Vol XLV, No 1 (2013)

Articles
MENTAL HEALTH IN THE 21ST CENTURY. GENDER FEATURES OF POSTMODERN CULTURE
Korolenko T.P., Shpiks T.A.
Abstract
There have been analyzed peculiarities of postmodern society with revealing the most important factors, presenting increased demands to psychosocial adaptation. The flow of changes, constantly and rapidly appearing in the different spheres of life, leads to growth of pschic disorders of non-psychotic level and significantly changes state of the population mental health. Women in postmodern society are in the zone of the increased risk, what is connected with their bigger relation to the system of perceptions and evaluations, characteristic for the traditional culture. There were described causes of the most frequent in the postmodern society forms of psychotic disorders in women.
Neurology Bulletin. 2013;XLV(1):3-10
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BIOCHEMICAL CORRELATIONS OF CLINICAL AND PSYCHOPATHOLOGICAL DERANGEMENTSIN PATIENTS WITH NEUROTIC DISORDERS
Baburin I.N., Dagaev S.G., Dubinina E.E., Karvasarskiy B.D., Ksiupov T.B., Kubarskaya L.G., Poltorak S.V., Sokolyan N.A.
Abstract
43 patients with neurotic disorders (group 1) ,13 patients with cerebral residual organic neurosis-like disorders (group 2) and 13 healthy people (control group) were studied during their in-patient treatment in the Unit of neuroses and psychotherapy of the St. Petersburg V.M. Bekhterev Psychoneurological Research Institute in 2007-2010 year period. All the subjects of the study were in the age from 18 to 61 year. The patients (groups 1 and 2) filled in the SCL-90 questionnaire of psychopathological symptoms.All groups of the studied passed biochemical blood tests, tests indicating thelevel of oxidative stress and trace elements structure. All these characteristics were subject to correlation analysis. Interrelations of psychopathological symptoms indicated by SCL-90 and indicators of oxidative stress were revealed. These finding may help in neurotic disorders’ pathogenesis better understanding.
Neurology Bulletin. 2013;XLV(1):11-15
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INFLUENCE OF POST-STROKE MOTOR DISORDERS ON SELF-SUSTAINABILITY AND QUALITY OF LIFE
Kotsubinskaya J.V., Zakharov D.V., Mikhailov V.A.
Abstract
Successful rehabilitation of post-stroke patients is the result of the biological, psychological and social factors. There were used in this study some tests, such as test “level of rehabilitation” for assessment of dependence on aid of the caregivers, Ashworth scale for assessing neurological deficit, test “PULSES” for assessing the functional status of the patient (the ability to move independently, precise movements in the hands, the ability to control excretory functions, the changes in the psycho-emotional sphere). There was also applied questionnaire to assess the quality of life WHO QL-100. There were revealed some factors (biological, psychological and social) associated with social adaptation.
Neurology Bulletin. 2013;XLV(1):16-21
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INTERRELATION BETWEEN ANTICIPATION AND RELIGIOUS ACTIVITY AT PERSONS WITH NEUROTICDISORDERS
Frolova A.V.
Abstract
The results of studies of the anticipation peculiarities depending on the level of religious activity in neurotic disorders are resented. It is found that religious activity in the group of subjects with neurotic disorders is different (has its own specificity). It is shown that the predictive activity in patients with neurotic disorders is connected with religious activity and has its own characteristics.
Neurology Bulletin. 2013;XLV(1):22-26
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MICRODIALYSIS STUDY OF HIPPOCAMPAL GLUTAMATE AND GABA PROFILE IN RATS AFTER IMMUNIZATION BY GLUTAMATE-BSA CONJUGATE
Umryukhin A.E., Chekmareva N.Y., Sotnikov S.V., Vetrile L.A., Zaharova I.A.
Abstract
By means of microdialysis we studied stress induced changes of hippocampal glutamate and GABA profiles in active and passive rats immunized by glutamate-BSA conjugate. Glutamate level after stress exposure at the end of monitored hour period was higher in active immunized rats in comparison to nonimmunized active rats. GABA level during stress exposure significantly increased in active nonimmunized rats. Immunization of activerats by glutamate conjugate was accompanied by an increase of GABA concentration after stress exposure without any changes of GABA during stress exposure. These data demonstrate new conceptions on cerebral neurochemical effects of immunization by glutamate-BSA conjugate.
Neurology Bulletin. 2013;XLV(1):27-33
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COGNITIVE FLEXIBILITY AND STYLE AT EARLY DEVELOPED ALCOHOLISM IN MEN
Kopytov A.V., Skugarevsky O.A., Obyedkov V.G.
Abstract
The role of cognitive style and flexibility in alcohol dependence formation was evaluated in 157 adolescents and young males with alcohol dependence (main group, MG), 187 responders of control group without any signs of alcohol consumption problem and the comparison group of 110 male alcoholics with statistically significant older age and longer period of dependence than in MG and typically representing population tendencies for alcohol dependant male patients. Wisconsin Card Sorting Test has been used as a valid diagnostic instrument. There had not been noticed coarse and vivid lesions of cognitive style and flexibility, but there were revealed statistically reliable changes, evidencing the deficit of problem-solving behavior in this group.
Neurology Bulletin. 2013;XLV(1):34-39
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ANALYSIS OF GENE POLYMORPHISM, DETERMINING CARRIAGE OF HYPERHOMOCYSTEINEMIA IN RECURRENT ISCHEMIC STROKE IN YOUNG AND MIDDLE-AGED PATIENTS
Skorokhodov A.P., Dutova T.I.
Abstract
The analysis of gene polymorphism determining carrier hyperhomocysteinemia at recurrent ischemic stroke in young and middle-aged has been performed. It was shown that the level of homocysteine in recurrent ischemic stroke is higher than in single, and the level of vitamin B12 at repeated strokes is lower than at the individual ones, and level of folic acid is decreased both at the repeated insults, and at individual. The risk of ischemic stroke increases not only in the case of a combination of several mutations in the patient, leading to hyperhomocysteinemia, but also in any other combination of factors - both genetic and exogenous. The leading role in the development of hyperhomocysteinemia at ischemic stroke in young and middle age has (GE10), gene of methionine synthase reductase MTRR.
Neurology Bulletin. 2013;XLV(1):40-44
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EVOLUTION OF SPONTANEITY IN CHILDHOOD
Peskova L.I., Belousova M.V., Gavrikova I.J., Merkulova V.A.
Abstract
The article reads up-to-date information on the development of spontaneous regulation of the psychic activities and behavior during childhood and the potential of group psychocorrection for children and their family members. The article contains the information on the goals of the implementation of the program of the development of spontaneous regulation of children as well as the approaches of psychocorrection. There were shown the results of short-time work of a psychologist. Children, participating in the group and their parents
Neurology Bulletin. 2013;XLV(1):45-48
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COMPARATIVE ANALYSIS OF ANTICIPATIONAL CONSISTENCY OF CHILDREN WITH GENERAL SPEECH UNDERDEVELOPMENT AND NORMATIVE SPEECH DEVELOPMENT
Akhmetzyanova A.I.
Abstract
It is revealed that the general underdevelopment of speech as one of the leading factors that mediate mental and personal development, child’s adaptation during the pre-school age, has a connection with the violation of anticipation parameters of mental activity.
Neurology Bulletin. 2013;XLV(1):49-53
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THE RELATIONSHIP BETWEEN PARENTAL EDUCATION AND MATERNAL ATTITUDE IN GIRL-ADOLESCENTS WITH BEHAVIORAL DISORDER AND DRUG ADDICTION
Grechanyi S.V.
Abstract
The relationship between types of parental education and maternal attitude were studied in 101 girl-adolescents aged 13-18 with behavioral disorder and different drug addiction: opioid addiction, inhalant addiction, alcohol dependence, combined addiction of stimulants and cannabinoids. Three disadaptation styles of parental education were detected: panderring-inconsequential, directing-inconsequential and constant- directing.
Neurology Bulletin. 2013;XLV(1):54-59
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ANTENATAL AND INTRANATAL PREDICTORS OF ATTENTION DEFICIT HYPERACTIVITY DISORDER IN CHILDREN
Morozova E.A., Mendelevich V.D., Madyakina A.A.
Abstract
There were presented the factors of prenatal development and neurological disorders in the early postnatal period and infancy, making possible to identify predictors of attention deficit hyperactivity disorder (ADHD) and provide its prevention. The results of the study of 110 children with ADHD, showing features of perinatally caused ADHD, particularly its early debut, and the presence of certain comorbid conditions are given. Described predictors of ADHD.
