THE ROLE OF REAL CLINICAL PRACTICE DATA IN MODERN HEALTHCARE
- Authors: Novoderezhkina E.A.1, Zyryanov S.K.1
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Affiliations:
- Peoples' Friendship University of Russia
- Issue: Vol 70, No 3 (2021)
- Pages: 5-10
- Section: Articles
- URL: https://journals.eco-vector.com/0367-3014/article/view/113489
- DOI: https://doi.org/10.29296/25419218-2021-03-01
- ID: 113489
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Abstract
The paper defines the place of real world evidence (RWE) in evidence-based medicine and its role in modern healthcare by the example of psoriasis on the basis of the works published in the MedLine, PubMed, and Cochrane Library databases in 2010-2020. It considers the advantages and disadvantages of RWE studies and randomized clinical trials (RCTs). It is noted that the data of both types of studies can complement each other. In the foreseeable future, RCTs will remain necessary for the initial approval of drugs and treatments that must be initially demonstrated to be effective in the primary target group and for the primary indication in the RCTs before they can be introduced into the RWE. RWE studies will be able to more effectively identify the unresolved medical needs and molecular targets for further elaboration of therapeutic approaches, to register drugs, and to expand their range of indications. As the drawbacks in the structure of RWE studies are corrected, the importance of this method will grow in the clinical, regulatory, and economic areas of healthcare.
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About the authors
Evgenia Alekseevna Novoderezhkina
Peoples' Friendship University of Russia
Email: evgeniyanovoderezhkina@gmail.com
external doctoral candidate, Department of General and Clinical Pharmacology 6, Miklukho-Maklai St., Moscow 117198, Russian Federation
Sergey Kensarinovich Zyryanov
Peoples' Friendship University of Russia
Email: zyryanov-sk@rudn.ru
Head of the Department of General and Clinical Pharmacology 6, Miklukho-Maklai St., Moscow 117198, Russian Federation
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