Content of macroelements in the hair of residents of West Kazakhstan


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Abstract

Aim. To study gender and age characteristics of the content of macronutrients Ca, K, Mg, Na, P in the hair of representatives of the population of Western Kazakhstan. Material and methods. A one-time cross-sectional study was carried out in the West Kazakhstan and Aktobe regions of the Republic of Kazakhstan. We examined 609 adult residents permanently residing in the studied region: 391 women (64.2%) and 218 men (34.8%) aged 18 to 60 years. Investigations of the macroelement composition of hair were carried out using inductively coupled plasma mass spectrometry. Results. The content of macronutrients Ca, K, Mg, Na, P in hair had gender differences with higher concentrations of P, K, Na in men, and Ca, Mg in women. In the hair of men and women, the concentrations of K and Na significantly changed with age. At the age of 50-54 and 55-60 years, the content of K in the hair of men was 211% and 185% higher, and the content of Na was 237% and 177% higher than in men aged 18-24 years. The content of K in the hair of women 55-60 years old was significantly higher than in the age categories 18-24; 30-34 and 35-39 years old by 242%, 76% and 105%, respectively. The Na content in the hair of women 55-60 years old was significantly higher than that of those aged 18-24; 25-29 years old; 30-34; 35-39 and 40-44 years by 158%, 141%, 139%, 85% and 104%, respectively. In multivariate linear regression analysis, age, sex, BMI predicted the content of Ca, Mg, K, Na. Conclusions. The content of macronutrients in the hair of the adult population of Western Kazakhstan has gender differences with higher concentrations of P, K, Na in men, and Ca, Mg in women. The content of K and Na in hair of men and women significantly increases with age. Changes in the content of K and Na in hair observed with age can be associated with the aging process and a decrease in the functional capabilities of the body. An increase in BMI leads to an increase in the level of Na and K and a decrease in the level of Ca and Mg in the hair.

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About the authors

G. A Batyrova

West Kazakhstan Marat Ospanov Medical University

Email: batyrovagulnara77@gmail.com
PhD, Head of the Department of Clinical Laboratory and Visual Diagnostics

A. Amanzholkyzy

West Kazakhstan Marat Ospanov Medical University

Email: a.ainur.82@mail.ru
PhD, Associate Professor of the Department of Normal Physiology

G. A Umarova

West Kazakhstan Marat Ospanov Medical University

Master of Medicine Sciences, Lecturer of the Department of Evidence-Based Medicine and Scientific Management

Zh. Sh Tlegenova

West Kazakhstan Marat Ospanov Medical University

PhD, Associate Professor of the Department of Internal Diseases No. 2

V. I Kononets

West Kazakhstan Marat Ospanov Medical University

Master of Medical Sciences, Lecturer of the Department of Natural Sciences

A. A Mamyrbayev

West Kazakhstan Marat Ospanov Medical University

Dr.Sc. (Med.), Professor of the Department of Hygienic Disciplines with Occupational Disease

G. M Zharmakhanova

West Kazakhstan Marat Ospanov Medical University

PhD, Head of the Department of Natural Sciences

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