Renander–Müller disease: current state of the problem



Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

This scientific data review addresses the issues of diagnosis and treatment of avascular necrosis of the sesamoid bones, also known as Renander–Müller disease. This condition is relatively rare and predominantly affects physically active young individuals. The combination of these two factors contributes to diagnostic challenges, persistent functional impairment, and a high rate of disability. No publications on this condition were found in Russian. The scientific data search was conducted using the PubMed, Medline, Scopus, Google Scholar, and eLIBRARY databases. A total of 47 publications were included in the review. The search was performed using the following keywords, their derivatives, and combinations in the titles and abstracts: avascular necrosis of the sesamoid, sesamoid AVN, hallucial sesamoid disorders, Renander–Müller disease, osteonecrosis, sesamoidectomy, and sesamoid. The initial screening for inclusion criteria was conducted using the titles and abstracts, followed by full-text analysis of the selected articles. Sources without accessible full-text versions were excluded from the analysis.

Full Text

Restricted Access

About the authors

Alexander V. Skrebtsov

Yudin City Clinical Hospital of the Moscow Health Department

Author for correspondence.
Email: Skrebtsovalex@mail.ru
ORCID iD: 0000-0002-1418-3368
SPIN-code: 3682-4569
Russian Federation, Moscow

Viktor G. Protsko

Yudin City Clinical Hospital of the Moscow Health Department; Peoples’ Friendship University of Russia

Email: 89035586679@mail.ru
ORCID iD: 0000-0002-5077-2186
SPIN-code: 4628-7919

MD, Dr. Sci. (Medicine), Professor

Russian Federation, Moscow; Moscow

Nikolay V. Zagorodniy

Peoples’ Friendship University of Russia; Priorov National Medical Research Center of Traumatology and Otrhopaedics

Email: zagorodniy51@mail.ru
ORCID iD: 0000-0002-6736-9772
SPIN-code: 6889-8166

MD, Dr. Sci. (Medicine), Professor, Corresponding member of the Russian Academy of Sciences

Russian Federation, Moscow; Moscow

Vladimir V. Skrebtsov

Yudin City Clinical Hospital of the Moscow Health Department

Email: Skrebtsov@mail.ru
ORCID iD: 0000-0003-0833-6628
SPIN-code: 6002-7102

MD, Cand. Sci. (Medicine)

Russian Federation, Moscow

Vsevolod O. Kalensky

Yudin City Clinical Hospital of the Moscow Health Department

Email: vsevolod.kalenskiy@gmail.com
ORCID iD: 0000-0001-7088-3206
SPIN-code: 6412-8774

MD, Cand. Sci. (Medicine)

Russian Federation, Moscow

Sargon K. Tamoev

Yudin City Clinical Hospital of the Moscow Health Department

Email: Sargonik@mail.ru
ORCID iD: 0000-0001-8748-0059
SPIN-code: 2986-1390

MD, Cand. Sci. (Medicine)

Russian Federation, Moscow

Daniil G. Agafonov

Saint-Petersburg State Research Institute of Phthisiopulmonology

Email: ortho_spot@bk.ru
ORCID iD: 0009-0002-5957-1548
SPIN-code: 9001-9773
Russian Federation, St. Petersburg

References

  1. Stracciolini A, Dahlberg BW, Quinn B, Sugimoto D, Stein C. Sesamoid injuries in pediatric and adolescent athletes presenting to sports medicine clinic. Orthop J Sports Med. 2019;7(3_suppl):2325967119S0018. doi: 10.1177/2325967119s00183
  2. Renander A. Two Cases of Typical Osteochondropathy of the Medial Sesamoid Bone of the First Metatarsal. Acta Radiol. 1924;3(6):521–527. doi: 10.1177/028418512400300607
  3. Nwawka OK, Hayashi D, Diaz LE, et al. Sesamoids and accessory ossicles of the foot: Anatomical variability and related pathology. Insights Imaging. 2013;4(5):581–593. doi: 10.1007/s13244-013-0277-1
  4. Fan R, Lychagin AV, Bobrov DS. To Study the Surgical Treatment of Stress Fracture and Avn of Sesamoid Bone. J Nat Sci Biol Med. 2023;14(2):189–197. doi: 10.4103/jnsbm.JNSBM_14_2_14
  5. Van Hal ME, Keene JS, Lange TA, Clancy WG Jr. Stress fractures of the great toe sesamoids. Am J Sports Med. 1982;10(2):122–128. doi: 10.1177/036354658201000212
  6. Julsrud ME. Osteonecrosis of the tibial and fibular sesamoids in an aerobics instructor. The Journal of Foot and Ankle Surgery. 1997;36(1):31–35. doi: 10.1016/S1067-2516(97)80008-7
  7. Dharap AS, Al-Hashimi H, Kassab S, Abu-Hijleh MF. Incidence and ossification of sesamoid bones in the hands and feet: A radiographic study in an Arab population. Clinical Anatomy. 2007;20(4):416–423. doi: 10.1002/ca.20378
  8. Sun T, Zhao H, Wang L, Wu W. Partite hallux sesamoid bones: Relationship with sesamoid bones at other metatarsophalangeal joints. Anat Rec. 2018;301(1):34–38. doi: 10.1002/ar.23696
  9. Schein AJ, Skalski MR, Patel DB, et al. Turf toe and sesamoiditis: what the radiologist needs to know. Clin Imaging. 2015;39(3):380–389. doi: 10.1016/j.clinimag.2014.11.011
  10. Lombard C, Gillet R, Rauch A, et al. Hallux sesamoid complex imaging: a practical diagnostic approach. Skeletal Radiol. 2020;49(12):1889–1901. doi: 10.1007/s00256-020-03507-8
  11. Chamberland PD, Smith JW, Fleming LL. The blood supply to the great toe sesamoids. Foot Ankle. 1993;14(8):435–442. doi: 10.1177/107110079301400802
  12. Pretterklieber ML, Wanivenhaus A. The Arterial Supply of the Sesamoid Bones of the Hallux: The Course and Source of the Nutrient Arteries as an Anatomical Basis for Surgical Approaches to the Great Toe. Foot Ankle. 1992;13(1):27–31. doi: 10.1177/107110079201300105
  13. Bickley MKJ, Li J, Mackay ND, Chapman AWP. Avascular necrosis of the foot and ankle: aetiology, investigation and management. Orthop Trauma. 2023;37(1):40–48. doi: 10.1016/j.mporth.2022.11.006
  14. Robertson GAJ, Goffin JS, Wood AM. Return to sport following stress fractures of the great toe sesamoids: a systematic review. Br Med Bull. 2017;122(1):135–149. doi: 10.1093/bmb/ldx010
  15. Taylor CF, Butler M, Parsons SW. Problems Associated with the Excision of the Hallux Sesamoids. Foot Ankle Clin. 2014;19(3):425–436. doi: 10.1016/j.fcl.2014.06.014
  16. Toussirot É, Jeunet L, Michel F, Kantelip B, Wendling D. Avascular necrosis of the hallucal sesamoids update with reference to two case-reports. Joint Bone Spine. 2003;70(4):307–309. doi: 10.1016/S1297-319X(03)00061-7
  17. Sanders TG, Rathur SK. Imaging of painful conditions of the hallucal sesamoid complex and plantar capsular structures of the first metatarsophalangeal joint. Radiol Clin North Am. 2008;46(6):1079–1092, vii. doi: 10.1016/j.rcl.2008.09.001
  18. Toussirot É, Jeunet L, Michel F, Kantelip B, Wendling D. Ostéonécrose aseptique des sésamoïdes métatarsiens ou maladie de Renander: aspects actuels à propos de 2 cas. Rev Rhum. 2003;70:609–612. doi: 10.1016/S1169-8330(03)00144-3
