Aspects of surgical treatment in a petient with Isaac’s syndrome

Cover Page

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access


This article presents a clinical case demonstrating the correction treatment of the lower extremities in a patient with Issac’s syndrome, as well as the results of ankle surgery and successful post-surgery rehabilitation. The high efficiency of surgery as a treatment method was confirmed.

Full Text

Restricted Access

About the authors

Nikolay A. Koryshkov

Yaroslavl State Medical University

Author for correspondence.
ORCID iD: 0000-0003-4465-2660
SPIN-code: 9258-6260

PhD, associate professor

Russian Federation, 5 Revolutionnaya, Yaroslavl, 150000

Lyudmila K. Mikhailova

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

SPIN-code: 8866-0410

PhD, professor, traumatologist-orthopedist

Russian Federation, Moscow

Artur S. Khodzhiev


SPIN-code: 9960-8290

Cand. Sci. (Med.), traumatologist-orthopedist

Uzbekistan, Tashkent

Igor I. Litvinov

Yaroslavl State Medical University

ORCID iD: 0000-0003-1135-4376
SPIN-code: 2730-1365

PhD, associate professor

Russian Federation, 5 Revolutionnaya, Yaroslavl, 150000


  1. Ponomarev VV. Redkie nevrologicheskie sindromy i bolezni: nablyudeniya iz praktiki. Saint Petersburg: Foliant; 2005. P. 41–48. (In Russ.)
  2. Yakhno NN, editor. Bolezni nervnoi sistemy. Vol. 1. Moscow: Meditsina; 2005. P. 637–638. (In Russ.)
  3. Dhand UK. Isaacs’s syndrome: clinical and electrophysiological response to gabapentin. Muscle Nerve. 2006;34(5):646–650. doi: 10.1002/mus.20591
  4. Luk’yanov MV, Khvorostina AV, Isaeva NA. Diagnosis and treatment of Isaac’s syndrome. Nevrologicheskii zhurnal. 2003;8(6):21–26. (In Russ.)
  5. Ponomarev VV. Autoimmunnye zabolevaniya v nevrologii. Minsk: Belaruskaya navuka; 2010. P. 104–109. (In Russ.)
  6. Meinck HM. Stiff-Man syndrome. In: Lang F, editor. Encyclopedia of molecular mechanisms of disease. Berlin: Springer; 2009. P. 540–542.
  7. Dumitru D, editor. Electrodiagnostic medicine. St. Louis: Mosby; 1995. P. 501–503.
  8. Falace A, Striano P, Manganelli F, et al. Inherited neuromyotonia: a clinical and genetic study of a family. Neuromuscul Disord. 2007;17(1):23–27. doi: 10.1016/j.nmd.2006.09.014
  9. Maddison P. Neuromyotonia. Clin Neurophysiol. 2006;117(10):2118–2127. doi: 10.1016/j.clinph.2006.03.008
  10. Panagariya A, Kumar H, Mathew V, Sharma B. Neuromyotonia: clinical profile of twenty cases from northwest India. Neurol India. 2006;54(4):382–386. doi: 10.4103/0028-3886.28110

Supplementary files

Supplementary Files
1. Fig. 1. Feet before surgery, the patient can only rely on the forefoot. A constant exhausting tension in the muscles of legs and feet was observed

Download (74KB)
2. Fig. 2. Radiographs presenting the vicious position of feet and ankle joints, osteoporosis, talonavicular joints subluxation

Download (97KB)
3. Fig. 3. Computed tomogram scan demonstrating defective positioning of feet and ankle joints

Download (82KB)
4. Fig. 4. Patient’s handmade orthosis for training gait in the preoperative period used for about 8 months

Download (81KB)
5. Fig. 5. Postoperative X-ray of the right foot and ankle, the foot became loaded in the correct position with the load distributed over the entire plantar surface

Download (66KB)
6. Fig. 6. Postoperative radiography of the left foot and ankle. The result is similar to the previous intervention

Download (69KB)
7. Fig. 7. Long-term result, 5 years after surgery.

Download (125KB)



Abstract: 81

PDF (Russian): 2


Article Metrics

Metrics Loading ...



  • There are currently no refbacks.

Copyright (c) 2021 Eco-Vector

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies