Complex Treatment of Patients with Osteoporosis Complicated by Vertebral Bodies Fractures

Abstract


Assessment of the efficacy of complex approach to the treatment of patients with osteoporosis complicated by pathologic vertebral body fractures was performed. Eighty seven patients were randomized into 2 groups. Main group (62 women) obtained complex treatment. In control group (25 female patients) the treatment measures were of fragmental pattern.Prior to and after treatment all patients were clinically examined including evaluation of pain intensity by visual analog scale and life quality by Karnovski scale, assessment of fractures by Riggs, Kleekoper and Genant, frontal lumbar spine densitometry (Lunar Prodigy 3, General Electric), study of resorption marker β-Cross-Laps ELISA. It was shown that complex treatment of that group of patients was more effective as compared with fragmental treatment. Algorithm for choice of techniques to influence the structure and mineralization of bone tissue was suggested

References

  1. Моисеев С.В. Антирезорбтивные средства и остеопоротические переломы //Клин. фармакол. и тер. - 2004. - Т. 13, N 1. - С. 5-7.
  2. Торопцова Н.В., Беневоленская Л.И. Постменопаузальный остеопороз - новые подходы к оценке эффективности антирезорбтивной терапии Миакальциком //Рус. мед. журн. - 2004. - Т. 12, N 2. - С. 120-123.
  3. Busse B. et al. Effects of strontium ranelate therapy after long term bisphosphonate treatment. Histo-morphometric and uXRF/EDX analysis of paired iliac crest bone biopsies in 15 patients //J. Bone. - 2007. - N 22. - P. 484-485.
  4. Croom K.F., Scott L.J. Intravenosus ibandronate in the treatment of osteoporosis //Drugs. - 2006. - N 66. - P. 1593-1601.
  5. Davidson M.R. Pharmacotherapeuticus for osteoporosis prevention and treatment //J. Midwifery Womens Health. - 2003. - N 48. - P. 39-52.
  6. Lippuner K.A. Medical treatment of vertebral osteoporosis //Eur. Spine J. - 2003. - N 12. - P. 132-141.
  7. Marquis P., Roux C., Diaz-Curiel M. Long-term beneficical effects of strontium ranelate on the quality of life in patients with vertebral osteoporosis (SOTI study) //Osteoporosis Int. - 2007. - N 18. - P. 123.
  8. Szpalski M.A., Gunzburg R.B. Vertebral osteoporotic compression fractures. - New York, 2003.

Statistics

Views

Abstract - 23

Cited-By


Article Metrics

Metrics Loading ...

Refbacks

  • There are currently no refbacks.

Copyright (c) 2010 Eco-Vector



This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies