Vol 3, No 1 (2015)

Feijoa leaves gathered from Feijoa sellowiana Berg. of Myrtaceae family on the Black Sea coast of the Caucasus were the object of this research. Establishment of morphological and anatomical features for diagnosis of feijoa leaves was the purpose of this work. Using macro- and microscopic analysis methods we have determined external and microdiagnostic features which can be used for development of authenticity of the feijoa leaves active parts.

Eryngium planum L. is one of bi-perennial plants and hemicryptophyte. It is successfully introduced in cultivation in CMW conditions. The plant reaches 70 cm. One plant can contain up to 16 000 seeds. It is possible to obtain about 4.9 t/ha of air-dry weight, 4.2 t/ha of roots, and 3.59 hwt/ha of seeds from 1 ha.

The article reviews the use of maltodextrine as one of the active substances in external drug forms which are used in purulent and inflammatory processes treatment abroad. The article considers a manufacturing prospect of import-substituting preparations on the basis of domestic maltodextrin.

We have carried out preliminary analysis of foreseeable biological activity of some compounds derivants of 4-oxopyrimidine with a use of PASS program. We have established that they should have anti-inflammatory, benzothiazepine, analgesic, hypotensive, nootropic activity. Molecular docking method (Autodock 4.0) allowed modeling of interaction of 4-oxopyrimidine derivatives with GABA, dopamine and benzothiazepine receptors. On the basis of the data received we forecasted structures of N-aromatic derivatives of 4-oxopyrimidine. The derivatives of 4-oxopyrimidine we received with a reaction of cyclocondensation of N-acyl-β-ketamides with aromatic amines. We have synthesized five compounds. Using IR, UV and NMR spectrometry we have established its presumable structure as well as some physical and optical parameters. We have elaborated methods of quantitative spectrophotometric determination of two synthesized compounds and made its validation estimation.

There are results of experimental studies in the quality norms, stability study and establishment of shelf-life of cosmeceutical forms with CO 2 extract of Schizandra chinensis seeds using UV spectrophotometry and chromatographic analysis methods. The quality norms established may be recommended for normative documentation stipulation in future. The approximate shelf-life for the napkins under study was 24 months.

We have developed a methodology of quantitative determination of sesquiterpenic lactones (costunolide and dehydrocostuslactone) in leaves of Laurus nobilis using reversed phase HPLC. We have determined optimal conditions for the substances under study extraction from active parts. Using the developed methods we have established that costunolide and dehydrocostuslactone content in Laurus nobilis samples in terms of absolutely dry active parts is 0.99 and 0.26% correspondingly.

The article presents data about Fotosan device and its implementation in complex treatment of oral and labial muscosa diseases. The obtained results evidence that 84% of observed patients had significant reduction of pain, swellings and regeneration acceleration in 1.5 - 2 times.

The article shows the results of assortment analysis of drugs applied in rehabilitation treatment of neurology patients in departmental health centers injured in terrorist attacks.

We have studied and analyzed one of the items of HR policy - personnel education - in this article. During the sociological research we have estimated its influence on efficiency of pharmacy organization staff work. We have outlined and studied 4 basic directions in personnel education.