Prevention of hemorrhagic complications during hybrid interference in the sleepy and coronary arteries under conditions of hypo-agregation and hypocaagulation

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Hemorrhagic complications in patients after hybrid interventions including percutaneous coronary intervention and carotid endarterectomy are analyzed. Demonstrate a new method of hemostasis and wound drainage after carotid endarterectomy. It was found that at the preoperative stage, the coagulogram parameters were within the normal range, but the aggregatogram showed hypoagregation for two of the four inducers in all 84 operated patients. After the completion of the second stage of revascularization, the absolute partial thrombosed time in all patients was five to six times higher than normal in the coagulogram parameters. According to the aggregatogram, there was a total hypo-aggregation. All acute hematomas after carotid endarterectomy requiring revision were formed in patients with the traditional method of hemostasis and wound drainage after carotid endarterectomy (p = 0.038), which was associated with more frequent damage to the cranial nerves (p = 0.0002). Thus, the combined endpoint, including the indicator of cranial nerve damage + acute hematoma in patients with the traditional method of hemostasis and wound drainage after carotid endarterectomy, significantly exceeded it in patients who used a new tactic (local hemostatics with minimal electrocoagulation and installation of two drains in the paravasal and clitoral space) (p < 0.0001). There were no cases of wound complications in the area of carotid endarterectomy. Thus, the new technique of hemostasis and wound drainage after carotid endarterectomy against the background of hypocoagulation and hypoagregation has shown its effectiveness and preventive role in the prevention of hemorrhagic complications, damage to the cranial nerves.

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作者简介

Anton Kazantsev

Alexander Hospital

编辑信件的主要联系方式.
Email: dr.antonio.kazantsev@mail.ru
ORCID iD: 0000-0002-1115-609X

cardiovascular surgeon

俄罗斯联邦, Saint Petersburg

Konstantin Chernykh

Alexander Hospital

Email: cvs.doc@yandex.ru
ORCID iD: 0000-0002-5089-5549

cardiovascular surgeon

俄罗斯联邦, Saint Petersburg

Goderzi Baghdavadze

Alexander Hospital

Email: gud_777@bk.ru
ORCID iD: 0000-0001-5970-6209

resident

俄罗斯联邦, Saint Petersburg

参考

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  3. Barbarash LS, Tarasov RS, Kazantsev AN, et al. Factors of poor prognosis of various surgical strategies for the treatment of patients with combined lesions of the coronary and brachycephalic arteries in the long-term postoperative period. Cardiology and Cardiovascular Surgery. 2017;10(2):22–39. (In Russ.). doi: 10.17116/kardio201710222-39
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  10. Kazantsev AN, Tarasov RS, Burkov NN, et al. Hospital results of percutaneous coronary intervention and carotid endarterectomy in hybrid and staged modes. Angiology and Vascular Surgery. 2019;25(1):101–107. (In Russ.). doi: 10.33529/angio2019114
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