Modern approaches to surgical treatment of pancreatic head pseudocysts
- 作者: Dao D.1, Sizonenko N.A.1, Goltsov V.R.1
-
隶属关系:
- Kirov Military Medical Academy
- 期: 卷 27, 编号 3 (2025)
- 页面: 421-428
- 栏目: Review
- ##submission.dateSubmitted##: 06.12.2024
- ##submission.dateAccepted##: 02.06.2025
- ##submission.datePublished##: 20.09.2025
- URL: https://journals.eco-vector.com/1682-7392/article/view/642632
- DOI: https://doi.org/10.17816/brmma642632
- EDN: https://elibrary.ru/BWKAFW
- ID: 642632
如何引用文章
详细
Various techniques for the treatment of patients with pancreatic head pseudocysts are available. This review analyzed scientific data on the feasibility and effectiveness of these methods, with the results as basis for selecting an individualized treatment approach. Data were searched in PubMed, Google Scholar, and eLIBRARY.RU. The sources used were published between 2014 and 2024, with some valuable studies dating back to 2008. In selecting scientific articles, their practical relevance to the topic was considered. Notably, modern clinical practice records an increasing incidence of pancreatic pseudocysts, with approximately 1.6–4.5 cases per 100,000 population annually. Concurrently, pancreatic head pseudocysts tend to have a more severe course, often leading to complications and complicating treatment. These pseudocysts are characterized by fibrous tissue formation in the pancreatic head and cephalic pancreatitis development. The treatment of patients with pancreatic head pseudocysts is extremely challenging. Currently, minimally invasive techniques are often employed in treating patients with pancreatic head pseudocysts. However, in cases of pancreatic head pseudocysts, these methods do not always yield favorable outcomes. Complications and recurrences frequently occur, requiring repeated interventions and even open surgery. The scientific sources lack a systematic presentation of treatment approaches for this patient category, and there is no consensus on the matter. A revision of methodological strategies for this issue, based on the principles of evidence-based medicine, is required to evaluate the effectiveness of various surgical treatments for patients with pancreatic head pseudocysts. Overall, the problem of surgical treatment for pancreatic head pseudocysts is clinically relevant and warrants further investigation.
全文:

作者简介
Duy Khanh Dao
Kirov Military Medical Academy
编辑信件的主要联系方式.
Email: vmeda-nio@mil.ru
ORCID iD: 0009-0005-1098-2102
Adjunct
俄罗斯联邦, 6Zh Akademika Lebedeva st., Saint Petersburg, 194044Nicolai Sizonenko
Kirov Military Medical Academy
Email: vmeda-nio@mil.ru
ORCID iD: 0000-0001-6455-0894
SPIN 代码: 1881-6237
MD, Cand. Sci. (Medicine)
俄罗斯联邦, Saint PetersburgValery Goltsov
Kirov Military Medical Academy
Email: vmeda-nio@mil.ru
ORCID iD: 0000-0002-1321-3510
SPIN 代码: 7458-9678
MD, Dr. Sci. (Medicine), Professor
俄罗斯联邦, Saint Petersburg参考
- Han C, Lv YW, Hu LH. Management of chronic pancreatitis: recent advances and future prospects. Ther Adv Gastroenterol. 2024;17:17562848241234480. doi: 10.1177/17562848241234480 EDN: FHLGPY
- Horiuchi A, Akehi S, Abe Y, et al. Mucinous cystadenoma of the pancreas associated with pancreatic pseudocyst. J Surg Case Rep. 2023;2023(2):rjad026. doi: 10.1093/jscr/rjad026 EDN: BFIBUF
- Nakatake R, Kitade H, Ishizaki M, et al. Giant hemorrhagic pancreatic pseudocyst with suspected cystic pancreatic tumor: a case report. J Surg Case Rep. 2024;2024(6):rjae393. doi: 10.1093/jscr/rjae393 EDN: OXHIQQ
- Romashchenko PN, Revin GO, Maistrenko NA. Successful treatment of large bilocular pancreatic pseudocysts using minimally invasive technologies. Grekov's Bulletin of Surgery. 2021;180(5):101–106. doi: 10.24884/0042-4625-2021-180-5-101-106 EDN: TIHWNQ
- Tan JH, Chin W, Shaikh AL, et al. Pancreatic pseudocyst: Dilemma of its recent management (Review). Exp Ther Med. 2021;21(2):159. doi: 10.3892/etm.2020.9590 EDN: MGVAXY
- Suleman M, Tadayo J, Tendwa I, et al. Pancreatic pseudocyst as a cause for gastric outlet obstruction. Clin Case Rep. 2023;11(3):e7122. doi: 10.1002/ccr3.7122 EDN: DBXGIO
- Shimizu K, Ito T, Irisawa A, et al. Evidence-based clinical practice guidelines for chronic pancreatitis 2021. J Gastroenterol. 2022;57(10):709–724. doi: 10.1007/s00535-022-01911-6 EDN: HAKFEJ
- Afilal I, Abbou W, Oukrid K, et al. Acute pancreatitis revealing an isolated hydatid pancreatic cyst simulating a pseudocyst: A case report. Radiol Case Rep. 2023;18(5):1868–1871. doi: 10.1016/j.radcr.2023.01.064 EDN: ZOGHQJ
- Szakó L, Gede N, Váradi A, et al. Early occurrence of pseudocysts in acute pancreatitis — A multicenter international cohort analysis of 2275 cases. Pancreatology. 2021;21(6):1161–1172. doi: 10.1016/j.pan.2021.05.007 EDN: LTABXR
- Durleshter VM, Genrikh SR, Makarenko AV, et al. Current treatment of pancreatic pseudocysts: a systematic review. Kuban Scientific Medical Bulletin. 2021;28(4):85–99. doi: 10.25207/1608-6228-2021-28-4-85-99 EDN: SRSSLO
- Zerem E, Kurtcehajic A, Kunosić S, et al. Current trends in acute pancreatitis: Diagnostic and therapeutic challenges. World J Gastroenterol. 2023;29(18):2747–2763. doi: 10.3748/wjg.v29.i18.2747 EDN: PVVVCP
- Groskreutz D, Ahmad Y, Vargas J, et al. Interventional management and diagnostic follow-up of a large pancreatic pseudocyst: A case report. Radiol Case Rep. 2023;18(1):60–63. doi: 10.1016/j.radcr.2022.09.100 EDN: HVZYXV
- Beger HG, Matsuno S, Cameron JL. Diseases of the pancreas: current surgical therapy. Berlin: Springer; 2008. 949 p. doi: 10.1007/978-3-540-28656-1
- Chari ST. Defining chronic pancreatitis. Pancreatology. 2016;16(5):694–695. doi: 10.1016/j.pan.2016.08.008
- Ramsey ML, Conwell DL, Hart PA. Complications of chronic pancreatitis. Dig Dis Sci. 2017;62(7):1745–1750. doi: 10.1007/s10620-017-4518-x EDN: MPKNZR
- Okasha HH, Awad A, El-Meligui A, et al. Cystic pancreatic lesions, the endless dilemma. World J Gastroenterol. 2021;27(21):2664–2680. doi: 10.3748/wjg.v27.i21.2664 EDN: CFNULR
- Nag DS, Swain BP, Anand R, et al. Pain management in chronic pancreatitis. World J Clin Cases. 2024;12(12):2016–2022. doi: 10.12998/wjcc.v12.i12.2016 EDN: WJWZCU
- Savin DV, Demin DB, Zheleznov LM. New method for surgical treatment of pancreatic head cysts. Annals of HPB Surgery. 2024;29(2):99–104. doi: 10.16931/1995-5464.2024-2-99-104 EDN: NGNHXC
- Gupta A, Chennatt JJ, Mandal C, et al. Approach to cystic lesions of the pancreas: Review of literature. Cureus. 2023;15(3):e36827. doi: 10.7759/cureus.36827 EDN: PFMNGO
- Zouridis S, Liu J, Wadhwa N, et al. Poor adherence to most recent guidelines on pancreatic cysts management: An ongoing problem. Pancreas. 2024;53(2):e221–e222. doi: 10.1097/MPA.0000000000002276 EDN: XZHUGQ
- Rogowska J, Semeradt J, Durko Ł, et al. Diagnostics and management of pancreatic cystic lesions: New techniques and guidelines. J Clin Med. 2024;13(16):4644. doi: 10.3390/jcm13164644 EDN: ZULCTS
- Quinn PL, Bansal S, Gallagher A, et al. Endoscopic versus laparoscopic drainage of pancreatic pseudocysts: A cost-effectiveness analysis. J Gastrointest Surg. 2022;26(8):1679–1685. doi: 10.1007/s11605-022-05346-5 EDN: OGWORC
- European Study Group on Cystic Tumours of the Pancreas. European evidence-based guidelines on pancreatic cystic neoplasms. Gut. 2018;67(5):789–804. doi: 10.1136/gutjnl-2018-316027
