On the issue of standardization of wild chicory grass
- Authors: Saybel O.L.1, Konyaeva E.A.1, Radimich A.I.1, Rendyuk T.D.2, Dargaeva T.D.1
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Affiliations:
- All-Russian Research Institute of Medicinal and Aromatic Plants
- Sechenov First Moscow State Medical University (Sechenov University)
- Issue: Vol 72, No 6 (2023)
- Pages: 32-39
- Section: Pharmaceutical chemistry and pharmacognosy
- URL: https://journals.eco-vector.com/0367-3014/article/view/624376
- DOI: https://doi.org/10.29296/25419218-2023-06-05
- ID: 624376
Cite item
Abstract
Introduction. Expansion of the nomenclature of medicinal plant raw materials for creation of effective medicines on their basis is one of the priority directions of pharmaceutical science. Among representatives of the native flora, common chicory is of interest for study.
Objective: This article is devoted to the study of chicory herb proposed as a raw material for the production of medicines.
Results. As a result of pharmacognostic study of chicory herb samples, authenticity criteria (morphological and anatomical signs, thin layer chromatography) and quality indicators have been established. On the basis of the analysis of experimental batches of raw materials the norms of numerical indicators have been determined. A method of quantitative determination of the content of active substances has been developed.
Conclusion. The proposed quality criteria are included in the draft pharmacopoeial article on a new type of medicinal plant raw material Chicory herba.
Keywords
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About the authors
Olga Leonidovna Saybel
All-Russian Research Institute of Medicinal and Aromatic Plants
Author for correspondence.
Email: olster@mail.ru
ORCID iD: 0000-0001-8059-5064
Doctor of Pharmaceutical Sciences, Head of the Center for Chemistry and Pharmaceutical Technology, All-Russian Research Institute of Medicinal and Aromatic Plants
Russian Federation, Grina str., 7/2, Moscow, 117216Elena Anatolyevna Konyaeva
All-Russian Research Institute of Medicinal and Aromatic Plants
Email: lencon64@mail.ru
ORCID iD: 0000-0002-2154-3755
Senior Researcher at the Department of Chemistry of Natural Compounds, All-Russian Research Institute of Medicinal and Aromatic Plants
Russian Federation, Grina str., 7/2, Moscow, 117216Andrey Ivanovich Radimich
All-Russian Research Institute of Medicinal and Aromatic Plants
Email: vilarnii.radimich@mail.ru
ORCID iD: 0000-0002-1139-8902
Senior Researcher at the Department of Chemistry of Natural Compounds, All-Russian Research Institute of Medicinal and Aromatic Plants
Russian Federation, Grina str., 7/2, Moscow, 117216Tamara Danilovna Rendyuk
Sechenov First Moscow State Medical University (Sechenov University)
Email: rendyuk_t_d@staff.sechenov.ru
ORCID iD: 0000-0002-0359-3847
PhD of Pharmaceutical Sciences, Associate Professor, Department of Pharmaceutical Natural Sciences, Institute of Pharmacy, Sechenov University
Russian Federation, Trubetskaya str., 8/2, Mosсow, 119991Tamara Darizhapovna Dargaeva
All-Russian Research Institute of Medicinal and Aromatic Plants
Email: vilarnii@mail.ru
ORCID iD: 0000-0002-0722-9479
Doctor of Pharmaceutical Sciences, Professor, Chief Researcher at the Department of Chemistry of Natural Compounds, All-Russian Research Institute of Medicinal and Aromatic Plants
Russian Federation, Grina str., 7/2, Moscow, 117216References
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