儿童阻塞性睡眠呼吸暂停综合征:血管系统结构和功能变化的超声诊断的先决条件和可能性
- 作者: Bolshakova S.E.1, Madaeva I.M.1, Berdina O.N.1, Bugun O.V.1, Rychkova L.V.1
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隶属关系:
- Scientific Center of Family Health Problems and Human Reproduction
- 期: 卷 12, 编号 2 (2021)
- 页面: 65-72
- 栏目: Reviews
- URL: https://journals.eco-vector.com/pediatr/article/view/76721
- DOI: https://doi.org/10.17816/PED12265-72
- ID: 76721
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详细
在一般人群中,儿童睡眠期间呼吸系统疾病的患病率为1–5%。关于儿童阻塞性睡眠呼吸暂停综合征(OSAS)及其与心血管病理学的联系的研究很少,而且常常相互矛盾。本综述探讨了阻塞性睡眠呼吸暂停综合征患者心血管系统病理变化的发展机制,描述了内皮功能障碍在儿童阻塞性睡眠呼吸暂停综合征中作为血管损伤的主要标志的作用。还提供了超声方法来研究睡眠期间患有阻塞性呼吸障碍的儿童患者的血管系统。本文分析了在阻塞性睡眠呼吸暂停综合征条件下,利用经颅双工扫描大脑基底部血管的脑血流动力学研究及血管重构引起的脑血流动力学变化。讨论了在反应性充血试验中超声评价内皮依赖性肱动脉扩张作为诊断阻塞性睡眠呼吸暂停综合征儿童内皮功能障碍的功能方法的可能性。这些方法的使用将使及时识别血管的结构和功能变化成为可能,这将允许确定早期预防的载体,并从病理上证实从睡眠医学的角度治疗阻塞性睡眠呼吸暂停综合征儿童的各种心血管疾病的创新方法。
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作者简介
Svetlana Bolshakova
Scientific Center of Family Health Problems and Human Reproduction
编辑信件的主要联系方式.
Email: sebol@bk.ru
MD, PhD, Cand. Sci. (Med.), Researcher, Laboratory of Somnology and Neurophysiology
俄罗斯联邦, IrkutskIrina Madaeva
Scientific Center of Family Health Problems and Human Reproduction
Email: iphr@sbamsr.irk.ru
MD, PhD, Dr, Sci. (Med.), Project Leader, Laboratory of Somnology and Neurophysiology
俄罗斯联邦, IrkutskOlga Berdina
Scientific Center of Family Health Problems and Human Reproduction
Email: iphr@sbamsr.irk.ru
MD, PhD, Cand. Sci. (Med.), Leading Scientist, Laboratory of Somnology and Neurophysiology
俄罗斯联邦, IrkutskOlga Bugun
Scientific Center of Family Health Problems and Human Reproduction
Email: iphr@sbamsr.irk.ru
MD, PhD, Dr. Sci. (Med.), Deputy Director
俄罗斯联邦, IrkutskLyubov Rychkova
Scientific Center of Family Health Problems and Human Reproduction
Email: iphr@sbamsr.irk.ru
MD, PhD, Dr. Sci. (Med.), Professor, director
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