  19. Sims AL, Kurup H V. Painful sesamoid of the great toe. World J Orthop. 2014;5(2):146–150. doi: 10.5312/wjo.v5.i2.146
  20. Barral CM, Félix AM, Magalhães LN, Carvalho LA, Machado FS. The bone scintigraphy as a complementary exam in the complementary exam in the diagnosis of the avascular necrosis of the sesamoid. Revista Brasileira de Ortopedia (English Edition). 2012;47(2):241–245. doi: 10.1016/s2255-4971(15)30093-8
  21. Boike A, Schnirring-Judge M, McMillin S. Sesamoid Disorders of the First Metatarsophalangeal Joint. Clin Podiatr Med Surg. 2011;28(2):269–285. doi: 10.1016/j.cpm.2011.03.006
  22. Williams G, Kenyon P, Fischer B, Platt S. An Atypical Presentation of Hallucial Sesamoid Avascular Necrosis: A Case Report. The Journal of Foot and Ankle Surgery. 2009;48(2):203–207. doi: 10.1053/j.jfas.2008.11.004
  23. Wang CJ, Cheng JH, Huang CC, Yip HK, Russo S. Extracorporeal shockwave therapy for avascular necrosis of femoral head. International Journal of Surgery. 2015;24:184–187. doi: 10.1016/j.ijsu.2015.06.080
  24. Kertzman P, Császár NBM, Furia JP, Schmitz C. Radial extracorporeal shock wave therapy is efficient and safe in the treatment of fracture nonunions of superficial bones: a retrospective case series. J Orthop Surg Res. 2017;12(1):164. doi: 10.1186/s13018-017-0667-z
  25. Saxena A, Yun A, Patel R, Gerdesmeyer L, Maffulli N. Radial Soundwave for Sesamoidopathy in Athletes: A Pilot Study. The Journal of Foot and Ankle Surgery. 2016;55(6):1333–1335. doi: 10.1053/j.jfas.2016.07.024
  26. Thompson D, Malliaropoulos N, Padhiar N. Sesamoid osteonecrosis treated with radial extracorporeal shock wave therapy. BMJ Case Rep. 2017;2017:bcr2017219191. doi: 10.1136/bcr-2017-219191
  27. Honda Saito G, Sakaki M, Ng S, Corsato M, Fernandes T. Conservative approach to avascular necrosis of the hallucial sesamoid: case report. Rev ABTPé. 2016;10:100–103.
  28. Le HM, Stracciolini A, Stein CJ, Quinn BJ, Jackson SS. Platelet rich plasma for hallux sesamoid injuries: a case series. Phys Sportsmed. 2022;50(2):181–184. doi: 10.1080/00913847.2021.1964006
  29. Shimozono Y, Hurley ET, Brown AJ, Kennedy JG. Sesamoidectomy for Hallux Sesamoid Disorders: A Systematic Review. The Journal of Foot and Ankle Surgery. 2018;57(6):1186–1190. doi: 10.1053/j.jfas.2018.03.044
  30. Ozkoc G, Akpınar S, Ozalay M, et al. Hallucal Sesamoid Osteonecrosis: An Overlooked Cause of Forefoot Pain. J Am Podiatr Med Assoc. 2005;95:277–280. doi: 10.7547/0950277
  31. Pearson JM, Moraes LVM, Paul KD, et al. Is Fibular Sesamoidectomy a Viable Option for Sesamoiditis? A Retrospective Study. Cureus. 2019;11(6):e4939. doi: 10.7759/cureus.4939
  32. McBride ED. The McBride bunion hallux valgus operation. J Bone Joint Surg Am. 1967;49(8):1675–1683.
  33. Bichara DA, Henn RF 3rd, Theodore GH. Sesamoidectomy for Hallux Sesamoid Fractures. Foot Ankle Int. 2012;33(9):704–706. doi: 10.3113/FAI.2012.0704
  34. Nayfa TM, Sorto LA Jr. The incidence of hallux abductus following tibial sesamoidectomy. J Am Podiatry Assoc. 1982;72(12):617–620. doi: 10.7547/87507315-72-12-617
  35. Alshryda S, Lou T, Faulconer ER, Adedapo AO. Adolescent Hallux Valgus Deformity with Bilateral Absence of the Hallucal Sesamoids: A Case Report. The Journal of Foot and Ankle Surgery. 2012;51(1):80–82. doi: 10.1053/j.jfas.2011.09.003
  36. Mehtar M, Saragas NP, Ferrao PN. Functional and patient reported outcomes following lateral hallucal sesamoidectomy. The Foot. 2020;43:101656. doi: 10.1016/j.foot.2019.101656
