Vol 22, No 4 (2014)


Dynamics of tissue and ultrastructural changes in the embryonic heart of the chick embryo

Goodlett T.A., Tverdokhleb I.V.


The analysis and comparison of histostructural and ultrastructural features of systole and diastole of the chick embryo heart at 29-46th stages on Hamburger, Hamilton were carried out. The main differences between the chambers of the embryonic heart by the nature of developmental dynamics of systolic and diastolic gradients, shows geometrical transformation of the walls of the chambers to reduce, described the features of the ultrastructure of sarcomeres, depending on the location of cardiomyocytes.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):7-14
pages 7-14 views

Significance of immunohistochemistry method for diagnosing of stomach tumors

Shponka I.S., Poslavskaya A.V., Yakovenko V.R.


The article is dedicated to the diagnosis of malignant tumors of the stomach, analyzing divergences of diagnoses after routine morphological researches and immunomorphological methods with monoclonal antibodies using, assessment of proliferative activity of different groups of tumors of this localization. Our investigation demonstrated that in the group of gastric tumors mistaken primary diagnoses were identified in 33 of 62 cases (53.2%). Proliferative score estimation is too important to determine the potential for malignancy of gastrointestinal stromal tumors and the degree of differentiation of neuroendocrine cancers.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):15-21
pages 15-21 views

Operational research methodology material in ampullary carcinoma

Paklina O.V., Setdikova G.R., Shabunin A.V., Bedin V.V., Tavobilov M.M.


Indispensable key to successful diagnosis and treatment of cancer, including ampullary carcinoma is operating properly cut material for further histological examination. In this paper we present a modern algorithm for morphological study remote organocomplexes, which is designed to achieve the maximum objective morphological data at ampullary carcinomas.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):22-28
pages 22-28 views

Histological interpretation severity of dysplasia of connective tissue in clinical practice

Uhov U.I., Sobennikov I.S., Kotans S.Y., Cherenkov A.A.


In the article we make histological examination of the severity of dysplasia of connective tissue on the example of a microscopic examination of the aponeurosis of the external oblique abdominal muscles in patients with inguinal hernia and definition changes depending on the severity of the identified connective tissue dysplasia, defined clinically.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):29-34
pages 29-34 views

Modern clinical and morphological approach to early gastric cancer

Mikhaleva L.M., Birukov A.E., Plahov R.V.


The article presents the results of histological examination of early gastric cancer, endoscopic submucosal remote resection. An algorithm for the morphological study: methods of histological, histochemical and immunohistochemical processing tissue samples, understands the sequence of morphological analysis with findings and conclusions on the effectiveness of endoscopic surgery.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):35-41
pages 35-41 views

Modeling of severe hyperhomocysteinemia in rats

Medvedev D.V., Zvyagina V.I., Fomina M.A.


To date it’s proved that the elevated homocysteine levels in the blood is an independent risk factor for a number of diseases. The animal model of rare severe form of hyperhomocysteinemia may be necessary to study aspects of homocysteine participation in damage of organs and tissues in various diseases because the effects of this pathogenetic factor will be most pronounced in such conditions. This article describes a technique for modeling in male Wistar rats a severe form of hyperhomocysteinemia by a three-week intragastric administration of methionine suspension with the addition of this amino acid in the drinking water.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):42-46
pages 42-46 views

Heart beat regulation during load test

Pokhachevsky A.L., Lapkin M.M.


Ingenious methods of cardiac rhythmgram analysis (CRG) during a load testing are used to study the heart beat (HB) and its regulation. As a result of the CRG cluster analysis of a mixed youth population: 272 persons of 17±2 years old 3 clusters are determined differing by the mixed endurance level. It is established that the latter is the basis of the activity of the autonomic (vegetative) nervous system that determines the recovery rate, as well as the HB variability up to its abnormalities. Vegetative regulation improvement within endurance training reduces the possibility of HB abnormalities by changing the value of their onset from the vegetative dystonia marker to the physical exertion and overtraining predictor. We have determined the possibility for the further study of the heart beat and its regulation with the purpose of early detection of the exercise learning by an organism and preventive measures against overload and overtraining effects.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):47-53
pages 47-53 views

The ifluens of new oxypyridine derivative on the development of toxic hepatitis

Klimkina E.I.


In conditions of experimental toxic lesion of the liver, hepatoprotective effect of the original chemical compound 2,6-dimethyl-3-oxypyridine adamantane carboxylate has been investigated. It has been shown that this compound effectively reduces the activity of liver enzymes (aspartic and alanine transaminases, lactate dehydrogenase), the content of total bilirubin and activity of free radical oxidation initiated by CCl 4 intoxication. The protective action of the substance on the liver function has been confirmed morphologically.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):54-60
pages 54-60 views

Patient evaluation of general practitioners as a tool to improve the quality of primary health care

Odrinskiy V.A.


