Vol 21, No 3 (2013)

Articles
MORPHOLOGY OF THE INNER RELIEF OF CHICK EMBRYONIC VENTRICULAR MYOCARDIUM AT 6-8 DAY INCUBATION
Goodlett T.A., Tverdokhleb I.V.
Abstract
Aim of this work was to create three-dimensional computer models of сhick embryonic heart at 6-8 day incubation followed by a comparative assessment of ventricular inner relief. In the present study, we reconstructed and morphometrically analyzed the heart staged chick embryos with the aid of computer software and compared their structures for the further assay. We show that development of the inner relief is implemented in different ways in left and right ventricles.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):8-13
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THE MORPHOLOGICAL FEATURES OF HUMAN HEPATOCYTES IN EARLY PERIODS OF ONTOGENESIS
Ponomarev B.L., Obuhova L.E., Vysoski U.A., Barsukova N.I., Cherdantseva T.M.
Abstract
The developmental features of liver of human embryos and featuses during early ontogenesis are the subject of electron microscopy study. The changes in hepatocytes ratio of different differentiation stages during late periods of embryogenesis and early periods of fetogenesis are identified. The formation of cytoplasmic organelles and changes of nucleo-cytoplasmic ratio of liver were are observed.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):14-22
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MORPHOLOGICAL CHANGES OF THE TRACHEA, BRONCHI AND LUNGS OF MICE WITH LONG EXPOSURE OF CHEMICALS PRESENT IN THE AIRSPACE OF MANNED SPACECRAFT
Oganesyan M.V., Ponomarenko E.A.
Abstract
It was conducted the morphological study of chronic exposure MPC of chemicals (acetone, acetaldehyde, ethanol) of airspace of the spacecraft on the trachea, bronchi and lungs within 70 days in male mice line of F1 (CBA x C57Bl6). At morphometric study at experimental group of mice are revealed foci of fibrosis and hyperplasia of lymphoid tissue in the wall of the trachea and bronchi, in the lungs are marked elevation of lymphoid accumulations in the wall of the main and lobar bronchi and around blood vessels. The mechanisms of development of pathological changes in the respiratory system under the influence of small doses of chemicals are discussed.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):23-27
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GRAN INFORMATION SYSTEM OF ORGANIZATION OF MENTAL BRAIN
Sudakov K.V.
Abstract
In the article the information processes involved in the activities of the functional systems of the body. Formulated ideas about the information needs and their equivalents satisfaction. It is shown that the evaluation of information in the brain is on the morphological and functional architectonic acceptors results of the action functional systems. Acceptors on the results of the action are built sistemokvants information that admission to them afferent feedback from behavioral and autonomic sistemokvants, monitor their effectiveness. The dominant motivation, situational and launchers (conditioned reflex) removed the incentives of Advanced Information sistemokvants acceptor of action results. The article reveals some genetic and biological properties of individually purchased motivations and accompanying information equivalents sistemokvants acceptor of action results, as well as forming the basis of this dynamic holographic images. It is suggested that the holographic images acceptor action results represent specific integration of molecular and atomic vibrations occurring in the form of neurons, glial cells and cerebral fluid. It is shown that the logic of building information sistemokvantovs acceptors results of action allows a system approach to explain the processes of consciousness and thinking.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):28-36
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THE SYSTEM ORGANISATION OF SUBJECTIVE PROCESSES IN A BRAIN
Yumatov E.A.
Abstract
Subjective state of the person can be registered distantly objectively. Existence of "a psychogenic physical field» of a brain which cannot be at the lifeless nature is stated. Interaction of neurophysiological and subjective processes in the system organization of purposeful behaviour is described. The paradigm, considering possibility of existence unique for a live brain of the physical phenomena, and their role in an origin of a subjective state are offered.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):37-45
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THE PSYCHOPHYSIOLOGICAL CHARACTERISTICS OF THE SELF-SELECTION MAN CONDITIONS FOR THE IMPLEMENTATION OF THE PERFORMANCE AND TACTICS TO ACHIEVE THE RESULT
Murtazina E.P.
Abstract
Research is devoted to the individually-typological features of the subject’s independent choice of the parameters surroundings and start signals during the Senso-motor testing. Identified the types of dynamics and gender differences in the successive subject’s selection of the speed of the senso-motor test. Shows their relationship to the success of the activities, with the changes in the variability of heart rate and the spectral and coherent EEG characteristics of different areas of the cerebral cortex.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):46-54
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IMPACT OF CHRONIC HEART FAILURE IN THE MANIFESTATION OF SEIZURE READINESS AND ITS ASSOCIATION WITH RESISTANCE TO HYPOXIA
Mamalyga M.L.
