Email this article Complex Treatment of Patients with Osteoporosis Complicated by Vertebral Bodies Fractures
- Authors: Astapenkov D.S.1, Astapenkov DS1
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- Issue: Vol 17, No 3 (2010)
- Pages: 43-47
- Section: Articles
- URL: https://journals.eco-vector.com/0869-8678/article/view/47931
- DOI: https://doi.org/10.17816/vto201017343-47
- ID: 47931
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Abstract
Assessment of the efficacy of complex approach to the treatment of patients with osteoporosis complicated by pathologic vertebral body fractures was performed. Eighty seven patients were randomized into 2 groups. Main group (62 women) obtained complex treatment. In control group (25 female patients) the treatment measures were of fragmental pattern.Prior to and after treatment all patients were clinically examined including evaluation of pain intensity by visual analog scale and life quality by Karnovski scale, assessment of fractures by Riggs, Kleekoper and Genant, frontal lumbar spine densitometry (Lunar Prodigy 3, General Electric), study of resorption marker β-Cross-Laps ELISA. It was shown that complex treatment of that group of patients was more effective as compared with fragmental treatment. Algorithm for choice of techniques to influence the structure and mineralization of bone tissue was suggested
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References
- Моисеев С.В. Антирезорбтивные средства и остеопоротические переломы //Клин. фармакол. и тер. - 2004. - Т. 13, N 1. - С. 5-7.
- Торопцова Н.В., Беневоленская Л.И. Постменопаузальный остеопороз - новые подходы к оценке эффективности антирезорбтивной терапии Миакальциком //Рус. мед. журн. - 2004. - Т. 12, N 2. - С. 120-123.
- Busse B. et al. Effects of strontium ranelate therapy after long term bisphosphonate treatment. Histo-morphometric and uXRF/EDX analysis of paired iliac crest bone biopsies in 15 patients //J. Bone. - 2007. - N 22. - P. 484-485.
- Croom K.F., Scott L.J. Intravenosus ibandronate in the treatment of osteoporosis //Drugs. - 2006. - N 66. - P. 1593-1601.
- Davidson M.R. Pharmacotherapeuticus for osteoporosis prevention and treatment //J. Midwifery Womens Health. - 2003. - N 48. - P. 39-52.
- Lippuner K.A. Medical treatment of vertebral osteoporosis //Eur. Spine J. - 2003. - N 12. - P. 132-141.
- Marquis P., Roux C., Diaz-Curiel M. Long-term beneficical effects of strontium ranelate on the quality of life in patients with vertebral osteoporosis (SOTI study) //Osteoporosis Int. - 2007. - N 18. - P. 123.
- Szpalski M.A., Gunzburg R.B. Vertebral osteoporotic compression fractures. - New York, 2003.
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).