Neurology Bulletin. 2013;XLV(1):60-66
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DAILY ALCOHOL TOLERANCE IN PATIENTS WITH ALCOHOLISM AS A RISK FACTOR FOR ACUTE ALCOHOLIC PSYCHOSIS AND SEIZURES
Shuvalov S.A., Kibitov A.O.
Abstract
Assessment of the role of tolerance to alcohol as a risk factor for acute alcoholic psychosis and seizures has been performed. In order to obtain quantitative data on alcohol tolerance was calculated daily rate of real tolerance as a result of reduction of volume indicators of different strength drinks, consumed during the day, to 40 ° alcohols. The relation of the real daily tolerance to age, diagnosis and family load of patients with complications of alcohol withdrawal was revealed. These data allow us to consider the daily tolerance to alcohol as a risk factor for acute alcoholic outcomes and seizures in young people, particularly those with family history of alcoholism.
Neurology Bulletin. 2013;XLV(1):67-76
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LINICAL-PHARMACOLOGICAL BASIS OF CARBAMAZEPINE USAGEIN ALCOHOLISM COMPLEX THERAPY
Sofronov A.G., Egorov A.Y.
Abstract
Carbamazepine main clinical-pharmacological characteristics are reviewed from the point of view its use in the alcoholism complex therapy. Its efficacy and safety is the same as in barbiturates, benzodiazepines, chlormethiazole and tiapride. Carbamazepine should be the drug of choice in patients with the risk of withdrawal seizures. In the alcohol withdrawal syndrome the combination of carbamazepine and other drugs (tiapride orchlormethiazole, in particularly is indicated. Carbamazepine has some preference compared to barbiturates and benzodiazepines: lack of addictiveness, sedation and cataleptic effects, cognitive suppression, cross-tolerance. Because of immunomodulating, anti-tumor, analgesic, antidiuretic, hepatoprotective and neurotropic effects carbamazepine may be used in the complex treatment of somatically complicated alcoholic patients.
Neurology Bulletin. 2013;XLV(1):77-86
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GLIAL BARRIERS AT SPINAL CORD INJURY AS A TARGET OF GENE-CELL THERAPY
Chelyshev Y.A., Shaymardanova G.F., Muhamedshina Y.O., Nigmetzyanova M.V.
Abstract
The role of glial barriers arising at spinal cord injury was shown. Along with the well-known its negative role there was discussed the positive role of glial barrier and reactive astrocytes in maintaining the structural integrity of the brain tissue and the process of neuroregeneration. Cytokines of transforming growth factor family regulate the phenotype of astrocytes and control the production of inhibitors of axonal regeneration. The results of our studies of evaluating the efficacy of posttraumatic regeneration of rat spinal cord in the expression of pathological cavitation during transplantation in the damaged area of osmetic mucosa cells and mononuclear cells of human umbilical cord blood, as well as local delivery to the same area of therapeutic genes ofneurotrophic and angiogenic factors vegf and fgf2are presented.
Neurology Bulletin. 2013;XLV(1):87-93
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HYSTERICAL DEPRIVATIONAL MANIPULATIONS: MECHANISMS, PHENOMENOLOGY, CORRECTION
Shaidukova L.K.
Abstract
The author has described phenomenology of deprivational manipulative behavior in hysterical disorders of different genesis; detected mechanisms, and given theoretical explanation of their origin. There has been defined nutritional, sexual, communicative, family-role, social-role, vital manipulations as a pathological form of interpersonal adaptation and an additional marker of hysterical disorders. There have been suggested differentiated correction methods of various hysterical manipulations.
Neurology Bulletin. 2013;XLV(1):94-99
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CHARACTERISTICS OF EMOTIONAL ATTACHMENT TO THE PARENTS OF PRESCHOOL CHILDREN WITH ADEQUATE AND INADEQUATE AGE-SEX IDENTITY
Minullina A.F., Akramova I.A.
Abstract
The article is devoted to the study of emotional attachment to the parents of preschool children with adequate and inadequate age-sex identity. Characteristics of emotional attachment to the parents of preschool children (with adequate and inadequate age-sex identity) were established. Similar and distinctive characteristics of emotional attachment to the parents of preschool children with adequate and inadequate age-sex identity were revealed. The availability and specificity of the relationships between the characteristics of emotional attachment to the parents and the characteristics of age-sex identity of preschool children were defined.
Neurology Bulletin. 2013;XLV(1):100-104
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PROFESSOR ALEXANDER VASILJEVICH GUSTOV
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Abstract
Neurology Bulletin. 2013;XLV(1):105-106
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