Abstract
Chronic heart failure (CHF) modulates the activity of monoaminergic (MA-) systems and increases seizure readiness, and the severity of seizure depends on the individual resistance of the organism to oxygen deficiency. Increasing seizure readiness, and reduction of monoamines in postictal period at high and low resistance of the animals with CHF gives reason to believe that the activity of MA-ergic system may be a factor limiting the implementation of compensatory capacities in heart failure. Postictal period against the background of heart failure is characterized by the marked reduction in aminergic tone in the brain regions studied low resistance of the animals that are likely to acquire pathogenetic importance and can be the basis for the occurrence of repeated seizures.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):55-59
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NATURAL SCIENCE CATEGORY OF SYMMETRY-ASYMMETRY IN BIOLOGY OF ADAPTATION: INVESTIGATION OF HUMAN ADAPTATION TO THE MAGNETIC WAVE FACTORE
Ukhov U.I., Krapivnikova O.V., Kositsin N.S.
Abstract
Using of symmetry-asymmetry category as identification in effects of the different factors to adaptation abilities of a whole organism at the model of stress-reaction to magnetic stimulation is discussed in the article. Sympathetic effects of regulation are researched by cardiointervalomethric method, using stress-index as the criteria of stress-level. It is shown that both low and high level of asymmetry in neural centers activities decreases effects of magnetic stimulation, dynamic in stress-index is dependent on asymmetry level too.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):60-64
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EFFECT OF THE DEGREE OF IMMUNOSUPPRESSION AND HIGHLY ACTIVE ANTIRETROVIRAL THERAPY ON SERUM IL-17 AND IL-10 LEVEL IN PATIENTS WITH HIV-INFECTION
Zhyvytsia D.G.
Abstract
We analyzed IL-17 and IL-10 serum levels in HIV-infected patients with different stage of disease, degree of immunodeficiency and treatment. We observed 70 patients with HIV infection. Among the patients studied 44 patients on antiretroviral therapy. HIV infection is marked increase in the concentration of IL-10, especially in patients with severe immunosuppression (CD4 <200 ml-1). In HIV-infected patients with severe immunosuppression, which do not receive highly active antiretroviral therapy, there is an increase of IL-10 and IL-17 in serum, which may indicate a systemic immune activation.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):65-69
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DRUG-DRUG INTERACTIONS IIKE A REASON OF ADVERSE DRUG REACTIONS
Kazakov A.S., Lepakhin V.K., Astakhova A.V.
Abstract
Drug-drug interactions are a serious public health problem because they are cause of adverse drug reactions and one of the reasons for hospitalization of patients. Many patient’s admissions associated with drug-drug interactions could be avoided by proper medical supervision over the condition of patients or by using of alternative drugs. The analysis of spontaneous reports was used for assessment of adverse drug reactions caused by drug-drug interactions and defined the scope of the problem in Russia.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):70-76
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COMPARATIVE HYGIENIC ANALYSIS OF AIR QUALITY IN RYAZAN DISTRICTS
Lyapkalo A.A., Dementiev A.A., Tsurgan A.M.
Abstract
In the article there are results of the comparative analysis of air quality in Ryazan districts according to the data of the analytical control over the content of nitrogen oxide and nitrogen dioxide, sulphur dioxide, carbon oxide, sum of hydrocarbons, plumbum and its inorganic compounds, formaldehyde and suspended substances. Ranking of the city districts was done in the dependence on air quality. It was revealed that the districts “Gorodskaya Roszha” and “City Centre” occupy the first and the second places correspondently by the size of specific emission, equivalent emissions regarding reflex and resorptive effect and indices of emission hazard rating of interdistrict motor transport.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):77-82
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ANALYSIS OF PERINATAL CENTER IN A MULTILEVEL SYSTEM OF HEALTH CARE FOR WOMEN DURING PREGNANCY, CHILDBIRTH AND THE POSTPARTUM PERIOD (for example, the Ryazan region)
Petrova E.I., Medvedeva O.V.
Abstract
The paper presents an analysis of the Ryazan regional perinatal center in the development and improvement of obstetric care, introduction to practical health of modern medical technology. Given the specifics of the particular attention paid to the problem of providing highly specialized medical care for women of reproductive age.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):83-86
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THE HEALTH STATUS OF SOCIALLY VULNERABLE POPULATION GROUPS
Chirkov V.A., Breusov A.V.