- Brown NG, Sethi A. Endoscopic drainage of pancreatic fluid collections. Gastrointest Endosc Clin N Am. 2024;34(3):553–575. doi: 10.1016/j.giec.2024.02.008 EDN: WKFAWN
- Elfert K, Chamay S, Santos LD, et al. Increasing trend of endoscopic drainage utilization for the management of pancreatic pseudocyst: Insights from a nationwide database. Clin Endosc. 2024;57(1):105–111. doi: 10.5946/ce.2023.054 EDN: LSZFAC
- Ivanusa SYa, Lazutkin MV, Shershen DP, et al. Differentiated approach to transmural endoscopic drainage in patients with pancreatic fluid formations. Moscow Surgical Journal. 2022;(4):9–19. doi: 10.17238/2072-3180-2022-4-9-19 EDN: CAHUAO
- Saul A, Ramirez Luna MA, Chan C, et al. EUS-guided drainage of pancreatic pseudocysts offers similar success and complications compared to surgical treatment but with a lower cost. Surg Endosc. 2016;30(4):1459–1465. doi: 10.1007/s00464-015-4351-2 EDN: WAUMXB
- Kluszczyk P, Jabłońska B, Serafin M, et al. What we know so far about ECG for pancreatic pseudocysts. Life (Basel). 2024;14(11):1419. doi: 10.3390/life14111419 EDN: BENCQA
- Bykova YuF, Solov'ev MM, Merzlikin NV, et al. Surgical treatment of pancreatic pseudocysts. Annals of HPB Surgery. 2017;21(4):100–107. doi: 10.16931/1995-5464.20164100-107
- Au KP, Chok KSH. Surgical cystogastrostomy: Is it still worthwhile? World J Gastroenterol. 2024;30(17):2298–2301. doi: 10.3748/wjg.v30.i17.2298 EDN: KCHVTX
- Koo JG, Liau MYQ, Kryvoruchko IA, et al. Pancreatic pseudocyst: The past, the present, and the future. World J Gastrointest Surg. 2024;16(7):1986–2002. doi: 10.4240/wjgs.v16.i7.1986 EDN: CLPWJE
- Pan G, Wan MH, Xie KL, et al. Classification and management of pancreatic pseudocysts. Medicine (Baltimore). 2015;94(24):e960. doi: 10.1097/MD.0000000000000960
- Ray S, Basu C, Dhali A, et al. Frey procedure for chronic pancreatitis: A narrative review. Ann Med Surg (Lond). 2022;80:104229. doi: 10.1016/j.amsu.2022.104229 EDN: EDTGTY
- Pryadko AS. Optimized approaches in surgical treatment of chronic pancreatitis patients [dissertation abstract]. Saint Petersburg; 2021. 46 p. Available from: https://www.dissercat.com/content/optimizirovannye-podkhody-v-khirurgicheskom-lechenii-bolnykh-khronicheskim-pankreatitom (In Russ.)
- Planz V, Galgano SJ. Percutaneous biopsy and drainage of the pancreas. Abdom Radiol (NY). 2022;47(8):2584–2603. doi: 10.1007/s00261-021-03244-z EDN: MGOGDT
- Teoh AY, Dhir V, Jin ZD, et al. Systematic review comparing endoscopic, percutaneous and surgical pancreatic pseudocyst drainage. World J Gastrointest Endosc. 2016;8(6):310–318. doi: 10.4253/wjge.v8.i6.310
- Faur M, Moisin A, Sabau AD, et al. The surgical management of pancreatic pseudocysts-outcomes on a group of seven patients. J Mind Med Sci. 2022;9(1):168–174. doi: 10.22543/7674.91.P168174 EDN: ELFBGS
- Ghorbani P, Dankha R, Brisson R, et al. Surgical outcomes and trends for chronic pancreatitis: An observational cohort study from a high-volume centre. J Clin Med. 2022;11(8):2105. doi: 10.3390/jcm11082105 EDN: IRWXAR
- Issa Y, Kempeneers MA, Bruno MJ, et al. Effect of early surgery vs endoscopy-first approach on pain in patients with chronic pancreatitis: The ESCAPE randomized clinical trial. JAMA. 2020;323(3):237–247. doi: 10.1001/jama.2019.20967 EDN: TOCFCY
- Starkov YuG, Zamolodchikov RD, Dzhantukhanova SV, et al. The results of endosonography-assisted internal drainage of pancreatic pseudocyst. Ann HPB Surg. 2019;24(1):43–52. doi: 10.16931/1995-5464.2019143-52 EDN: ZCKVVJ
