Surgical Treatment of Talus Osteochondral Lesions with Platelet-Rich Plasma

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Wide application of cell therapy particularly platelet enriched plasma (PRP) in modern orthopaedics enabled to improved treatment results in certain orthopaedic diseases and injury consequences. Treatment results for 7 patients (2 men and 5 women) with osteochondral lesions of talus (OLT) are presented. Mean age of patients was 26 years, mean duration of disease — 4 years. By Brendt and Harty roentgenologic classification I—II degree of OLT was diagnosed in 1 and III—IV degree — in 6 patients. In all patients mosaic chondroplasty of talus with implantation of PRP gel was performed. Postoperatively mean AOFAS index raised from 53 to 92. Follow up period made up around 2 years.

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Хирургическое лечение остеохондральных поражений таранной кости с использованием плазмы, обогащенной тромбоцитами


  1. Berndt A.L., Harty M. Transcondylar fractures (osteochondritis dissecans) of the talus. J. Bone Joint Surg. Am. 1959; 41: 988-1020.
  2. Clanton T.O., DeLee J.C. Osteochondritis dissecans. History, pathophysiology, and current treatment concepts. Clin. Orthop. Relat. Res. 1982; 167: 50-64.
  3. Tol J.L., Struijs P.A., Bossuyt P.M., Verhagen R.A., van Dijk C.N. Treatment strategies in osteochondral defects of the talar dome: a systematic review. Foot Ankle Int. 2000; 21 (2): 119-26.
  4. Pettine K.A., Morrey B.F. Osteochondral fractures of the talus. A long-term follow-up. J. Bone Joint Surg. Br. 1987; 69 (1): 89-92.
  5. Zengerink M., Struijs P.A., Tol J.L., van Dijk C.N. Treatment of osteochondral lesions of the talus: a systematic review. Knee Surg. Sports Traumatol. Arthrosc. 2010; 18 (2): 238-46.
  6. Anitua E, Sánchez M., Nurden A.T., Zalduendo M.M., de la Fuente M., Azofra J., Andía I. Platelet-released growth factors enhance the secretion of hyaluronic acid and induce hepatocyte growth factor production by synovial fibroblasts from arthritic patients. Rheumatology (Oxford). 2007; 46 (12): 1769-72.
  7. Arnoczky S.P., Anderson L., Fanelli G., Sherwin S.W., Mishra A., Sgaglione N.A. The role of platelet-rich plasma in connective tissue repair. Orthopedics Today. 2009; 26: 29.
  8. Кесян Г.А., Берченко Г.Н., Уразгильдеев Р.З., Микелаишвили Д.С. Сочетанное применение обогащенной тромбоцитами аутоплазмы и биокомпозиционного материала Коллапан в комплексном лечении больных с длительно несрастающимися переломами и ложными суставами длинных костей конечностей. Вестник травматологии и ортопедии им. Н.Н. Приорова. 2011; 2: 26-32.
  9. Микелаишвили Д.С. Применение аутотромбоцитарных факторов роста и коллапана при оперативном лечении диафизарных переломов: Автореф. дис.. канд. мед. наук. М., 2012.
  10. Кесян Г.А., Берченко Г.Н., Уразгильдеев Р.З., Нахапетян Т.Г. Лечение разрывов ахиллова сухожилья. Вестник травматологии и ортопедии им. Н.Н. Приорова. 2011; 4: 80-86.
  11. Dahm D.L., Manzanares J. Osteochondral lesions of the talar dome. Orthopaedic surgery board review manual. Vol. 7, part 2. 2001.



Abstract: 115


CrossRef: 1

  1. Silant’Eva TA, Krasnov VV. Effect of Autologous Plasma, Ascorbic Acid and Glucose Local Infusions on Pelvic Fracture Healing in Experiment. Vestnik travmatologii i ortopedii imeni N.N. Priorova. 2014;(1):45. doi: 10.32414/0869-8678-2014-1-45-51


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