Vol 52, No 4 (2003)

Original Research

Immunocompetent cells in the endometrium of patients with infertility and external genital endometriosis

Kulakov V.I., Volkov N.I., Bespalova J.V.


The article reports on the results of an immunohistochemical study of the endometrium of patients with infertility and external genital endometriosis. The analysis of the dynamics of the distribution of immunocompetent cells in the endometrium of patients with infertility due to external genital endometriosis in comparison with patients with infertility of tubo-peritoneal genesis was carried out.

Journal of obstetrics and women's diseases. 2003;52(4):12-16
pages 12-16 views

The role of erythropoietin in the pathogenesis and treatment of iron deficiency anemia during pregnancy and in the postpartum period

Ailamazyan E.K., Tarasova М.A., Zaitsev А.А., Samarina А.V.


Iron deficiency anemia (IDA) is a very common pathological condition during pregnancy and the postpartum period. In the structure of hematological diseases in pregnant women, anemias account for about 90% and in most cases are iron deficient [3, 17, 19]. In the third trimester of pregnancy and in the early postpartum period, almost every woman has a latent iron deficiency, and 30–40% develop IDA [4, 15, 16, 20, 26]. According to the Ministry of Health of the Russian Federation, the frequency of IDA in Russia has increased 6.3 times over the past ten years, and in St. Petersburg - almost 2 times.

The development of anemia during pregnancy is due to an imbalance of iron in the body and is associated with its increased costs for creating a fetoplacental complex, an increase in iron metabolism and a redistribution of this trace element in favor of the fetus. Iron deficiency in the body of pregnant women and women in childbirth is associated with inadequate replacement of losses due to alimentary and mobilized iron.

Journal of obstetrics and women's diseases. 2003;52(4):17-22
pages 17-22 views

Features of adaptation of newborns with intrauterine growth retardation

Evsyukova I.I., Fomenko B.A., Andreeva А.А., Kovalchuk-Kovalevskaya O.V., Dodkhoev D.S., Kianksep А.N., Tretyakova M.B., Maslyanyuk N.A.


The morbidity, adaptation characteristics, production of melatonin and creatine kinase in newborns with intrauterine growth retardation were studied. It was found that with a symmetrical form of IUGR in newborns, there is not only a lag in growth, body weight, and the formation of postural and reflex reactions from the given gestational age, but also pronounced multiple organ failure, which significantly complicates their postnatal adaptation and, probably, determines a high frequency somatic pathology and disorders of psychomotor development in the following months of life. Children who have a lag in growth and body weight combined with a delay in the formation of postural and reflex reactions as a result of intrauterine infection and placental insufficiency of infectious genesis need therapy aimed at restoring and compensating for the impaired functions of the central nervous system and other functional systems of the body.

Journal of obstetrics and women's diseases. 2003;52(4):23-27
pages 23-27 views

Activity of the brain isoenzyme creatine kinase in newborns with intrauterine growth retardation

Dodkhoev D.S., Evsyukova I.I., Tumasova Z.N., Harutyunyan А.V.


The CK-BB activity in neonates with intrauterine growth retardation (IUGR) was investi-gated and the results were compared to their clinical condition in early neonatal period. The re-sults of the study have shown that the CK-BB activity was increased in neonates with symmetric IUGR and in the presence of chronic placental insufficiency of infectious genesis.

Journal of obstetrics and women's diseases. 2003;52(4):28-32
pages 28-32 views

Procurement of autoplasma and autoplasma transfusion in the surgical treatment of gynecological patients

Bugaev A.A., Tsvelev Y.V., Kaleko S.P.


The article deals with the issues of preoperative preparation and use of autologous plasma for infusion and transfusion support of planned gynecological operations.

Journal of obstetrics and women's diseases. 2003;52(4):33-37
pages 33-37 views

The state of the endocrine system in patients with acne vulgaris. Hormonal correction methods

Samtsov A.V., Guryev V.N., Beskrovny S.V.


We analized the dates of investigations, concerning clinical and hormone status of 73 patients with acne vulgaris. It was revealed the reliable positive correlative connection between the type of seborrhea, the level of intensity of clinical picture and the level of serum progestogen, not depending from the age and constitution. The main factor in pathogenesis of acne vulgaris is the disturbances of progestogen production in the second phase of the menstrual cycle. This disturbance determine the type of seborrhea and the weight of clinical picture. The complementary factor in the development of seborrhea in the hyperfunction of androgens. We recommend the revealed pattern to use in choosing the correction patients hormone phone.

Journal of obstetrics and women's diseases. 2003;52(4):38-43
pages 38-43 views

Features of cardiointervalogram and the state of central hemodynamics in newborns who underwent acute hypoxia

Evsyukova I.I., .Fedorova М.V.


The features of the cardiointervalogram and the state of central hemodynamics were studied.

in newborns who have undergone acute hypoxia. It was found that the increase in vascular tone and centralization of blood circulation occurring in conditions of acute intrapartum hypoxia persist in the first hours and days of a child's life. An adequate circulatory regime is ensured by the involvement of various mechanisms of regulation of the activity of the cardiovascular system, which depends on the severity of the transferred hypoxia.

Journal of obstetrics and women's diseases. 2003;52(4):44-48
pages 44-48 views

Modification of cesarean section in abdominal delivery

Abramchenko V.V.


Modification of cesarean section in abdominal delivery including three main moments of operation is presented: peculiarities of abdominal cavity opening using the lower transversal incision bdominal cavity opening and peculiarities of uterine suture appliance without uterine suture coverage with visceral peritoneum and with no parietal peritoneum suture appliance

Journal of obstetrics and women's diseases. 2003;52(4):49-54
pages 49-54 views

Experience of Femoston Treatment in Perimenopausal Women Receiving Oral Corticosteroid Therapy

Dreval A.V., Marchenkova L.A., Polyakova E.Y., Kryukova I.V., Tishenina R.S., Gasparyan N.D., Grigorieva D.V., Koroleva A.V.


Chronic oral corticosteroid therapy, which is widely used for the treatment of bronchial asthma, dermatological, rheumatic diseases, systemic diseases of the connective tissue, etc., is often a psychological obstacle to the appointment of hormone replacement therapy (HRT) for women in menopause. At the same time, the appointment of estrogenic drugs for this category of patients in some cases is necessary, since by reducing climacteric symptoms, stopping urogenital disorders and increasing the level of bone mass, HRT can significantly improve the quality of life.

Journal of obstetrics and women's diseases. 2003;52(4):55-59
pages 55-59 views


Transcervical recanalization of fallopian tubes: problems and development prospects

Bezhenar V.F., Lyatoshinskaya P.V., Kira E.F., Zhemchuzhina T.Y.


In recent years many methods of transcervical cannulation of the proximall fallopian tube have been developed and reported in the literature. The purposes of this article is to review these techniques and their potential uses in modem practise.

Journal of obstetrics and women's diseases. 2003;52(4):72-76
pages 72-76 views


Anniversary of Professor Lydia Alekseevna Samorodinova


A wise doctor, an excellent clinician, professor, doctor of medical sciences, honored worker of science of the Republic of Karelia Lidiya Alekseevna has walked more than 50 years in medicine and is widely known in scientific circles. She graduated from the Samarkand Medical Institute named after I. Academician I.P. Pavlova. Then she worked for some time as an obstetrician-gynecologist in Uzbekistan. Further training took place at the Leningrad State Institute for Advanced Training of Doctors: clinical residency, postgraduate studies, worked as an assistant and associate professor of the Department of Obstetrics and Gynecology of the Leningrad State Pedagogical University. Lidia Alekseevna Samorodinova is a student of Professor A.E. Mandelstam.

Journal of obstetrics and women's diseases. 2003;52(4):1-1
pages 1-1 views

Current public health problems

Molecular neuroimmunoendocrinology: role and significance in the regulation of reproductive function

Ailamazyan E.K., Kvetnoy I.M.


The review paper is devoted to analysis of current molecular biological investigations, which testify on the molecular chemical unity of the signaling mechanisms into three classical regulatory systems-nervous, endocrine and immune ones. This biological general phenomenon allows to create a new special field of biomedicine-neuroimmunoendocrinology, which studies the structural-functional basis and molecular unity of neuroimmunoendocrine regulation of homeostasis in norm and pathology. The special attention pays on the presence of nervous, endocrine and immune cells in the reproductive system, which produce hormonal substances (regulatory peptides, biogenic amines, and related molecules) in situ inside endometrium, placenta, mammary glands. The role of these molecules in the mechanisms of reproduction is discussed.

Journal of obstetrics and women's diseases. 2003;52(4):4-11
pages 4-11 views


Pathogenetic criteria for the diagnosis, treatment and prevention of arterial hypertension during pregnancy

Arzhanova O.N., Osipova N.A.


This review is devoted to questions of pathogenesis, clinics, treatment and prophylaxis of hypertension in pregnancy. Antihypertensive agent choice is pathogenetically grounded.

Journal of obstetrics and women's diseases. 2003;52(4):60-67
pages 60-67 views


Pregnancy and delivery in patients with hepatolenticular degeneration

Vakharlovsky V.G., Lagkueva F.K., Kusova S.O., Tzidaeva T.I.


Data of pregnancy course and delivery in 3 patients with hepatolenticular degeneration (GLD) — a rare disease of autosomal recessive inheritance pattern are presented. In one case GLD was diagnosed prior pregnancy and treatment with cuprenil was continued during pregnancy. No progressive GLD clinical symptoms were observed. However pregnancy and delivery appeared to provoke GLD typical manifestations in other two patients. They have not got specific treatment with cuprenil during pregnancy as disease was diagnosed only after delivery.

Deliveries in patients with GLD were successful and the newborns were healthy. No evidence of cuprenil teratogenic effect on fetus was revealed in the first case. This GLD is not contraindication for successful pregnancy but it is necessary to use cuprenil for prevention of disease exacerbation.

Journal of obstetrics and women's diseases. 2003;52(4):68-71
pages 68-71 views

History page

The role of Nikolai Ivanovich Pirogov in the development of domestic obstetrics and gynecology

Tsvelev Y.V.


The multifaceted activities of the largest Russian surgeon N.I. Pirogova had a huge impact on the formation of the St. Petersburg obstetric and gynecological school and, in general, on the development of Russian gynecology. A.M. Geselevich and E.I. Smirnov rightly point out that the words “multifaceted activity” “precisely in relation to N.I. Pirogov ... very accurately determine the features of his work. He did not walk along the indicated corridor of one topic, even one specialty. He posed questions broadly and comprehensively resolved them, capturing neighboring specialties with the help of various scientific methods. No wonder he said that the sciences do not just border on each other, but mutually penetrate each other."

Journal of obstetrics and women's diseases. 2003;52(4):72-76
pages 72-76 views

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