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卷 28, 编号 6 (2017)
- 年: 2017
- 文章: 29
- URL: https://journals.eco-vector.com/0236-3054/issue/view/5972
Articles
Vstupitel'noe slovo
Vrach. 2017;28(6):2-2
2-2
FEATURES OF PREVENTIVE MEASURES IN ELDERLY PEOPLE IN RUSSIA
摘要
The paper analyzes the possibilities of effective primary, secondary (screenings) and tertiary prevention in a population aged over 65 years and at the individual level. It describes the Crystal risk assessment model created according to the results of epidemiological studies in Russia.
Vrach. 2017;28(6):3-7
3-7
PAIN MANAGEMENT IN PATIENTS WITH DEMENTIA
摘要
The paper considers the issues of pain treatment in patients with severe forms of dementia. The problem is extremely urgent both for long-term healthcare facilities, psychogeriatric hospitals, and the outpatient facility personnel caring for these patients together with their relatives. International guidelines are quoted in detail; the organizational aspects of care for dementia patients with severe pain syndrome are discussed. Tools for pain syndrome assessment are given.
Vrach. 2017;28(6):8-11
8-11
MYASTHENIA: CURRENT TREATMENT STRATEGIES
摘要
Myasthenia is a severe disease that results from an antibody-mediated autoimmune disorder of neuromuscular synaptic transmission. The high prevalence of the disease, the severity of its clinical manifestations, and the instability of the patients’ status even during therapy determine the urgency to elaborate optimal therapeutic strategies for the management of these patients. The paper presents current approaches to treating myasthenia, describes in detail drug treatment options and the possibility of surgical intervention, and gives data on the use of ozone therapy for this disease.
Vrach. 2017;28(6):12-15
12-15
VASCULAR COGNITIVE IMPAIRMENT: FROM PATHOGENESIS TO TREATMENT
摘要
The term vascular cognitive impairments (VCI) defines dementia and cognitive impairment no dementia, which are pathogenetically associated with cerebral vessel damage. The paper considers the etiology, pathogenesis, criteria for instrumental and clinical diagnosis, as well as VCI. The relationship between VCI and neurodegenerative diseases is discussed separately.
Vrach. 2017;28(6):16-19
16-19
THE EXAMINATION AND MANAGEMENT OF PATIENTS WITH COGNITIVE IMPAIRMENT
摘要
Cognitive impairment (CI) is one of the most common disorders among elderly and senile people. The prevalence of all CIs no dementia in people aged over 80 years is as high as 40 to 80% according to some data. The paper gives an algorithm for the diagnosis of CI and for the management of these patients.
Vrach. 2017;28(6):19-24
19-24
THE ROLE OF COGNITIVE DISORDERS AND OTHER GERIATRIC SYNDROMES IN THE FORMATION OF GERIATRIC STATUS IN PATIENTS WITH NEUROLOGICAL DISEASES
摘要
In this article the results of studies on prevalence of cognitive disorders in patients with neurological diseases such as abnormalities of the lumbosacral discogenic sciatica, cerebrovascular accident due to traumatic brain injury or cerebral infarction. We evaluated the role of the development of cognitive disorders in the formation of the geriatric status and the worsening of the flow of neurological diseases such patients.
Vrach. 2017;28(6):25-27
25-27
THE RISK OF COGNITIVE DEFICITS IN PATIENTS OF ELDERLY AGE WITH CORONARY HEART DISEASE, WHICH PLANS CORONARY ARTERY BYPASS GRAFTING
摘要
The article presents the review data to identify risks of development of cognitive deficit in patients of senior age groups with coronary heart disease, which shows coronary artery bypass grafting. We presents the latest research on biomarkers of cognitive impairment, and the innovation of ways of correction of the cognitive deficit in these patients.
Vrach. 2017;28(6):28-29
28-29
MODERN BIOMARKERS OF AGING AND COGNITIVE DISORDERS
摘要
The article presents the review of modern new biomarkers of aging. We have given the promising capabilities of biomolecular medicine in the early diagnosis of cognitive disorders. We presents the data on this new marker as an unconjugated bilirubin, end products of glycation, metalloprotein, DNA methylation, microRNA.
Vrach. 2017;28(6):30-32
30-32
A MATHEMATICAL MODELING METHOD IN ASSESSING THE RATE OF AGING
摘要
The paper presents a correlation analysis of biological markers for aging in combat veterans. Data on psychosocial, clinical, laboratory, and functional parameters of the body are used. Knowing some parameters of homeostasis and the indicators of cardiovascular system functioning, the rate of aging can be determined using the given formulas.
Vrach. 2017;28(6):33-35
33-35
THE TIME COURSE OF CHANGES IN THE CONCENTRATION OF BRAIN-DERIVED NEUROTROPHIC FACTOR DURING THIAPRIDE THERAPY FOR MENTAL CONFUSION
摘要
The paper considers the clinical results of using thiapride and quetiapine in patients with mental confusion and the time course of changes in the concentration of brain-derived neurotrophic factor (BDNF) during the above treatment. The changes in the BDNF concentration were characterized by its reduction with the similar clinical results of therapy. There are possible explanations for this and a conclusion about the similarity of the effectiveness and safety of using thiapride and the atypical antipsychotic in the aspect of their potential effects on the processes controlled by BDNF.
Vrach. 2017;28(6):35-38
35-38
FIXED-DOSE TRIPLE COMBINATION OF ANTIHYPERTENSIVE DRUGS FOR HYPERTENSION
摘要
The paper presents information on triple antihypertensive therapy for hypertension and gives the results indicating its higher efficiency, safety in the use of amlodipine, indapamide, and perindopril.
Vrach. 2017;28(6):38-40
38-40
COMBINATION THERAPY FOR MUSCULOSKELETAL DISEASES WITH TOPICAL IBUPROFEN FORMULATIONS
摘要
The topical application of ibuprofen (Dolgit®) as cream and gel provides an optimal drug concentration in the adjacent tissues in the immediate vicinity of a pathological focus, which is most important in musculoskeletal injuries (bruises, sprains of the capsular-ligament apparatus) and in patients with postoperative bone and joint diseases, which allows the drug to be recommended for the combination treatment of musculoskeletal diseases and injuries in individuals of different age groups.
Vrach. 2017;28(6):41-44
41-44
EVALUATION OF THE EFFICACY AND SAFETY OF FLUPIRTINE IN THE THERAPY OF ACUTE NONSPECIFIC LOW BACK PAIN
摘要
Flupirtine is a promising agent for the relief of pain of various origin. It has analgesic, muscle relaxant, and neuroprotective activities. The pharmacological properties of flupirtine allow it to be effectively used to treat low back pain, especially in patients with comorbidity. The analgesic activity and tolerability of flupirtine in the therapy of acute nonspecific low back pain in patients with comorbidity.
Vrach. 2017;28(6):45-47
45-47
INDIVIDUALIZATION OF TREATMENT AND REHABILITATION PROGRAMS IN GERIATRICS
摘要
The paper gives the results of evaluating cognitive impairment and anxiety-depressive syndrome in elderly patients with hypertension in order to explore the possibility of individualization of treatment and rehabilitation programs for geriatric syndromes.
Vrach. 2017;28(6):47-51
47-51
THE THERAPEUTIC ENVIRONMENT FOR PATIENTS WITH COGNITIVE IMPAIRMENT IN SOCIAL SERVICE HOSPITALS
摘要
The therapeutic environment for elderly patients with cognitive impairment should be understandable and safe and should mould a sense of demand, interest, and permanent employment, which is aimed at maintaining and compensating for mental disorders.
Vrach. 2017;28(6):51-53
51-53
ASSESSMENT OF VASCULAR WALL STIFFNESS IN PATIENTS WITH CO-MORBIDITY DURING COMBINED AND TRADITIONAL ANTIHYPERTENSIVE THERAPY
摘要
The parameters of 24-hour blood vessel stiffness monitoring were investigated in patients with type 2 diabetes mellitus concurrent with grade II and III hypertension during combined therapy with ramipril and amlodipine.
Vrach. 2017;28(6):53-54
53-54
CHANGE OF HEART RATE VARIABILITY IN PATIENTS WITH DIFFERENT CLINICAL FORMS OF CORONARY HEART DISEASE
摘要
Measurement of heart rate variability is an available technique for assessing the autonomic regulation of cardiac activity. In elderly patients with coronary heart disease, cardiac autonomic imbalance with sympathetic predominance due to reduced vagal tone is concurrent with both a history of myocardial infarction and with unstable angina.
Vrach. 2017;28(6):55-57
55-57
MARKERS OF COGNITIVE FRAILTY IN AGING AND ARTERIAL HYPERTENSION IN AMBULATORY PRACTICE
摘要
To assess the severity of early and dodement cognitive impairments, the cognitive function was assessed using the Montreal Scale (MoCA test), instrumental daily activity on the Lauton-Brody scale, quality of life measures using the SF-36 questionnaire in 134 patients with arterial hypertension and 117 healthy people of middle, elderly and senile age. It was found that the markers of cognitive frailty, manifested by a reduction in the volume of visual-constructive skills and memory, are most pronounced when combined involutive changes and arterial hypertension in patients of senile age.
Vrach. 2017;28(6):58-60
58-60
THE INTERACTION OF COGNITIVE DEFICIT AND SYNDROME MALNUTRITION IN PATIENTS WITH CARDIO-VASCULAR DISORDERS
摘要
The article highlights the results of studies on the interaction of cognitive deficit and syndrome malnutrition in patients of older age groups with arterial hypertension. We described the analysis of the geriatric status and proposed rehabilitation treatment measures for comprehensive management of such patients.
Vrach. 2017;28(6):60-62
60-62
SPECIFIC FEATURES OF CLINICAL COURSE AND TREATMENT OF ALCOHOLISM IN ELDERLY PATIENTS
摘要
The paper reflects the characteristics of the social status of elderly patients with chronic alcoholism. It describes the most pronounced symptoms of the disease, the background conditions, the specific features of treatment, and the principles of rehabilitation.
Vrach. 2017;28(6):63-65
63-65
TYPES OF COGNITIVE DISORDERS IN THE PRACTICE OF A SPECIALIST OF ANTI-AGEING MEDICINE
摘要
The article describes the main types of cognitive impairment encountered in the practice of a specialist of anti-ageing medicine, in particular, orthorexia nervosa, dismorphomania and body dysmorphic disorder. The questions of pathogenesis, early diagnosis. We offered modern ways of correction of cognitive disorders.
Vrach. 2017;28(6):65-68
65-68
THE INCIDENCE OF HYPERTENSION IN ELDERLY PATIENTS WITH CORONARY HEART DISEASE IN THE FAR NORTH
摘要
The incidence of hypertension has been studied in elderly patients with or without coronary heart disease who live in the Far North.
Vrach. 2017;28(6):68-71
68-71
THE PORTRAIT OF A LONG-LIVING PERSON IN YAKUTIA
摘要
The results of studying the health status and lifestyle of a female centenarian living in Yakutia reveal the secrets of her longevity.
Vrach. 2017;28(6):71-73
71-73
A CARE HOME FOR THE ELDERLY
摘要
The authors describe their own experience in organizing health and social care in the private geriatric facility, such as a care home for the elderly and disabled.
Vrach. 2017;28(6):73-75
73-75
A CASE OF HEREDITARY DISEASE IN ONE FAMILY HAVING SEVERAL CHILDREN WITH DIFFERENT BIOLOGICAL FATHERS
摘要
Mucopolysaccharidosis type 1 (MPS 1) is included by the Ministry of Health of the Russian Federation in the list of 700 orphan diseases. The etiopathogenesis of MPS 1 is caused by mutations in the structural gene for the lysosomal enzyme а-L-iduronidase (IDUA), which is the reason for the accumulation of products of incomplete glycosaminoglycan (GAG) disintegration in the cell lysosomes. The mutations are inherited in an autosomal recessive pattern. There are currently more than 100 known mutations in the IDUA gene. Different mutations cause different clinical forms of MPS 1, such as Hurler, Hurler-Sheie, and Sheie syndromes. The polymorphism of clinical manifestations and the low incidence of MPS 1 impede its timely diagnosis and, accordingly, early initiation of therapy. The diagnosis of MPS 1 is based on the identification of the specific phenotype of patients, the determination of the urinary excretion of GAGs and their fractions, tandem mass spectrometry, and DNA diagnosis. Enzyme replacement therapy and bone marrow transplantation improve the follow-up of patients with MPS 1.
Vrach. 2017;28(6):76-80
76-80
A FAMILY CASE OF FABRY DISEASE
摘要
The paper describes a family case of rare lysosomal storage disease. The diagnosis of Fabry disease (FD) is based on its clinical symptoms, enzyme diagnosis, and molecular genetic diagnosis. The paper also analyzes the phenotypic spectrum and discusses early diagnosis and enzyme replacement therapy in children with FD in the Republic of Sakha (Yakutia). The diagnosis of the orphan disease represents a challenge due to its nonspecific symptoms. Screening high-risk individuals is recommended for the early detection of FD.
Vrach. 2017;28(6):81-85
81-85
Konkurs nauchno-prakticheskikh rabot kompanii Parafarm
Vrach. 2017;28(6):87-87
87-87
Aseptisorb®
Vrach. 2017;28(6):88-88
88-88