Abstract
In the course of the research were identified and reviewed a causal link between the main factors (age, sex, education level, etc.) and the health status of socially vulnerable groups of the population of the city of Moscow. It is established, that consider themselves healthy and practically healthy 68% of the patients themselves as 10%, are not interested in their health 22% of respondents. The share of persons who consider themselves sick, increases with age in an exponential curve. The tendency of the revaluation of the level of health among people with chronic diseases, which testifies to the shortcomings in the prevention work of primary health care services.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):87-91
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PRIORITY question OF occupational hygiene AT THE ENTERPRISES OF THE SECONDARY LEAD
Chudinin N.V., Kiryushin V.A.
Abstract
Conditions of work in the secondary lead metallurgy is largely related to the technology of raw materials processing. Complexes sanitary-and-hygienic assessment of the lead recycling technologies allows seriously and purposefully develop preventive activities aimed at the improvement of working conditions and health of workers.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):92-97
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THE MEDICAL ACTIVITY OF PATIENTS WITH BRONCHIAL ASTHMA
Uryasev O.M., Konovalov O.E., Kicha D.I.
Abstract
The paper presents the characteristics of medical activity of 414 patients in the Ryazan Regional Hospital. The issues of the regularity of observing and passing medical examinations, compliance with the doctor's recommendations, self-medication are considered taking into account gender features.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):98-100
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HEART RATE VARIABILITY IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ST-SEGMENT ELEVATION ON THE BACKGROUND THROMBOLYTIC THERAPY
Girivenko A.I., Nizov A.A.
Abstract
The heart rate variability in patients with acute coronary syndrome with ST-segment elevation in the ECG and their changes against thrombolytic therapy depending on its performance. Shows the evolution of heart rate variability depending on the efficacy of thrombolytic therapy.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):101-106
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THE INFRADIAN RHYTHMS OF CORTISOL AND THYROID HORMONES AT WOMAN OF REPRODUCTIVE AGE
Diatroptov M.E., Simonova E.Y., Diatroptova M.A.
Abstract
The levels of cortisol, free and total thyroxin in the serum of the 6 th woman of 23-33 aged old in the follicular phase of menstrual cycle was studied by ELISA method. The cortisol level was fluctuated during the 4-day period. The levels of free and total thyroxin were changed in the 3-day period. Both fluctuations were synchronous in all studied woman. Revealed biological rhythms of glucocorticoids and thyroid hormones should be taken into account when hormonal and immunologic status of healthy woman is researched and corrective methods of pathologic states are developed.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):107-113
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ASPECTS OF Ethico-deontological AND LEGAL ASPECTS OF RENDERING the dermatovenerological help to the population
Zhiltsova E.E.
Abstract
The paper presents the results of a poll of 578 patients who are residents of the Ryazan region who applied for dermatovenerological help. The issues of patient satisfaction by medical help obtained and the conditions of its reception as well as the attitude of medical workers are considered. The ethical, deontological and legal problems of rendering dermatovenerological help to the population are analyzed.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):114-117
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INTERACTION OF COMPOSITE MESH Implanted With peritoneum abdominoplasty
Vorovskii O.O.
Abstract
An experimental study on 10 outbred dogs, of which 6 (main group) into the peritoneal cavity of a polypropylene mesh was implanted helium-coated cellulose. In all cases, the implants are contacted with the loops of the small intestine. Three months later by histological examination of a strong link ("rooting") polypropylene mesh implanted with adipose tissue of the greater omentum dog in the absence of alterative changes in the implant, and a helium coating of cellulose prevented the formation of adhesions with the surrounding organs of the abdominal cavity.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):118-123
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PUNCTURE DRAINING TREATMENT OF PANCREATIC CYSTS IN CASE OF CHRONIC PANCREATITIS
Tarasenko S.V., Karyukhin I.V., Rakhmaev T.S., Lunkov I.A., Nikitin D.A., Donyukova S.P., Panina N.Y.
Abstract
The paper analyzes the results of percutaneous puncture draining treatment for pancreatic cysts in 38 patients in case of chronic pancreatitis in 2008 to 2012. The first stage of treatment was carried out percutaneous thin needle aspiration puncture of the contents of the cavity cysts under ultrasound guidance. A different approach to diagnostics as well as to surgical management of complications is offered. The early and accurate diagnosis of pancreatic cysts, in which ultrasound study plays a major role, is a condition for their successful treatment. Indications to different surgical methods are formulated differently depending on complications of cysts, localization, sizes, «maturity» of cyst walls, communication with main pancreatic duct. Puncture treatment was used in 7 patients; percutaneous drainage under ultrasound guidance was performed in 31 patients. No mortality rate was noted. Miniinvasive puncture-draining interventions were effective in 33 patients, which amounted to 86,9 %.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):124-129
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IMPORTANCE OF MARKERS OF THE PROLIFERATION AND APOPTOSIS FOR OVARIAN BODERLINE TUMOURS
Vinogradov I.I., Zavalishina L.E., Andreeva Y.Y., Akhidova E.V., Volpina O.M., Volkova T.D., Koroev D.O.
