Earlier diagnosis of the heart contusions for patients with closed chest injury
- Authors: Stark E.A.
- Section: SCIENTIFIC REVIEWS
- Submitted: 02.06.2024
- Accepted: 14.06.2024
- Published: 30.10.2025
- URL: https://journals.eco-vector.com/0869-8678/article/view/633098
- DOI: https://doi.org/10.17816/vto633098
- ID: 633098
Cite item
Abstract
Closed chest injury (CCI) is one of the most urgent problems of traumatology and cardiology. The most severe and life-threatening injuries to the heart, including contusion, are those caused by a CCI. In peacetime, cardiac contusion arises from mechanical impact on the chest. Most often, this situation occurs during high-speed car accidents at the moment of sudden braking when a car collides with an obstacle and, as a result, the chest collides with the steering wheel or steering column. Timely diagnosis and treatment of cardiac contusions are the key to reducing complications in CCI. To study the possibilities of various diagnostic approaches in patients with closed heart contusions, analyzing the literature data of domestic and foreign studies. Having made a review based on data from domestic and foreign studies, we have established that on present day there is not any diagnosis method which does not have a high probability of determining a heart injury probability for degree of heat injury in early stage after trauma. The clinical picture of a heart contusion is also not specific, which does not allow identifying this type of injury in most cases. This leads to a lack of timely and adequate therapy and the development of various complications, including fatal ones. The only reliable method of diagnosing a heart contusion today is a histological examination of the myocardium, which cannot be performed during life. The search for new methods for the timely diagnosis of cardiac contusions is an urgent interdisciplinary task. The article provides a justification for the possibility of determining markers of secondary mitochondrial dysfunction of cardiomyocytes for the early diagnosis of closed contusions of the heart.
Full Text
References
- Gubaidullin MI. Epidemiology of road traffic accident and trafic injury (review of domestic and foreign literature). Vestnic of Yuzhno-Ural'skogo Gosudarstvennogo Universiteta. 2010;(19);89–93. EDN: MUFAWF
- Brewer B, Zarzaur BL. Cardiac Contusions. Current Trauma Reports. 2015;1:232–236. doi: 10.1007/s40719-015-0031-x
- Novoselov VP, Savchenko SV, Porvin AN, Koshlyak DA. Ultrastructural disorders of transendothelial transfer of substances in experimental injury of the heart. Vestnic of forensic medicine. 2015;4(1):16–18. EDN: TVSVGT
- Sybrandy KC, Cramer MJM, Burgersdijk C. Diagnosing cardiac contusion: old wisdom and new insights. Heart. 2003;89(5):485–489. doi: 10.1136/heart.89.5.485
- Hill G, Davies K. Blunt chest trauma: a challenge to accident and emergency nurses. Accid Emerg Nurs. 2002;10:197–204. doi: 10.1016/s0965-2302(02)00126-1
- Priymak AB, Korpacheva OV, Zolotov AN. Unresolved issues of pathogenesis of myocardial contusion. Vestnik SurGU. Meditsina. 2020;(2):66–72. doi: 10.34822/2304-9448-2020-2-66-72 EDN: EOLTXJ
- Nagy KK, Krosner SM, Roberts RR, et al. Determining which patients require evaluation for blunt cardiac injury following blunt chest trauma. World J Surg. 2001;25(1):108–11. doi: 10.1007/s002680020372
- Novoselov VP, Savchenko SV, Romanova EA, Cymmerman VG., Patomorphological aspects of heart injury. Novosibirsk: Nauka; 2002. 168 р. (In Russ.)
- Novoselov VP, Savchenko SV, Porvin AN, et al. Ultrastructural characteristics of the moocardial for mechanical injury of the heart in an experiment. Sibirskij Nauchnyj Medicinskij Zhurnal. 2016;36(2). (In Russ.)
