Analysis of the range of soft dosage forms for oral administration containing substances of plant origin

The purpose of the study: to study the range of soft dosage forms for oral medications administration containing substances of plant origin. Material and methods. This study used methods of content analysis, data aggregation, and comparative analysis. Data from the State register of medicinal products (GRLS) and the Russian register of medicinal products (RLS) as of February 28, 2020 were used as information bases for the study. Statistical data processing was performed using MSExcel 2016. The results of a study of the current state of pharmaceutical science in the field of creating alternative tablets and capsules for oral dosage forms showed that gels are promising for the delivery of various groups of biologically active substances for the prevention and treatment of a wide range of nosological forms. According to the State Register of Medicinal Products on the territory of the Russian Federation, two foreign-made medicines are registered in the form of a soft dosage form for oral administration: paste and paste for the preparation of a suspension for oral administration. The main group of dietary supplements for food in this category is used as a source of vitamins, micro and macro elements, as well as drugs used in the complex treatment of diseases of the urinary system, nervous system, and cardiovascular system. As the active substance of such dietary supplements to food, a complex of plant extracts is mainly used. Structuring agents that ensure the stability of the dosage form, mainly of natural and semi-synthetic origin. The leading position among the manufacturing countries of dietary supplements and drugs is Russia. Conclusion. The above information indicates the need to expand the range and increase the number of domestic drugs in the form of gels for oral administration and the undoubted relevance of this area.

oral gel, nomenclature analysis, soft dosage forms, substances of plant origin