Chemical constituents of Sphallerocarpus gracilis (Besser ex Trevir.) essential oils from Buryatian flora

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Relevance. Sphallerocarpus gracilis (Besser ex Trevir.) Koso-Pol. (Umbelliferae) is a biennial pubescent plant widely used in the practice of Oriental medicine. Research on S. gracilis is attracting increasing attentiom due to its potential biological zctivities: antioxidant, hepatoprotective effects, anticancer properties, essential oils exhibit significant antimicrobial properties.

Material and methods. Essential oils of the aerial part and roots of the Sphallerocarpus gracilis from Mukhorshibirsky district of the Republic of Buryatia, collected during the period of mass flowering (August, 2022), were studied. Essential oils from the herbs and roots were isolated by hydrodistillation method. The content of essential oils was found by volumetric method. The qualitative composition and quantitative content of essential oils components were determined by gas chromatography-mass spectrometry method.

Results. The qualitative composition and quantitative content of essential oils components of the aerial part and roots of Sphallerocarpus gracilis from Buryatian flora studied for the first time. The main components of the essential oils of the aerial part are geranyl tiglate (7.56%) and apiol (71.83%); the roots are γ-terpinene (45.17%), p-cymene (9.38%) and trans-asarone (13.29%).

Conclusion. It has been shown that the aerial part of S. gracilis is a rich source of apiol, while the roots – compounds of monoterpene nature.

Full Text

Restricted Access

About the authors

Zh. A. Tykheev

Baikal Institute of Nature Management Siberian branch of the Russian Academy of Sciences; V.R. Fillipov Buryat State Agricultural Academy

Author for correspondence.
Email: gagarin199313@gmail.com

Ph.D. (Pharm.), Head of Laboratory of Physiologically Active Substances and Phyto-engeneering; Senior Researcher, Laboratory of Medicinal Herbs

Russian Federation, Ulan-Ude, Buryatia; Ulan-Ude, Buryatia

N. P. Rabdanova

Baikal Institute of Nature Management Siberian branch of the Russian Academy of Sciences

Email: gagarin199313@gmail.com

Junior Researcher, Laboratory of Physiologically Active Substances and Phyto-engeneering

Russian Federation, Ulan-Ude, Buryatia

M. V. Kazakov

Baikal Institute of Nature Management Siberian branch of the Russian Academy of Sciences

Email: gagarin199313@gmail.com

Researcher, Laboratory of Physiologically Active Substances and Phyto-engeneering

Russian Federation, Ulan-Ude, Buryatia

S. V. Zhigzhitzhapova

Baikal Institute of Nature Management Siberian branch of the Russian Academy of Sciences

Email: gagarin199313@gmail.com

Ph.D. (Biol.), Senior Researcher, Laboratory of Chemistry of Natural Systems

Russian Federation, Ulan-Ude, Buryatia

E. P. Dylenova

V.R. Fillipov Buryat State Agricultural Academy; Baikal Institute of Nature Management Siberian branch of the Russian Academy of Sciences

Email: gagarin199313@gmail.com

Ph.D. (Pharm.), Head of Laboratory of Medicinal Herbs; Senior Researcher, Laboratory of Physiologically Active Substances and Phyto-engeneering

Russian Federation, Ulan-Ude, Buryatia; Ulan-Ude, Buryatia

V. V. Taraskin

Baikal Institute of Nature Management Siberian branch of the Russian Academy of Sciences; V.R. Fillipov Buryat State Agricultural Academy

Email: gagarin199313@gmail.com

Ph.D. (Pharm.), Head of Laboratory of Chemistry of Natural Systems; Senior Researcher, Laboratory of Medicinal Herbs

Russian Federation, Ulan-Ude, Buryatia; Ulan-Ude, Buryatia

References

  1. Pimenov M.G., Ostroumova T.A. Zontichnye (Umbelliferae) Rossii. M.: Tovarishhestvo nauchnyh izdanij KMK, 2012; 477 s.
  2. Gao C., Tian C., Lu Y., Xu J., Luo J., Guo X. Essential oil composition and antimicrobial activity of Sphallerocarpus gracilis seeds against selected food-related bacteria. Food Control. 2011; 22: 517–522.
  3. Aseeva T.A., Dashiev D.B., Dashiev A.D., Nikolaev S.M., Surkova N.A., Chehirova G.V., Jurina T.A. Tibetskaja medicina u burjat. Novosibirsk: Izdatel'stvo SO RAN, 2008; 324 s.
  4. Shatar S. Prjanye i vkusovye rastenija Mongolii. Ulaanbaatar, 1989
  5. Grubov V.I. Opredelitel' sosudistyh rastenij Mongolii. Leningrad: Nauka: Leningr. otd-nie, 1982; 442 s.
  6. Hajdav C., Altanchimjeg B., Varlamova T.S. Lekarstvennye rastenija v mongol'skoj medicine. Ulan-Bator: Gosizdatel'stvo, 1985; 390 s.
  7. Guo Z.B. Economic flora of Qinghai. Xining: Qinghai People’s Press, 1987; 417–418.
  8. Chen N.Y., Chen T., Shi J. Two new phenolic glucosides from Sphallerocarpus gracilis. Indian Journal of Chemistry Section B. 1997; 36: 107–109.
  9. Chen N.Y., Shi J., Chen T. Two quinones from the aerial parts of Sphallerocarpus gracilis. Chinese Chemical Letters. 1999; 10: 919–920.
  10. Shi J., Wang T., Chen N.Y. Structural analysis of new δ-lactone of linolenic acid from aerial parts of Sphallerocarpus Gracilis. Chinese Journal of Instrumental Analysis. 2001; 6: 32–35.
  11. Shi M.R., Pe D., Liu J.X., Di D.L. Chemical constituents from Sphallerocarpus gracilis. Biochemical Systematics and Ecology. 2012; 40: 1–3.
  12. Gao C., Lu Y., Tian C., Xu J., Guo X., Zhou R., Hao G. Main nutrients, phenolics, antioxidant activity, DNA damage protective effect and microstructure of Splallerocarpus gracilis roots at different harvest time. Food Chemistry. 2011; 127: 615–622.
  13. Konakchiev A., Shatar S., Altantsetseg, Todorova M., Radnaeva L.D., Zhigzhitzhapova S.V. The essential oil of Sphallerocarpus gracilis (Bess ex Trev) R-Pol from outer Mongolian Gobi. Journal of Essential Oil Bearing Plants. 2010; 13(5): 575–578.
  14. Altancjecjeg Sh., Shatar S., Amarzhargal A., Zhavzmaa N. Issledovanie himicheskogo sostava jefirnogo masla obmanchivoplodnika tonkogo (Sphallerocarpus gracilis K-Pol), proizrastajushhego v gornostepnoj zone Mongolii. Materialy VII-j mezhdunarodnoj nauchno-prakticheskoj konferencii, posvjashhennoj 70-letiju Gorno-Altajskogo gosudarstvennogo universiteta «Aktual'nye problemy sel'skogo hozjajstva gornyh territorij». Gorno-Altajsk, 06–08 ijunja 2019; 345–349
  15. Myagmar B.E., Aniya Y. Free radical scavenging action of medicinal herbs from Mongolia. Phytomedicine. 2000; 7(3): 221–229.
  16. Ma T., Sun X., Tian C., Luo J., Zheng C., Zhan J. Enrichment and purification of polyphenol extract from Sphallerocarpus gracilis stems and leaves and in vitro evaluation of DNA damage-protective activity and inhibitory effects of α-amylase and α-glucosidase. Molecules. 2015; 20: 21442–21457.
  17. Ma T., Sun X., Tian C., Zheng Y., Zheng C., Zhan J. Chemical composition and hepatoprotective effects of polyphenols extracted from the stems and leaves of Sphallerocarous gracilis. Journal of Functional Foods. 2015; 18: 673–683.
  18. Gao C., Tian C., Zhou R., Zhang R., Lu Y. Phenolic composition, DNA damage protective activity and hepato-protective effect of free phenolic extract from Sphallerocarpus gracilis seeds. International Immunopharmacology. 2014; 20: 238–247.