In the experiment, on a model of acute carrageenin-induced inflammation of rat’s paw, changes in size of the affected limbs (paw edema), parameters of leukogram and activity of free radical oxidation were registered. The anti-inflammatory effect of antihypoxants (amtizol, hesperidin, hypoxen, metaprot) was investigated. It has been shown that hypoxen and metaprot 50 mg/kg have weak anti-inflammatory activity, but potentiate the effect of nonsteroidal anti-inflammatory drugs. At simultaneous enteral administration of hypoxen and metaprot with acetylsalicylic acid or diclofenac, evident anti-inflammatory effect was marked, that was manifested by significant reduction in registered inflammation symptoms.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):61-67
pages 61-67 views

Patient evaluation of general practitioners as a tool to improve the quality of primary health care

Odrinskiy V.A.


The analysis of patient satisfaction (n = 424) of the work of general practitioners and health care institutions at the primary health care level with the use of standardized EUROPEP questionnaires was carried out in Ukraine. The results show lower evaluation by patients of Ukrainian doctors activity and primary healthcare institutions on comparison with European data. For improve this situation need to implement organizational and educational activities.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):68-73
pages 68-73 views

Medical and social aspects of reproductive image formation and behavior of adolescent girls of Kyrgyz Republik

Poltava N.V.


The analysis of the survey of 1016 adolescent girls living in Bishkek, Kara-Kol, Jalalabad, we found that in Bishkek 79,1% of adolescent girls living with one of the parents, that leads to earlier adulthood. In Jalalabad girls up to 18 years more likely lives in a civil marriage. In 95,4% teenagers take money from their parents. In Bishkek, girls were significantly more likely to buy cigarettes. There is no trust relations between teens and teachers. And modern teenage girls do not want to make judgment on their parents' secrets about reproductive behavior.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):74-78
pages 74-78 views

Hydrochemical status of surface waters the city of Ryazan

Podol S.R., Popova Z.I.


Defined hydrochemical parameters of water quality urban water bodies of the city of Ryazan, the estimation of priority pollutants in river water. They are the ammonium nitrogen, nitrite nitrogen and organic matter. Best hydrochemical parameters among the studied objects have Borkowska career, the worst - the river Trubezh. It is important that the content of petroleum products, chlorine and heavy metals (zinc, copper and lead) in all objects below the exposure limits. The total hardness of water is generally below the exposure limits. The primary measure to improve water quality can be considered as the clearing and shores. This will increase the volume of water in the river, will accelerate its purification from impurities, respectively, and will improve water quality.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):79-83
pages 79-83 views

Obstetric and gynecological care in the Ryazan province in the late 18th -early 19th centuries

Kotova T.A.


The conditions of obstetric care to the population of Ryazan province in the late 18th - early 19th century was analyzed.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):84-87
pages 84-87 views

Endothelial function in patients with diabetes mellitus type 2 with arterial hypertension in good compensation of hyperglycemia

Pertseva N.O.


The purpose of this study was to quantify markers of endothelial function in patients with diabetes mellitus type 2 with arterial hypertension in good compensation of hyperglycemia and determining their relation to hemodynamics, renal function and lipid profile. The analysis showed that with good compensation of hyperglycemia endothelial dysfunction is formed before the appearance of clinical and laboratory signs of renal dysfunction and dyslipidemic disorders, accompanied by significant increase in the concentration of endothelin-1 (more than 4 times) and nearly 3-fold increase in the content of von Willebrand factor and thrombomodulin compared with the control group.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):88-92
pages 88-92 views

The comparative characteristic clinical-psychological features of adolescent patients with mild mental retardation, depending on the form of the stay

Afonina A.K., Volodin B.Y.


The article presents the results of studying clinical-psychological features 120 adolescents with mild mental retardation in age from 12 to 18 years old with different forms of the stay (boarding school or family). In the study, they were revealed significant differences in the clinical picture, self-esteem and satisfaction basic needs.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):93-96
pages 93-96 views

Social and demographic characteristics of female adolescents with alcohol addictive behavior

Muzhichenko V.A., Kirpichenko A.A., Kopytov A.V.


The authors have reviewed and identified most typical social and demographic characteristics of 14-18 year-old female adolescents from the Republic of Belarus who have had alcohol addicted behavior issues. Major social patterns associated with alcohol-addictive behavior have been identified and a social model of risk prediction has been developed for this group of patients. The findings may be useful for development of efficient targeted preventive arrangements.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):97-103
pages 97-103 views

Features of the factor structure of the quality of life of women with chronic diseases neurological and women undergoing surgery for pelvic prolapse

Molostvova G.V., Vasina I.V., Filimonov V.B., Vasin R.V.


In the article the peculiarities of the quality of life in neurological patients with chronic vascular diseases of the brain, chronic vertebral pathology and patients undergoing surgery for pelvic prolapse. It is shown that the structure of the quality of life of patients with neurological profile, includes the factors of emotional character and illustrate the response of patients to the chronic nature of the disease. The structure of the quality of life of the patients patients flatter associated, intense, illustrates the pronounced state of adaptation to life in the postoperative period. Suggested tactics of providing medical care to patients with different types of manifestations of the features of quality of life.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):104-111
pages 104-111 views

The comparative characteristic of open and chemical desympathization lumbar ganglia when recurrent ischemia after reconstructive operations on the arteries of the lower extremities

Staroverov I.N., Lonchakova O.M.