  37. Canales MB, DeMore III M, Bowen MF, Ehredt Jr. DJ, Razzante MC. Fact or Fiction? Iatrogenic Hallux Abducto Valgus Secondary to Tibial Sesamoidectomy. The Journal of Foot and Ankle Surgery. 2015;54(1):82–88. doi: 10.1053/j.jfas.2014.09.024
  38. Downey MS, Lawrence GA. Digital and sesamoid fractures. In: Southerland JT, Vickers DF, Boberg JS, et al., editors. McGlamry’s Comprehensive Textbook of Foot and Ankle Surgery. Lippincott Williams & Wilkins, Philadelphia; 2013: 1629–1645.
  39. Chan PK, Lui TH. Arthroscopic fibular sesamoidectomy in the management of the sesamoid osteomyelitis. Knee Surg Sports Traumatol Arthrosc. 2006;14(7):664–667. doi: 10.1007/s00167-005-0030-5.
  40. Nakajima K. Arthroscopic Sesamoidectomy for Hallux Sesamoid Disorders. The Journal of Foot and Ankle Surgery. 2022;61(1):175–180. doi: 10.1053/j.jfas.2021.06.004
  41. Shin EH, Kwon WH, Dujela MD, Kim BS. Arthroscopic Synovectomy and Excision of a Sesamoid in the Management of an Atypical Presentation of Avascular Necrosis of Bone: A Case Report. The Journal of Foot and Ankle Surgery. 2020;59(3):594–597. doi: 10.1053/j.jfas.2019.09.026
  42. Lee S, James WC, Cohen BE, Davis WH, Anderson RB. Evaluation of Hallux Alignment and Functional Outcome after Isolated Tibial Sesamoidectomy. Foot Ankle Int. 2005;26(10):803–809. doi: 10.1177/107110070502601003
  43. Aper RL, Saltzman CL, Brown TD. The effect of hallux sesamoid excision on the flexor hallucis longus moment arm. Clin Orthop Relat Res. 1996;(325):209–217. doi: 10.1097/00003086-199604000-00025
  44. Tabatabaee RM, Saberi S, Parvizi J, Mortazavi SMJ, Farzan M. Combining Concentrated Autologous Bone Marrow Stem Cells Injection With Core Decompression Improves Outcome for Patients with Early-Stage Osteonecrosis of the Femoral Head: A Comparative Study. J Arthroplasty. 2015;30(9):11–15. doi: 10.1016/j.arth.2015.06.022
  45. Arbeloa-Gutierrez L, Dean CS, Chahla J, Pascual-Garrido C. Core Decompression Augmented With Autologous Bone Marrow Aspiration Concentrate for Early Avascular Necrosis of the Femoral Head. Arthrosc Tech. 2016;5(3):e615–e620. doi: 10.1016/j.eats.2016.02.009
  46. Shimozono Y, Seow D, Kennedy JG. Concentrated Bone Marrow Aspirate Injection for Hallux Sesamoid Disorders. Foot Ankle Orthop. 2019;4(4):2473011419S0039. doi: 10.1177/2473011419s00390
  47. Shimozono Y, Seow D, Kennedy JG. Concentrated Bone Marrow Aspirate Injection for Hallux Sesamoid Disorders. The Journal of Foot and Ankle Surgery. 2022;61(3):633–636. doi: 10.1053/j.jfas.2021.10.027
  48. McIntyre JA, Jones IA, Danilkovich A, C. Thomas Vangsness J. The Placenta: Applications in Orthopaedic Sports Medicine. Am J Sports Med. 2018;46(1):234–247. doi: 10.1177/0363546517697682
  49. Scala VA, Kikuchi CK. Sesamoid Avascular Necrosis and Stress Fracture Treated with Core Decompression and Biologic Augmentation. Hawaii J Health Soc Welf. 2022;81(3 Suppl 1):16–18.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download
2. Fig. 1. MRI of the foot of a patient with a confirmed diagnosis of Renander-Müller disease: a hypointense area in the structure of the sesamoid bone, which corresponds to an area of necrosis with the presence of a hypointense signal from the surrounding soft tissues, which corresponds to their swelling. The patient's permission to publish the image has been obtained.

Download (97KB)
Indexing metadata

Copyright (c) Eco-Vector


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77-76249 от 19.07.2019.