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No 4 (2016)
- Year: 2016
- Articles: 11
- URL: https://journals.eco-vector.com/2073-4034/issue/view/6981
Articles
SUPPORTING TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Abstract
Tiotropium is the drug of first-line supporting treatment of chronic obstructive pulmonary disease (COPD), the efficacy and safety of which is supported by higher level evidence and broad experience of the use in medical practice. Many pharmacoeconomic studies have shown that the clinical benefits of tiotropium compared with placebo and active comparators lead to its economic advantages, primarily by reducing the cost of hospitalization, and allow to consider the tiotropium as a drug of choice for the supporting treatment of COPD.
Pharmateca. 2016;(4):8-13
8-13
COMPOSITION OF NATURAL ESSENTIAL OILS: PLACE IN THE PREVENTION AND COMPREHENSIVE TREATMENT OF ACUTE RESPIRATORY INFECTIONS IN CHILDREN
Abstract
The article provides a brief review of the literature on the use of plant essential oils in clinical practice. The therapeutic effects and mechanisms of influence on the human body of essential oils of various plants are discussed. The data of the efficacy and safety of essential oils in the treatment of acute infectious respiratory diseases in children by the example of domestic preparation, containing composition of natural essential oils - «Oil Dishi» - are presented.
Pharmateca. 2016;(4):14-20
14-20
INFLUENZA AND SEVERE PNEUMONIA: KEY ISSUES OF DIAGNOSIS, PHARMACOTHERAPY, AND PREVENTION
Abstract
The article discusses the modern approaches to the treatment of influenza and pneumonia - one of the most dangerous complications of influenza infection. The etiopathogenesis and clinical manifestations of influenza and pneumonia are described; the order of diagnosis and care for patients with these diseases, as well as practical advice on the management of patients with influenza and pneumonia are presented.
Pharmateca. 2016;(4):21-26
21-26
DIAGNOSIS OF BRONCHIAL ASTHMA IN CHILDREN
Abstract
The article deals with the issues of diagnosis of bronchial asthma (BA) in children. Clinical, functional and allergological criteria for diagnosis of BA in childhood are presented. The clinical features of BA in children of different age groups are described. Current potentials for verification of diagnosis of BA in children using respiratory function tests are discussed.
Pharmateca. 2016;(4):27-33
27-33
LONG-ACTING ANTICHOLINERGICS IN THE TREATMENT OF BRONCHIAL ASTHMA
Abstract
The article provides an overview of the studies on the role of tiotropium bromide in the treatment of bronchial asthma (BA); the prerequisites for the application of long-acting anticholinergics in bronchial asthma are disclosed, and pharmacological properties of tiotropium bromide are discussed. Currently, it is proved that the addition of tiotropium to standard therapy of patients with severe uncontrolled BA results in improved lung function and reduced risk of relapses. Ongoing studies of the drug can extend the range of its indications in bronchial asthma.
Pharmateca. 2016;(4):34-40
34-40
MODERN APPROACH TO SOLVE PROBLEMS WITH COUGH IN ACUTE RESPIRATORY INFECTIONS IN ADULTS
Abstract
The article presents a review of studies on the effectiveness and safety of Rengalin - domestic innovative drug for the combined treatment of any kind of cough in acute respiratory infections. The results of studies showed that the combined composition of Rengalin provides its effective and safe complex antitussive, anti-inflammatory and bronchodilator actions, prevents polypharmacy, minimizes drug load on the body, as well as makes cough treatment convenient for the physician and the patient, and reduces the cost of treatment.
Pharmateca. 2016;(4):41-47
41-47
48-51
OTITIS EXTERNA IN GENERAL PRACTICE
Abstract
The article discusses the etiology, pathogenesis and treatment of otitis externa in general practice. It was noted that in spite of the well state of knowledge, to date there is no universal classification of otitis externa, which would be unanimously adopted by all the experts. Given that the medical tactics in otitis externa depends on its nature, in some cases, the combined drugs appear to be most optimal for the treatment. The data of author’s own clinical experience of use of Triderm in patients with external otitis against the background of hearing aid are presented. These results allow to recommend the drug as a first choice for otitis externa caused by atopic dermatitis, bacterial and mycotic eczema.
Pharmateca. 2016;(4):52-55
52-55
DIAGNOSIS AND TREATMENT OF ASPIRATION SYNDROME IN INFANTS
Abstract
Objective: to study the frequency of aspiration processes in children admitted with respiratory complaints; to evaluate the effectiveness of different treatments of microaspiration syndrome. Methods: for detecting the frequency of aspiration syndrome in infants and young children with acute lower respiratory tract lesions without neurological disorders, monitoring of 162 children in the period 2013-2015 was conducted. The comparison group consisted of 24 children with aspiration on the background of an organic lesion of the central nervous system. Results: Of 162 children surveyed, signs of aspiration were revealed in 27 cases, accounting for 16.7%. Aspiration syndrome incidence was highest in the first six months of life; of the 67 children admitted to hospital with acute lower respiratory tract lesions without concomitant neurologic disease before the age of 6 months, aspiration was detected in 17 cases (25%). Gastroesophageal reflux (GER) occurred in 4 children in the first six months of life, which was not different from the frequency of GER in healthy children. Of 88 children in the latter six months, only 3 children had signs of microaspiration (3.5%). Of the 47 neurologically healthy children, recurrent symptoms of broncho-pulmonary diseases were observed in 20 children. Conclusion: These data show that the food microaspiration is sufficiently frequent cause of respiratory syndrome, especially among infants. Respiratory syndrome in children with the food microaspiration syndrome is characterized by repeated episodes of cough, obstruction with a trend towards prolonged duration due to the continuing aspiration.
Pharmateca. 2016;(4):56-61
56-61
MODERN POTENTIALS FOR THE TREATMENT OF POSTINFECTIOUS COUGH
Abstract
The article presents the results of an analysis of the literature on the issue of post-infectious cough. The urgency of the matter is due to the high prevalence of patients with this pathology, both among adults and children. There is a lack of clarity of etiopathogenesis and lack of clear treatment algorithm. Among the medication used for the treatment of post-infectious cough, mucoactive drugs have good efficacy. In particular, drug Eucabal has complex mucolytic, expectorant and anti-inflammatory action. The studies have shown efficacy of Eucabal in patients with acute and subacute cough after acute respiratory viral infections, as well as good tolerance among the different age categories of patients, including infants.
Pharmateca. 2016;(4):62-65
62-65
POTENTIALS FOR THE USE OF AMBROXOL IN VARIOUS RESPIRATORY DISEASES
Abstract
This article is dedicated to the analysis of the results of clinical studies on the efficacy and safety of ambroxol hydrochloride. Classification and mechanism of action of mucolytics are considered in details. Current evidence on the effectiveness of ambroxol against bacterial films is analyzed that attaches special importance in the present conditions of antibiotic resistance. A comparative evaluation of pharmacokinetic and pharmacodynamic characteristics of the drug compared with bromhexine is performed. It is emphasized that ambroxol has higher bioavailability as compared with bromhexine, allowing to regard this drug as the most effective in this pharmacotherapeutic group.
Pharmateca. 2016;(4):66-71
66-71