Selenium and selenium-containing drugs: antioxidant and anti-aging effects, possibility of application in cardiology

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Abstract

Objective of the study. A literature review in which scientists have studied the antioxidant, anti-aging effects of selenium, possibility of preventive maintenance of the microelement deficiency with the help of selenium containing preparations for lowering risk of cardiovascular disease (CVD).

Material and methods. A review of 36 publications by Russian and foreign researchers was carried out. The authors studied the antioxidant, anti-aging effect of selenium and the possibility to prevent selenium deficiency by additional use of selenium-containing drugs to reduce the risk of cardiovascular disease.

Results. Selenium is one of the irreplaceable trace elements. It is necessary for normal vital activity of humans. Selenium deficiency is associated with increased risk of cardiovascular diseases, immune system dysfunction, mental deficiency and death. The optimal daily intake of selenium for adult men and women is 70 and 55 µg, respectively. Foods of plant and animal origin are the main source of selenium for humans. If dietary intake of selenium is insufficient, the dietary intake ingestion of selenium with foodstuffs it is recommended to take biological supplements with this microelement.

Conclusions. Thus, selenium has antioxidant and anti-aging effects. Maintaining optimal selenium concentrations in the body through the addition of selenium-enriched food and/or dietary supplements and/or supplements with this trace element could be one of the ways to reduce the risk of developing and prevent CVD. In patients with low serum levels of selenium, supplementation with SELENBIO for Russian company "Parafarm" is recommended to use SELENBIO for patients with low serum selenium levels.

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About the authors

Dmitry Vasilievich Dedov

Tver State Medical University of the Ministry of Health of the Russian Federation; Regional Clinical Cardiological Dispensary

Author for correspondence.
Email: dedov_d@inbox.ru
ORCID iD: 0000-0002-3922-3207

MD, PhD, associate professor, professor of the department of Tver State Medical University; cardiologist of Tver Regional Clinical Cardiology Dispensary

Russian Federation, Sovetskaya str., 4, Tver, 170100; Komsomolsky Avenue, 19, Tver, 170041, Russian Federation

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