  19. Jia L., Nie X.J., Fang M. Effect of Sphallerocarpus gracilis polysaccharides on proliferation inhibition and apoptosis of sarcoma HepG2 and mouse lymphocyte leukemia P388. Food Sci. 2011; 32: 227–231.
  20. Ma T., Sun X., Tian C., Luo J., Zheng C., Zhan J. Polysaccharide extraction from Sphallerocarpus gracilis roots by response surface methodology. International Journal of Biological Macromolecules. 2016; 88: 162–170.
  21. Guo J., Liu Q., Wang C., Shi J., Zhang J. A polysaccharide isolated from Sphallerocarpus gracilis protects PC12 cells against hydrogen peroxide-induced injury. International Journal of Biological Macromolecules. 2019; 129: 1133–1139.
  22. Guo J., Wang J., Song S., Liu Q., Huang Y., Xu Y., Wei Y., Zhang J. Sphallerocarpus gracilis polysac-charide protects pancreatic β-cells via regulation of the bax/bcl-2, caspase-3, pdx-1 and insulin sig-naling pathways. International Journal of Biological Macromolecules. 2016; 93: 829–836.
  23. Atazhanova G.A. Terpenoidy jefirnyh masel rastenij. Rasprostranenie, himicheskaja modifikacija i biologicheskaja aktivnost'. M.: ICSPF, 2008; 288 s.
  24. Tykheev Zh.A., Zhigzhitzhapova S.V., Zhang F., Taraskin V.V., Anenkhonov O.A., Radnaeva L.D. Chen S. Constituents of Essential Oil and Lipid Fraction from the Aerial part of Bupleurum scorzonerifolium Willd. (Apiaceae) from Different Habitats; Molecules. 2018; 23: 1496.
  25. Tabassum A., Akram S., Mushtaq M. Zhapter 11 – Apiole. In A Centum of Valuable Plants Bioactives. Cambridge, MA, USA: Academic Press, 2021; 233–259.
  26. Semenov V.V., Tsyganov D.V., Semenova M.N., Chuprov-Netochin R.N., Raihstat M.M., Konyushkin L.D., Volynchuk P.B., Marusich E.I., Nazarenko V.V., Leonov S.V. Kiselyov A.S. Efficient synthesis of glaziovianin A isoflavone series from dill and parsley extracts and their in vitro/in vivo antimitotic activity. Journal of Natural Products. 2016; 79 (5): 1429–1438.
  27. Ӧztürk M. Anticholinesterase and antioxidant activities of Savoury (Satureja thymbra L.) with identified major terpenes of essential oil. Food Chemistry. 2012; 134: 48–54.
  28. Ramalho T.R., Filgueiras L.R., Oliveira M.T.P., Araujo Lima A.L., Bezerra-Santos C.R., Jancar S., Piuvezam M.R. Gamma-terpinene modulation of LPS-stimulated macrophages is dependent on the PGE2/IL-10 axis. Planta Medica. 2016; 82: 1341–1345.
  29. Oliveira Ramalho T.R.O., Oliveira M.T.P., Araujo Lima A.L., Bezerra-Santos C.R., Piuvezam M.R. Gamma-terpinene modulates acute inflammatory response in mice. Planta Medica. 2015; 81: 1248–1254.
  30. Nooshadokht M., Mirzaei M., Sharifi I., Sharifi F., Lashkari M., Amirheidari B. In silico and in vitro antileishmanial effects of gamma-terpinene: multifunctional modes of action. Chemico-Biological Interactions. 2022; 361: 109957.
  31. Bӧlow N., Kӧnig W.A. The role of germacrene D as a precursor in sesquiterpene biosynthesis: investigations of acid catalyzed, photochemically and thermally induced rearrangements. Phytochemistry. 2000; 55: 141–168.
  32. Plemenkov V.V. Himija izoprenoidov. Barnaul: Izd-vo Alt. un-ta, 2007; 322 s

Supplementary files

Supplementary Files
Action
1. JATS XML
Download
2. Figure. Diagram of the content of different groups of components of essential oils of S. gracilis of different parts and different places of growth

Download (274KB)
Indexing metadata

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies