Physicochemical activity of solutions as an integral part of the mechanism of local drug action
- Authors: Urakov A.L.1, Urakova N.A.2, Alyes M.Y.1, Nikityuk D.B.3, Gurevich K.G.4, Lovtsova L.V.5, Kasatkin A.A.2, Reshetnikov A.P.2
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Affiliations:
- Udmurt Federal Research Center, Ural Branch, Russian Academy of Sciences
- Izhevsk State Medical Academy
- Federal Research Center for Nutrition, Biotechnology, and Food Safety
- I. Evdokinov Moscow State University of Medicine and Dentistry
- Volga Research Medical University
- Issue: Vol 68, No 6 (2019)
- Pages: 42-49
- Section: Articles
- URL: https://journals.eco-vector.com/0367-3014/article/view/113163
- ID: 113163
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About the authors
Aleksandr L. Urakov
Udmurt Federal Research Center, Ural Branch, Russian Academy of Sciences
Email: urakoval@live.ru
Leading Researcher of the Department of Modeling and Synthesis of Technological Processes, Doctor of Medical Sciences, Professor Izhevsk 426067, Russian Federation
Natalia A. Urakova
Izhevsk State Medical Academy
Email: urakovanatal@mail.ru
Acting Associate Professor of the Department of Obstetrics and Gynecology, Faculty of Retraining and Advanced Training, Candidate of Medical Sciences, Associate Professor Izhevsk 426034, Russian Federation
Mihael Yu. Alyes
Udmurt Federal Research Center, Ural Branch, Russian Academy of Sciences
Email: udnc@udman.ru
Director , doctor of physical and mathematical Sciences, Professor. Izhevsk 426067, Russian Federation
Dmitry B. Nikityuk
Federal Research Center for Nutrition, Biotechnology, and Food Safety
Email: nikitjuk@ion.ru
Director , doctor of medical Sciences, Professor, corresponding member of the RAS Moscow 109240, Russian Federation
Konstantin G. Gurevich
I. Evdokinov Moscow State University of Medicine and Dentistry
Email: kgurevich@mail.ru
Head of the Department of UNESCO «Healthy Lifestyle - the Key to Successful Development», Doctor of Medical Sciences, Professor. Moscow 127473, Russian Federation
Lyubov V. Lovtsova
Volga Research Medical University
Email: lovcovalubov@mail.ru
head of the Department of General and clinical pharmacology, doctor of medical Sciences, associate Professor. Nizhny Novgorod 603950, Russian Federation
Anton A. Kasatkin
Izhevsk State Medical Academy
Email: antkasatkin@mail.ru
acting assistant of the Department of General and clinical pharmacology, candidate of medical Sciences. Izhevsk 426034, Russian Federation
Alexey P. Reshetnikov
Izhevsk State Medical Academy
Email: areshetnikov@list.ru
acting assistant of the Department of General and clinical pharmacology , candidate of medical Sciences. Izhevsk 426034, Russian Federation
References
- Urakov A., Urakova N., Kasatkin A. et al. Physical-Chemical Aggressiveness of Solutions of Medicines as a Factor in the Rheology of the Blood Inside Veins and Catheters. Journal of Chemistry and Chemical Engineering, 2014; 8 (1): 61-5
- Ураков А.Л., Стрелков Н.С., Уракова Н.А.и др.Физико-химические и биофизические факторы постинъекционной агрессивности растворов лекарственных средств в инфильтрированных тканях и способы предотвращения некрозов. Патологическая физиология и экспериментальная терапия, 2010; 1: 20-4
- Kasatkin A., Urakov A., Lukoyanov I. Nonsteroidal anti-inflammatory drugs causing local inflammation of tissue at the site of injection. J. Pharmacol. Pharmacother., 2016; 7: 26-8.
- Ураков А.Л., Уракова Н.А., Касаткин А.А. Повышение безопасности внутривенных инъекций. Военно-медицинский журнал, 2013; 9: 73-5
- Urakov A.L., Dementyev V.B., Urakova N.A. et al. Clinical significance of physical-chemical processes determining qualitative and quantitative characteristics of post-injection diffusion of drug solutions in patient's soft tissues. Химическая физика и мезоскопия, 2007; 9 (2): 105-11.
- Urakov A., Urakova N., Kasatkin A. et al. Infrared thermography skin at the injection site as a way of timely detection injection disease. Thermology International, 2015; 25 (1): 30.
- Urakov A., Urakova N. Temperature of the site of injection in subjects with suspected “injection's disease". Thermology International, 2014; 24 (2): 63-4.
- Urakov A., Urakova N. Rheology and physical-chemical characteristics of the solutions of the medicines. J. Phys.: Conf. Ser., 2015; 602: 012043.
- Urakov A., Urakova N., Kasatkin A. Safe injections of anti-microbial drugs. J. Infect. Prevent., 2013; 14 (1): 9.
- Urakov A.L., Urakova N.A. Thermography of the skin as a method of increasing local injection safety. Thermology International, 2013; 23 (2): 70-2.
- Urakov A.L.The change of physical-chemical factors of the local interaction with the human body as the basis for the creation of materials with new properties. Epytoanyag - Journal of Silicate Based and Composite Materials. 2015; 67 (1): 2-6.