Cardiovascular complications in patients after coronavirus DISEASE-2019
- Authors: Mirzoev N.T.1, Kutelev G.G.1, Pugachev M.I.1, Kireeva E.B.1
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Affiliations:
- Military medical academy of S.M. Kirov
- Issue: Vol 24, No 1 (2022)
- Pages: 199-208
- Section: Review
- URL: https://journals.eco-vector.com/1682-7392/article/view/90733
- DOI: https://doi.org/10.17816/brmma90733
- ID: 90733
Cite item
Abstract
The data of the modern literature describing the long-term consequences of infection of the body with SARS-CoV-2 on the cardiovascular system in the framework of postcovid syndrome are analyzed. To date, postcovid syndrome refers to a condition in which symptoms continue to persist for more than 12 weeks from the moment of diagnosis of COVID-19. Various complaints of patients after undergoing a new coronavirus infection are described, the distinguishing feature of which is their versatility, where cardiovascular manifestations are assigned one of the leading roles. Postural orthostatic tachycardia syndrome, cardiac arrhythmia and conduction disorders are considered. The role of SARS-CoV-2 in the formation of de novo and decompensation of pre-existing cardiovascular diseases has been demonstrated. The possibility of developing heart failure in patients with COVID-19 as an outcome of inflammation of the heart muscle is shown. Particular attention is paid to the analysis of the incidence of myocarditis after 3 months or more from the diagnosis of COVID-19, as well as thrombotic complications, in the genesis of which the main role belongs to the formation of endothelial dysfunction resulting from the interaction of SARS-CoV-2 with vascular endothelial cells. The autoimmune component of the pathogenesis of damage to the cardiovascular system as a result of the formation of endothelial dysfunction in COVID-19 is also considered. The authors present a laboratory-instrumental algorithm for determining cardiovascular complications in people who have undergone COVID-19, including the determination of the N-terminal fragment of the brain natriuretic peptide B-type prohormone, the level of anticardial antibodies, electrocardiography, echocardiography, as well as magnetic resonance imaging of the heart with contrast.
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About the authors
Nikita T. Mirzoev
Military medical academy of S.M. Kirov
Email: mirsoev@mail.ru
ORCID iD: 0000-0002-9232-6459
SPIN-code: 9826-5624
resident
Russian Federation, Saint PetersburgGennady G. Kutelev
Military medical academy of S.M. Kirov
Email: gena08@yandex.ru
ORCID iD: 0000-0002-6489-9938
SPIN-code: 5139-8511
candidate of medical sciencesRussian Federation, Saint Petersburg
Maxim I. Pugachev
Military medical academy of S.M. Kirov
Author for correspondence.
Email: kenig.max@mail.ru
ORCID iD: 0000-0001-5523-8233
SPIN-code: 1549-6552
candidate of medical sciences
Russian Federation, Saint PetersburgElena B. Kireeva
Military medical academy of S.M. Kirov
Email: kirr72@mail.ru
SPIN-code: 8954-1927
candidate of medical sciences
Russian Federation, Saint PetersburgReferences
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