A comparison of efficiency of open and chemical desympathization lumbar ganglia in patients with recurrent ischemia of lower extremities after reconstructive surgeries. Lumbar sympathectomy was used in addition to reconstructive surgery on vessels in 43 patients, chemical destruction of sympathetic ganglia 26 patients with distal type lesions of the arteries of the legs after 4-8 days after the arterial reconstruction in the lower limbs. It is revealed, that alternative to traditional lumbar sympathectomy is a minimally invasive technique of chemical destruction of the lumbar sympathetic ganglia performed under the control of the spiral computer tomography. It has comparable efficacy compared with open interference in both the immediate and long-term care.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):112-119
pages 112-119 views

Quality of life in patients after total cement or cementless hip arthroplasty

Fedoseev A.V., Litvinov A.A., Chekushin A.A., Filonenko P.S., Al Mansour A.Y., Yurchikova E.E.


In this article, the authors compared the quality of life of patients after total hip arthroplasty with cementless (group 1) and cement (group 2) fixation of prosthetic components. Obtained similar data in both groups. The authors recommend cementless total hip arthroplasty for fractures of the femoral neck as an alternative to cement fixation method in terms of osteoporosis.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):120-123
pages 120-123 views

Changes in the hemostasis in patients with acute intestinal obstruction

Muraviev S.Y., Fedoseev A.V., Budarev V.N., Amahanov A.K., Allniazi A.E.


Acute intestinal obstruction is accompanied by changes in the hemostatic system. These changes are the deeper, the higher the degree of enteral insufficiency syndrome, concomitant obstruction. Orientation of the hemostasis shifts also depends on the severity of the syndrome. At the same time, the attempt to confirm statistically the correlation between hemostasis shifts and the severity of the enteral insufficiency syndrome failed. Consequently, the link between hemostasis shifts and processes in the intestine in patients with acute intestinal obstruction is indirect.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):124-128
pages 124-128 views

Organization of dental care residents of remote district of Ryazan area through outreach work in GBU PO "Dental polyclinic № 1»

Peshkov M.V., Peshkov V.A., Gurevich K.G.


One of the main tasks of the dental service is the maximum coverage of sanitation and preventive inspections of the population. National Population Census (2010) and the national epidemiological survey of dental population (2007-2008) showed 100% prevalence of dental caries in persons over 65 years, and nearly a third of the population (26,3%) live in the Russian countryside. To solve the problem of providing dental care to residents of remote areas where it is absent, organized a mobile dental office.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):129-133
pages 129-133 views

Innovative technologies in the diagnostics and rehabilitation treatment of patients with essential hypertension

Sokolov A.V., Svintsova S.E., Artyomova N.M.


The work presents the rational use of the indicators of functional reserves for objective assessment of clinical and functional state and treatment outcomes among patients with hypertension stage 2, grade 1-2 on the sanatorium stage. In the study involving 40 patients demonstrated that the use of low-frequency field generated by the apparatus “Hivamat” - 200 improves the results of complex sanatorium treatment of these patients and in particular allows to achieve more rapid regression of clinical manifestations of the disease and more pronounced increase of functional reserves.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):134-137
pages 134-137 views

The modern concepts problems of liver failure in surgery

Natalskiy A.A., Tarasenko S.V., Zaytsev O.V., Peskov O.D.


The problem of liver failure in patients with obstructive jaundice from the standpoint of modern ethiopathogenesis is viewed in the article. A review of the main actual classifications of liver failure was made. The original classification of liver failure in the syndrome of obstructive jaundice is presented by authors.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):138-147
pages 138-147 views

Computer users syndrome: psychometric methods in it complex investigation

Akhmadeev R.R., Timerbulatov I.F., Yuldashev V.L., Bakirov L.R.


The article contains a survery of tests and questionnaries dealing with the following: psychometric investigation of the main aspects of computer user syndrome (CUS), visual fatigue; the nature and intensity of computer addiction, the basic parameters of computer users' mental health. The methods of the flexible battery is of special attention concerning its use within CUS research.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):148-154
pages 148-154 views

On the concept of extreme

Kharitonov V.I.


The paper deals with the theoretical and practical aspects of modern problems with extreme positions and the use of the conceptual apparatus of the quantitative component of the problem. It is noted that to date there is no single point of view on the concept of "extreme" and his close concepts and definitions. It is shown that there should be a universal approach to the problem of the unity of which must be expressed through the rationale of quantitative characteristics of existing factors and performance responses of the body.
I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):155-160
pages 155-160 views

Shvalb Pavel Grigirievich

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I.P. Pavlov Russian Medical Biological Herald. 2014;22(4):161-161
pages 161-161 views

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