- Varadarajulu S, Bang JY, Sutton BS, et al. Equal efficacy of endoscopic and surgical cystogastrostomy for pancreatic pseudocyst drainage in a randomized trial. Gastroenterology. 2013;145(3):583–590. doi: 10.1053/j.gastro.2013.05.046
- Tian Y, Yin C, Ma Y, et al. Lumen-apposing metal stents versus traditional self-expanding metal stents for endoscopic ultrasound-guided drainage of pancreatic fluid collections: A systematic review and meta-analysis. Surg Endosc. 2024;38(2):586–596. doi: 10.1007/s00464-023-10636-3 EDN: ZEDRRI
- Zhou X, Lin H, Su X, et al. Metal versus plastic stents for pancreatic fluid collection drainage: A systematic review and meta-analysis. J Clin Gastroenterol. 2021;55(8):652–660. doi: 10.1097/MCG.0000000000001539 EDN: PBMRVF
- Gambitta P, Maffioli A, Spiropoulos J, et al. Endoscopic ultrasound-guided drainage of pancreatic fluid collections: The impact of evolving experience and new technologies in diagnosis and treatment over the last two decades. Hepatobiliary Pancreat Dis Int. 2020;19(1):68–73. doi: 10.1016/j.hbpd.2019.09.008 EDN: BEYDNN
- Dorrell R, Pawa S, Pawa R. Endoscopic management of pancreatic fluid collections. J Clin Med. 2021;10(2):284. doi: 10.3390/jcm10020284 EDN: VPBWSL
- Guzmán-Calderón E, Chacaltana A, Díaz R, et al. Head-to-head comparison between endoscopic ultrasound guided lumen apposing metal stent and plastic stents for the treatment of pancreatic fluid collections: A systematic review and meta-analysis. J Hepatobiliary Pancreat Sci. 2022;29(2):198–211. doi: 10.1002/jhbp.1008 EDN: BDJHXC
- Lera Dos Santos ME, Proença IM, de Moura DTH, et al. Self-expandable metal stent (SEMS) versus lumen-apposing metal stent (LAMS) for drainage of pancreatic fluid collections: A randomized clinical trial. Cureus. 2023;15(4):e37731. doi: 10.7759/cureus.37731 EDN: QZPRJB
- Ke N, Jia D, Huang W, et al. Earlier surgery improves outcomes from painful chronic pancreatitis. Medicine (Baltimore). 2018;97(19):e0651. doi: 10.1097/MD.0000000000010651
- Li SZ, Zhen TT, Wu Y, et al. Quality of life after pancreatic surgery. World J Gastroenterol. 2024;30(8):943–955. doi: 10.3748/wjg.v30.i8.943 EDN: RYIEJU
- Bachmann K, Tomkoetter L, Erbes J, et al. Beger and Frey procedures for treatment of chronic pancreatitis: Comparison of outcomes at 16-year follow-up. J Am Coll Surg. 2014;219(2):208–216. doi: 10.1016/j.jamcollsurg.2014.03.040
- Zorzi A, Campagnola P, Amodio A, et al. An update on improving long-term outcomes for patients with chronic pancreatitis post-surgery. Expert Rev Gastroenterol Hepatol. 2024;18(1-3):25–36. doi: 10.1080/17474124.2024.2321947 EDN: IPRFPU
- Cahen DL, Gouma DJ, Laramée P, et al. Long-term outcomes of endoscopic vs surgical drainage of the pancreatic duct in patients with chronic pancreatitis. Gastroenterology. 2011;141(5):1690–1695. doi: 10.1053/j.gastro.2011.07.049
- Kalayarasan R, Shukla A. Changing trends in the minimally invasive surgery for chronic pancreatitis. World J Gastroenterol. 2023;29(14):2101–2113. doi: 10.3748/wjg.v29.i14.2101 EDN: FWLVEK
- Zerem E, Imamovic G, Omerovic S, et al. Percutaneous treatment for symptomatic pancreatic pseudocysts: Long-term results in a single center. Eur J Intern Med. 2010;21(5):393–397. doi: 10.1016/j.ejim.2010.06.015
- Farias GFA, Bernardo WM, de Moura DTH, et al. Endoscopic versus surgical treatment for pancreatic pseudocysts: Systematic review and meta-analysis. Medicine (Baltimore). 2019;98(8):e14255. doi: 10.1097/MD.0000000000014255
- Dindo D, Demartines N, Clavien PA. Classification of surgical complications: A new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240(2):205–213. doi: 10.1097/ данного списка убрать только нумерацию 01.sla.0000133083.54934.ae
补充文件
