODUCTION AREA
Abstract
POSSIBLE STRATEGIES FOR USING MESENCHYMAL STEM CELLS TO TREAT FROSTBITE
Abstract
FEATURES OF LABORATORY DIAGNOSTIC OF COVID-19 DISEASE
Abstract
GENETIC PREDICTORS OF REGULATION OF THE ACTIVITY OF A STRESS-SYSTEM
Abstract
GENERALIZED TUBERCULOSIS IN A MILITARY PROCEEDING UNDER THE MASK OF SARCOIDOSIS. CLINICAL CASE
Abstract
DANIO RERIO (ZEBRAFISH) AS A MODEL FOR RADIOBIOLOGICAL RESEARCH
Abstract
PSYCHOLOGICAL CHARACTERISTICS OF MEDICAL PERSONNEL AND CADET (STUDENT) IN CONDITIONS ADVERSIVE EPIDEMIC SITUATION
Abstract
PROFESSOR’S S. A. SHALAEV 80TH ANNIVERSARY
Abstract
KRONSTADT NAVAL HOSPITAL IN THE REVOLUTIONARY EVENTS OF 1917-1921
Abstract
History of medicine
PROFESSOR’S S. A. SHALAEV 80TH ANNIVERSARY
Abstract
Shalaev Sergey Alekseevich (born 1939) - surgeon, doctor of medical sciences (1984), professor (1986), honored doctor of the Russian Federation (1995), colonel of medical service (1980). Head of the department of thoracic (hospital) surgery from 1988 to 1994. Priority research in the field of surgery of lung cancer, purulent-destructive diseases of the lungs and pleura, injuries and injuries of the chest and chest cavity, resuscitation and anesthesia in thoracic surgery and pulmonology (1 figure, bibliography: 8 refs).
Original articles
DANIO RERIO (ZEBRAFISH) AS A MODEL FOR RADIOBIOLOGICAL RESEARCH
Abstract
Objective: to estimate the possibility of using Danio rerio (Zebrafish) as a test system for assessing the effects of ionizing radiation using an erythrocyte micronuclei test.
Materials and methods: 6 groups of fish (n = 120) were exposed to X-rays in doses of 0, 10, 20, 30, 40, 50 Gy to calculate semi-lethal dose (LD50 / 30). 9 groups of fish (n = 27) were exposed to X-ray at doses of 0 Gy (control), 0.5 Gy, 1.0 Gy, 1.5 Gy, 2.0 Gy, 3.0 Gy, 4.0 Gy, 6,0 Gy, 8.0 Gy for constructing a dose-dependent curve of the occurrence of micronuclei in peripheral blood red blood cells.
Results: the semi-lethal dose (LD50 / 30) for Danio rerio was calculated (24.9 Gy). The frequencies of micronuclei in the erythrocytes of Danio rerio were dose-dependent. Significant data of the frequency of occurrence of micronuclei were found when fish were irradiated at doses of 4.0 Gy, 6.0 Gy and 8.0 Gy.
Conclusion: Danio rerio fish are characterized by extreme radioresistance, thereby we suggest the prospect of their use in radiobiology as a lab test system for assessing the effectiveness of factors that induce mutagenic effects of ionizing radiation.
(1 pic., 1 tab., Bibl .: source)