Influence of certain factors on adherence to treatment in glaucoma patients in clinical practice

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Abstract

BACKGROUND: Up to 80% of patients do not comply with the treatment regimen, and this leads to the progression of the disease.

AIM: The aim of this study is the analysis of adherence to treatment based on a questionnaire survey of glaucoma patients.

MATERIALS AND METHODS: 139 patients with glaucoma were questioned. The mean age was 67.19 ± 0.84 years, 63.3% were women, 36.7% were men. 73.4% were city residents, 26.6% — village residents. 26% were diagnosed less than a year before, 34.5% — 1–5 years before, 39.5% — 5 years or more before. 47.5% received only medical therapy, the rest had a history of surgery as well. Statistical processing of the obtained results was carried out using the standard statistical analysis software package SPSS Statistics 16.0. The parameters with a normal distribution were presented as M ± m, where M is the mean value, m is the standard error of the mean.

RESULTS: On average, patients received 2.1 ± 0.08 molecules in 1.64 ± 0.06 vials. 48% of patients did not observe the frequency of visits to the ophthalmologist. Violation of adherence was present in 40.5% of cases, the main reason was forgetfulness (51%), 24.5% did not buy the medication on time, discomfort on instillation was reported in 7% of cases, systemic side effects — in 3.5%, other reasons — in 14%. Adherence does not depend on the duration of glaucoma, the number of vials, the place of residence. Contraindications to the prescription of β-blockers were present in 30% of cases.

CONCLUSIONS: The study has confirmed that nearly half of patients are non-adherent to treatment due to forgetfulness.

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About the authors

Alexey V. Malyshev

Professor S.V. Ochapovsky Regional Clinical Hospital No. 1; Maykop State Technological University

Email: mavr189@narod.ru
ORCID iD: 0000-0002-1448-9690

MD, Dr. Sci. (Med.), head of the ophthalmology Department of Scientific Research Institution; chief ophthalmologist of the Ministry of Health of the Krasnodar Territory; head of the ophthalmology Department; professor of the Ophthalmology Department; corresponding member of RANH

Russian Federation, Krasnodar; Maikop, Republic of Adygea

Anastasiya S. Apostolova

Vision Care Clinic “3Z”

Author for correspondence.
Email: apostolovan@mail.ru
ORCID iD: 0009-0006-3177-4342

MD, Cand. Sci. (Med.), ophthalmologist, ophthalmologist of diagnostic Department

Russian Federation, Krasnodar

Aleksey A. Sergienko

Maykop State Technological University; Children’s Regional Clinical Hospital, Krasnodar

Email: eyesurg@mail.ru
ORCID iD: 0000-0002-0285-4080

MD, Cand. Sci. (Med.), ophthalmologist; assistant professor

Russian Federation, Maikop, Republic of Adygea; Krasnodar

Adam F. Teshev

Maykop State Technological University; Adygean Republican Clinical Hospital

Email: adam.teshev@gmail.com
ORCID iD: 0009-0002-2434-7538

ophthalmologist, head of the Ophthalmology Department; assistant; chief ophthalmologist of the Ministry of Health of the Republic of Adygea

Russian Federation, Maikop, Republic of Adygea; Maikop, Republic of Adygea

Garry Y. Karapetov

Professor S.V. Ochapovsky Regional Clinical Hospital No. 1; Maykop State Technological University

Email: garry.karapetov@gmail.com
ORCID iD: 0000-0002-1511-1219

MD, Cand. Sci. (Med.), ophthalmologist; assistant professor

Russian Federation, Krasnodar; Maikop, Republic of Adygea

Marina K. Ashhamahova

Maykop State Technological University; Adygean Republican Clinical Hospital

Email: mashkhamakhova@gmail.ru
ORCID iD: 0009-0000-0838-2013

ophthalmologist; assistant

Russian Federation, Maikop, Republic of Adygea; Maikop, Republic of Adygea

Umar I. Midaev

Maykop State Technological University; Adygean Republican Clinical Hospital

Email: Umarmidaev@mail.ru
ORCID iD: 0009-0006-7813-211X

ophthalmologist; assistant

Russian Federation, Maikop, Republic of Adygea; Maikop, Republic of Adygea

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Supplementary files

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2. Fig. 1. Characteristics of laser and surgical treatment in the group of interviewed patients. АГО — antiglaucoma surgery, ФЭК — phacoemulsification, лазер + АГО + ФЭК — combined therapy, including combinations of laser treatment, glaucoma surgery and phacoemulsification, лазер + ФЭК — combination therapy, including combinations of laser treatment and phacoemulsification, лазер + АГО — combination therapy, including a combination of laser treatment and glaucoma surgery

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3. Fig. 2. Incidence of non-adherence among patients depending on the duration of treatment

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