Abstract
For today, one of actual problems in gynecologic pathology are borderline tumours of the ovary to which frame of a case rate the high specific gravity is compounded by women of reproductive age. Thereupon often there is a question about safety treatment methods, that dictates necessity of an assessment of risk of development of recurrence of disease. In present article attempt to define prognostic importance of markers of proliferative activity (ki67, cyclin D1, p21), and pro-and antiapoptotic markers (p53, bax, bcl-2, survivin) for definition potentially an aggressive behavior of ovarian borderline tumour.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):130-136
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DISEASES OF THYROID GLAND AS RISK FACTOR IN PRIMARY OPEN ANGLE GLAUCOMA DEVELOPMENT
Lichvantseva V.G., Korosteleva Y.V., Tabeyeva K.I., Vygodin V.A.
Abstract
Glaucoma is a multifactor disease. The data concerning the correlation between the pathology of thyroid gland and glaucoma appeared at the end of the last century. The revealing of the disease spread plays an important role in confirming the connection of glaucoma development on the background of thyroid gland disease.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):137-142
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COMPARATIVE ANALYSIS OF ELEMENT, CARBOHYDRATE AND AMINO ACID COMPOSITION OF VALERIANA OFFICINALIS UNDERGROUND ORGANS
Fursa N.S., Karavanova E.N.
Abstract
The results of determination of analysis of 6 macro- and 54 microelements, 3 free and 4 bound sugars, 8 irreplaceable and 11 replaceable amino acids content in Valeriana officinalis rhizomes, roots and rhizomes with roots were analyzed.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):143-147
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THE ROLE OF OXIDATIVE STRESS IN THE PATHOGENESIS OF THE BACTERIAL CORNEAL ULCER
Shchulkin A.V., Kolesnikov A.V., Barenina O.I., Nikolaev M.N., Nikiforov A.A.
Abstract
In the article the current ideas of a role of free radical processes in physiology of a cornea and microorganisms are surveyed. The role of an oxidative stress in the pathogenesis of the bacterial corneal ulcer is discussed. The review of researches on the application of antioxidants for treatment of a bacterial ulcer is done.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):148-152
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MODERN ASPECTS OF ETIOLOGY AND PATHOGENESIS OF DISEASES OF PARODONT
Fuks E.I., Kareva U.A., Galizina O.A., Tabolina E.S.
Abstract
The article is devoted to the review of the modern literary data regarding etiology and pathogenesis of diseases of parodont. Many general and local factors take part in development and progression of inflammatory diseases of parodont. Role of chronic odontogenic infection in development of somatic pathology is described in this article.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):153-160
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Cell and cell-MATRIX INTERACTIONS IN TUMORS: CURRENT STATE OF THE PROBLEM
Mnikhovich M.V.
Abstract
In an article in the form of a literature review highlights current understanding of cell-cell and cell-matrix interactions in tumors.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):161-171
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LIFE SCRIPTS IN VIEW OF THE FUNCTIONAL SYSTEMS THEORY BY P.K. ANOHIN (In search of common points of psychology, psychiatry, and psychophysiology)
Chustov D.I., Fedotov M.A., Novikov S.A.
Abstract
The article represents the review of contemporary understanding of life scripts in view of the functional systems theory by P.K. Anohin. The concepts of the action result acceptor and script decision as the central backbone factor are compared. From the point of view of relativistic theories of psyche the process of metalization of narrative life script is described. As exemplified by autobiographic stories and contemporary scientific investigations, psychological aspects of “anticipatory reflection” are shown.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):172-176
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DEVELOPMENT OF RULES OF THE RUSSIAN PENAL LEGISLATION ON RESPONSIBILITY OF DRUNK CRIMES
Peremolotova L.Y., Shilov A.I.
Abstract
The article deals with the genesis of penal legislation in Russia concerning crimes committed in a state of alcoholic intoxication in XX-XXI centuries. Based on the criminological, social and legal analyses of anti-alcohol policy the authors suggest that in the beginning of XXI century alcoholic situation in Russia is characterized by increase in the issue urgency and further expansion of alcohol-related crimes.
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):177-182
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ACADEMICIAN OF RAMS K.V. SUDAKOV
- -.
Abstract
I.P. Pavlov Russian Medical Biological Herald. 2013;21(3):183-183
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