Enterosorbents of Russia, the European Union and Arab countries
- Authors: Bondarev A.V.1, Zhilyakova E.T.1, Riffi M.1
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Affiliations:
- Belgorod State National Research University
- Issue: Vol 72, No 5 (2023)
- Pages: 26-38
- Section: Technology of medicines
- URL: https://journals.eco-vector.com/0367-3014/article/view/568096
- DOI: https://doi.org/10.29296/25419218-2023-05-04
- ID: 568096
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Abstract
Introduction. Enterosorbents are a group of drugs with sorption-detoxic effect widely used in the world. Currently, in Russia, as in different countries, there is a wide range of drugs assigned to the group of enterosorbents, however, a detailed consideration of this issue shows that there is a limited number of analytical publications devoted to a comparative review of this kind of medicaments.
Objective: to overview the registered enterosorbents, pharmaceutical substances for their production in Russia, the European Union and Arab countries, to consider the classification of enterosorbents according to the active substance.
Material and methods. Content analysis of official sources of information about medicines, statistical analysis (Excel, 2019), graphical analysis. We reviewed the State Register of Medicines of Russia, the Register of Medicines of the European Union and the registers of medicines of Arab countries (Algeria, Libya and Saudi Arabia).
Results. According to the international analysis of enterosorbents, those belong to the A07BA group – charcoal preparations, that are registered in all the countries under consideration, and the A07BC group – the Other intestinal adsorbents, which are, in the countries under consideration represented by 7 active substances: hydrolysis lignin, dioctahedral smectite, colloidal silicon dioxide, povidone, polymethylsiloxane polyhydrate, kaolin and pectin.
Conclusion. There are 6 groups of active substances of enterosorbents registered in Russia, the most used is the activated carbon group. There are 6 groups registered in the European Union, two of which are Pectin and Kaolin. Only 3 groups of active substances are registered in Arab countries. The most known of enterosorbents, both in the European Union and in Arab countries, is the Dioctahedral Smectite group.
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About the authors
Alexander V. Bondarev
Belgorod State National Research University
Author for correspondence.
Email: bondarev_a@bsu.edu.ru
ORCID iD: 0000-0003-0077-7031
PhD in pharmaceutical sciences, associate professor of the Department of Pharmaceutical Technology
Russian Federation, Victory str., 85, Belgorod, 308015Elena T. Zhilyakova
Belgorod State National Research University
Email: ezhilyakova@bsu.edu.ru
ORCID iD: 0000-0002-8685-1601
PhD in pharmaceutical sciences, professor, head of the Department of Pharmaceutical Technology of Institute of Pharmacy, Chemistry and Biology
Russian Federation, Victory str., 85, Belgorod, 308015Mohammed Riffi
Belgorod State National Research University
Email: riffimohammed68@gmail.com
ORCID iD: 0000-0002-2657-7305
PhD student of the Department of Pharmaceutical Technology
Russian Federation, Victory str., 85, Belgorod, 308015References
- Bondarev A.V., Zhilyakova E.T. Analysis of the Russian pharmaceutical market of enterosorption drugs. Russian and foreign markets, 2014; 3 : 40–7 (in Russian)
- Oursova N.I. The place of enterosorbents in the treatment of endogenous intoxication syndrome. Vopr. sovremen. рediatrii. 2012; 11 (6): 26–31 (in Russian)
- Nikolaev V.G., Samsonov V.A. Analysis of medical use of carbon adsorbents in China and additional possibilities in this field achieved in Ukraine. Artif. Cells Nanomed. Biotechnol. 2014; 42 (1): 1–5. doi: 10.3109/21691401.2013.856017 (in Russian)
- Panfilova V.N., Taranushenko T.E. The use of enterosorbents in clinical practice. PF. 2012; 6. URL: https://cyberleninka.ru/article/n/primenenie-enterosorbentov-v-klinicheskoy-praktike (date of access: 10/25/2022) (in Russian)
- Bondarev A.V. Analysis of the Russian pharmaceutical market of enterosorption drugs. Actual problems of the humanities and natural sciences. 2013; 10 (2): 259–61 (in Russian)
- Fatullayeva S.A review on enterosorbents and their application in clinical practice: Removal of toxic metals. Colloid and Interface Science Communications. 2021; 45: 1–11 (in Russian)
- Mikhalovsky S. Enterosorption in the treatment of heavy metal poisoning. Chemistery journal of Moldova. General, Industrial and Ecological Chemistry. 2021; 16 (2): 9–27 (in Russian)
- State register of medicines [Electronic resource]. Ministry of Health of the Russian Federation. M., 2022. Access mode: http://grls.rosminzdrav.ru.
- European Medicines Agency (EMA): National registers of authorized medicines. [Electronic resource]. URL: https://www.ema.europa.eu/en/medicines/national-registers-authorised-medicines. (Accessed 10/14/2022) (in Russian)
- National Agency for the Safety of Medicines and Health Products (ANSM). Directory of drugs [Электронный ресурс]. URL: http://agence-prd.ansm.sante.fr/php/ecodex/index.php#result. (Дата обращения 14.10.2022) (in Russian)
- Italian Medicines Agency (IMA). Access to medicinal products. [Электронный ресурс]. URL: https://www.aifa.gov.it/en/web/guest/accesso-al-farmaco . (Дата обращения 14.10.2022) (in Russian)
- Pharm’ Net: The Algerian Drug Repository [Электронный ресурс]. URL: https://pharmanet-dz.com/recherche.aspx?q=precylan. (Дата обращения 14.10.2022) (in Russian)
- Algeria press service, Publication of the list of drugs dispensed in pharmacies. Posted On: Tuesday, December 14, 2021: [Электронный ресурс]. URL: https://www.aps.dz/sante-science-technologie/132690-industrie-pharmaceutical-publication-de-la-liste-des-medicaments-exemptions-en-pharmacy (Дата обращения 14.10.2022) (in Russian)
- Libyan Essential Medicines List (LEML)- 1st Edition. Manual and Guideline. Source : Govt. Libya. Posted: 15 Nov 2022. Originally published: 30 Apr 2019. [Электронный ресурс]. URL: https://reliefweb.int/report/libya/libyan-essential-medicines-list-1st-edition. (Дата обращения 14.10.2022) (in Russian)
- Saudi Food and Drug Authority (SFDA): Drugs list. [Электронный ресурс]. URL: https://www.sfda.gov.sa/en/drugs-list. (Дата обращения 14.10.2022) (in Russian)
- KlassInform – all codes of all-Russian classifiers: [Electronic resource]. URL: https://classinform.ru/atc-classifikatcija/kod-atc-a07b-kishechnye-adsorbentyfurazolidon.html. (Accessed 10/14/2022) (in Russian)
- ATC/DDD Index 2022: [Electronic resource] WHO Collaborating Center for Drug Statistics Methodology. URL: http://www.whocc.no/ (Accessed 10/13/2022) (in Russian)
- leading causes of death in the world [Electronic resource] / World. org. Health (WHO). Geneva, 2014. Access mode: http://www.who.int/mediacentre/factsheets/fs310/ru (in Russian)
- Yuteka: [Electronic resource]. URL: https://uteka.ru/. (Accessed 10/14/2022) (in Russian)
- Logiciel de gestion medicale: [Electronic resource]. URL: https://medicament-dz.com/search?criteria=PRECYLAN. (Accessed 10/14/2022) (in Russian)
- Repertoire des medicaments – Medzai.net, © 2016–2019: [Electronic resource]. URL: https://medzai.net/fr/contact.php (Accessed 10/14/2022) (in Russian)
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