No 18 (2014)

The drug Zeel T is widely used for the treatment of degenerative diseases of the musculoskeletal system. It has significant anti-inflammatory and analgesic effects that allows to recommend this drug as a valuable alternative to NSAIDs. However, the major importance of Zeel Tincludes additional chondroprotective and chondrostimulating action.

Phenazepam is effective in different states and is used in almost every field of medicine, as a highly effective, fast and safe way for the solution of a great number of tactical challenges that clinicians face in their practice. At the same time, application of phenazepam (and all benzodiazepines) is not recommended for the long-term therapy. The course of treatment should not exceed 1 month. It is obvious that the combination of a broad therapeutic profile of the drug, the efficacy and safety of its action still determine unmet need for phenazepam in the treatment of mental disorders with anxiety symptoms, psychosomatic disorders, and in some cases - physical illness as an adjuvant therapy.

The article presents the results of evaluation of antihypertensive and lipid-lowering effectiveness of combined antihypertensive therapy using angiotensin converting enzyme (ACE) inhibitor Fozinotek (fosinopril) in the starting dose of 10 mg/day, thiazide diuretic Retapres (indapamide) at the starting dose of 1.5 mg/day in combination with diet or with the addition of Simvor (simvastatin). It is shown that the combination therapy in patients with dyslipidemic hypertension using ACE inhibitor and a statin can significantly reduce the risk of cardiovascular events. Despite equal antihypertensive effect, combination of fosinopril and simvastatin was significantly more effective compared to therapy with fosinopril in reducing the risk of major cardiovascular complications. Enhancement of clinical effect with the combination of ACE inhibitors and statins can be explained, most likely, not by the synergism of antihypertensive or lipid-lowering effects, but the synergistic angioprotective action.

Coronary artery disease (CAD) - a chronic pathology that has a multifactorial etiology. Clinical and epidemiological studies have shown that hypomagnesaemia increases the risks for CAD, unstable angina, and cardiovascular mortality due to myocardial dysfunction, mitochondrial failure and comorbid diseases. The article considers the evidence-based data on the oral use of magnesium-containing preparations based on organic salts in the prevention and treatment of coronary artery disease.

In the clinical practice, search and implementation of methods and ways of prevention and treatment of acute respiratory viral infections continue to be a priority. Accordingly, the homeopathic drugs that have little or no contraindications and age restrictions, have no side effects and can be used in combination with other drugs, including during therapy of concomitant pathology, are of particular interest. Oscillococcinum is one of such drugs used in the treatment of acute respiratory infections.

Amoxicillin is oral antibiotic, representative of the group of aminopenicillins. Amoxicillin has wide spectrum of antimicrobial activity, good pharmacokinetic characteristics and safety profile; antibiotic resistance of the main pathogens of bacterial infections of ENT organs, as well as long-term experience of use of amoxicillin by physicians, pulmonologists, otolaryngologists, pediatricians, and the availability of suitable dosage forms of the drug, including for children, define the appropriateness of its use as a drug of choice in the treatment of non-severe community-acquired respiratory tract infections.

The article describes the types of neuropathic pain. Spontaneous and evoked positive sensory symptoms associated with neuropathic pain discriminated. The stages necessary for the diagnosis of neuropathic syndrome are presented. The principles of treatment of neuropathic pain according to international recommendations are considered. It is emphasized that selection of treatment should be determined by the leading pathophysiological processes specific to pain. It is noted that bee venom-containing drugs suppress the occurrence of mechanical and cold allodynia and are effective for all types of pain involving inflammation.