- Lesnefsky EJ, Chen Q, Tandler B, Hoppel CL. Mitochondrial Dysfunction and Myocardial Ischemia-Reperfusion: Implications for Novel Therapies. Annu Rev Pharmacol Toxicol. 2017;57:535–565. doi: 10.1146/annurev-pharmtox-010715-103335
- Qiu Z, Wei Y, Song Q, et al. The Role of Myocardial Mitochondrial Quality Control in Heart Failure. Review article. Front Pharmacol. 2019;10:1404. doi: 10.3389/fphar.2019.01404
- Rashed MS. Clinical applications of tandem mass spectrometry: ten years of diagnosis and screening for inherited metabolic diseases. J Chromatogr B Biomed Sci Appl. 2001;758(1):27–48. doi: 10.1016/s0378-4347(01)00100-1
- Bon LI, Maksimovich NE. Role of mitochondria in cells energetic and characterizing its molecular markers. Orenburg Medical Bulletin. 2019;VII(1):47–52. EDN: ZAQJHN
- Krikunova OV, Viskov RV. Cardiac troponins in medical practice. Moscow: MEDpress-inform; 2016. 240 р. (In Russ.)
- Kyriazidis IP, Jakob DA, Vargas JAH, et al. Accuracy of diagnostic tests in cardiac injury after blunt chest trauma: a systematic review and meta-analysis. World J Emerg Surg. 2023;18(1):36. doi: 10.1186/s13017-023-00504-9
- Bertinchant JP, Polge A, Mohty D, et al. Evaluation of Incidence, Clinical Significance, and Prognostic Value of Circulating Cardiac Troponin I and T Elevation in Hemodynamically Stable Patients with Suspected Myocardial Contusion after Blunt Chest Trauma. J Trauma. 2000;48(5):924–31. doi: 10.1097/00005373-200005000-00018
- Salim A, Velmahos GC, Jindal A, et al. Clinically significant blunt cardiac trauma: role of serum troponin levels combined with electrocardiographic findings. J Trauma. 2001;50(2):237–43. doi: 10.1097/00005373-200102000-00008
- Helling TS, Duke P, Beggs CW, Crouse LJ. A prospective evaluation of 68 patients suffering blunt chest trauma for evidence of cardiac injury. J Trauma. 1989;29(7):961–5; discussion 965–6. doi: 10.1097/00005373-198907000-00009
- Hiatt JR, Yeatman LA Jr, Child JS. The value of echocardiography in blunt chest trauma. J Trauma. 1988;28(7):914–22. doi: 10.1097/00005373-198807000-00003
- Novoselov VP, Savchenko SV, Voronovskaya MV. Problems of expert assessment of the severity of harm to health in case of heart contusions in the case of examination of living persons. Sibirskij Nauchnyj Medicinskij Zhurnal. 2008;(1):65–67. (In Russ.)
- Korpacheva OV. Mechanisms of formation of myocardial dysfunction and metabolic cytoprotection in heart injury [dissertation]. Omsk, 2009. 230 р. EDN: NQLMUR
- Sybrandy KC, Cramer MJM, Burgersdijk C. Diagnosing cardiac contusion: old wisdom and new insights. Heart. 2003;89(5):485–489. doi: 10.1136/heart.89.5.485
- Kuzmin АY. Early diagnosis, intensive care, determination of surgical tactics in patients with severe combined trauma accompanied by a bruised heart. [dissertation abstract]. St. Petersburg, 2009. 22 р. EDN: NLGUJF
- Lee C-H, Tsai W-C, Kan C-D, Lin L-J. Acute aortic valve rupture after blunt chest trauma and cardiac catheterization. Injury Extra. 2005;36(12):575–577. doi: 10.1016/j.injury.2005.05.041
- Novoselov VP, Savchenko SV. Expert diagnosis of a heart injury: monograph; Novosibirsk State Medical University. Tomsk: STT; 2021. 234 p. (In Russ.)
- Vasyuk YA, Kulikov KG, Kudryakov ON, Krikunova OV, Sadulaeva IA. Secondary mitochondrial dysfunction in acute coronary syndrome. Rational Pharmacotherapy in Cardiology. 2007;3(1):41–47. doi: 10.20996/1819-6446-2007-3-1-41-47 EDN: JSAGYH
- Koshlyak DA. Morpho-histochemical and ultrastructural changes of the myocardium in heart injury. [dissertation abstract]. Novosibirsk, 2008. 19 р. EDN: NKPGPP
- Mammadov IS. Laboratory diagnostics of metabolic disorders of amino acids, organic acids and acylcarnitines. Method. Handbook. Moscow; 2008. (In Russ.)
- Mammadov IS. Coenzyme Q10 deficiency: clinical and genetic variants, ways of diagnosis and therapy. Method. Stipend. Moscow; 2009. (In Russ.)
Supplementary files

