Vol 52, No 4 (2003)

In recent years many methods of transcervical cannulation of the proximall fallopian tube have been developed and reported in the literature. The purposes of this article is to review these techniques and their potential uses in modem practise.

The article reports on the results of an immunohistochemical study of the endometrium of patients with infertility and external genital endometriosis. The analysis of the dynamics of the distribution of immunocompetent cells in the endometrium of patients with infertility due to external genital endometriosis in comparison with patients with infertility of tubo-peritoneal genesis was carried out.

The morbidity, adaptation characteristics, production of melatonin and creatine kinase in newborns with intrauterine growth retardation were studied. It was found that with a symmetrical form of IUGR in newborns, there is not only a lag in growth, body weight, and the formation of postural and reflex reactions from the given gestational age, but also pronounced multiple organ failure, which significantly complicates their postnatal adaptation and, probably, determines a high frequency somatic pathology and disorders of psychomotor development in the following months of life. Children who have a lag in growth and body weight combined with a delay in the formation of postural and reflex reactions as a result of intrauterine infection and placental insufficiency of infectious genesis need therapy aimed at restoring and compensating for the impaired functions of the central nervous system and other functional systems of the body.

The article deals with the issues of preoperative preparation and use of autologous plasma for infusion and transfusion support of planned gynecological operations.

The features of the cardiointervalogram and the state of central hemodynamics were studied.

in newborns who have undergone acute hypoxia. It was found that the increase in vascular tone and centralization of blood circulation occurring in conditions of acute intrapartum hypoxia persist in the first hours and days of a child's life. An adequate circulatory regime is ensured by the involvement of various mechanisms of regulation of the activity of the cardiovascular system, which depends on the severity of the transferred hypoxia.

Chronic oral corticosteroid therapy, which is widely used for the treatment of bronchial asthma, dermatological, rheumatic diseases, systemic diseases of the connective tissue, etc., is often a psychological obstacle to the appointment of hormone replacement therapy (HRT) for women in menopause. At the same time, the appointment of estrogenic drugs for this category of patients in some cases is necessary, since by reducing climacteric symptoms, stopping urogenital disorders and increasing the level of bone mass, HRT can significantly improve the quality of life.

A wise doctor, an excellent clinician, professor, doctor of medical sciences, honored worker of science of the Republic of Karelia Lidiya Alekseevna has walked more than 50 years in medicine and is widely known in scientific circles. She graduated from the Samarkand Medical Institute named after I. Academician I.P. Pavlova. Then she worked for some time as an obstetrician-gynecologist in Uzbekistan. Further training took place at the Leningrad State Institute for Advanced Training of Doctors: clinical residency, postgraduate studies, worked as an assistant and associate professor of the Department of Obstetrics and Gynecology of the Leningrad State Pedagogical University. Lidia Alekseevna Samorodinova is a student of Professor A.E. Mandelstam.

The review paper is devoted to analysis of current molecular biological investigations, which testify on the molecular chemical unity of the signaling mechanisms into three classical regulatory systems-nervous, endocrine and immune ones. This biological general phenomenon allows to create a new special field of biomedicine-neuroimmunoendocrinology, which studies the structural-functional basis and molecular unity of neuroimmunoendocrine regulation of homeostasis in norm and pathology. The special attention pays on the presence of nervous, endocrine and immune cells in the reproductive system, which produce hormonal substances (regulatory peptides, biogenic amines, and related molecules) in situ inside endometrium, placenta, mammary glands. The role of these molecules in the mechanisms of reproduction is discussed.

This review is devoted to questions of pathogenesis, clinics, treatment and prophylaxis of hypertension in pregnancy. Antihypertensive agent choice is pathogenetically grounded.

Data of pregnancy course and delivery in 3 patients with hepatolenticular degeneration (GLD) — a rare disease of autosomal recessive inheritance pattern are presented. In one case GLD was diagnosed prior pregnancy and treatment with cuprenil was continued during pregnancy. No progressive GLD clinical symptoms were observed. However pregnancy and delivery appeared to provoke GLD typical manifestations in other two patients. They have not got specific treatment with cuprenil during pregnancy as disease was diagnosed only after delivery.

Deliveries in patients with GLD were successful and the newborns were healthy. No evidence of cuprenil teratogenic effect on fetus was revealed in the first case. This GLD is not contraindication for successful pregnancy but it is necessary to use cuprenil for prevention of disease exacerbation.

The multifaceted activities of the largest Russian surgeon N.I. Pirogova had a huge impact on the formation of the St. Petersburg obstetric and gynecological school and, in general, on the development of Russian gynecology. A.M. Geselevich and E.I. Smirnov rightly point out that the words “multifaceted activity” “precisely in relation to N.I. Pirogov ... very accurately determine the features of his work. He did not walk along the indicated corridor of one topic, even one specialty. He posed questions broadly and comprehensively resolved them, capturing neighboring specialties with the help of various scientific methods. No wonder he said that the sciences do not just border on each other, but mutually penetrate each other."