Quality of life after Whipple pancreatoduodenectomy and pylorus-preserving pancreatoduodenectomy: a comparative study

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Abstract


The authors performed a comparative analysis of the Quality of life (QOL) in 97 patients after pancreatoduodenectomy, 55 of whom underwent pylorus-preserving surgery (PPDE), and 42 underwent classic Whipple procedure (GPDE). QOL was evaluated using questionnaire EORTC-QLQ-C30, version 3.0, and both analyzed groups were divided into 3 subgroups according to the time period after the surgery (less than 6 mo, 6-12 mo, and more than 12 mo). All the patients were operated on for pancreatic or periampullary cancer. During the first period after surgery (less than 6 mo), the integral QOL index is lower than in patients who were examined after the first 6 mo. After PPDE, parameters of physical, role, emotional, cognitive, and social functioning were higher than after GPDE; however, these differences were not statistically significant (p > 0,05). Indicators of QOL have changed with time, but intergroup (PPDE vs GPDE) differences were not statistically significant in every analyzed time period after surgery. Financial constrains were registered in patients of both groups and at different times after surgical treatment.


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About the authors

Nikolay Yurevich Kokhanenko

St. Petersburg State Pediatric Medical University

Author for correspondence.
Email: kohanenko@list.ru

MD, PhD, Dr Med Sci, Professor, Head of the Prof. A. A. Rusanov Department of Faculty Surgery

Konstantin Vadimovich Pavelets

St. Petersburg State City Mariinskaja Hospital

Email: 9972497@list.ru

MD, PhD, Dr Med Sci, Associate Professor, Chief of Surgery

Yuri Vasilevich Radionov

St. Petersburg State Pokrovskaja Hospital

Email: Radionov8604@gmail.com

surgeon

Yurii Nikolaevich Shiryajev

St. Petersburg State Pediatric Medical University

Email: shiryajev@yandex.ru

Associate Professor, Prof. A. A. Rusanov Department of Faculty Surgery

Natalya Yurevna Borisova

St. Petersburg State Pediatric Medical University

Email: natzur@mail.ru

Assistant, Prof. A. A. Rusanov Department of Faculty Surgery

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Copyright (c) 2015 Kokhanenko N.Y., Pavelets K.V., Radionov Y.V., Shiryajev Y.N., Borisova N.Y.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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