Pharmacy Formulas

A periodical scientific publication, the journal " Formulas of Pharmacy "(hereinafter-the publication), for publishing the main scientific results of dissertations for the degree of candidate of Sciences, for the degree of doctor of Sciences; presents high-quality, peer-reviewed research and interactive clinical content.

Our journal is focused on clinical pharmacologists, specialists of expert organizations, workers centers preclinical and clinical trials of medicinal products; employees of regulatory and Supervisory organizations and institutions in the field of pharmaceutical industry and Russian Ministry of health; researchers, medical and pharmaceutical workers of the organisations and institutions of the Ministry of health; experts of the scientific organizations of RAS and other researchers in the field of environmental security.

The topics of published materials are limited to two branches of science - medical and biological - and they correspond to groups of scientific specialties (03.02.00 General biology, 14.03.00 Biomedical sciences, 14.04.00 Pharmaceutical sciences) in accordance with the order of the Ministry of Education of the Russian Federation dated October 23, 2017 No. 1027 "On the approval of the nomenclature of scientific specialties for which science degrees are awarded" and by order of the Ministry of Education and Science of the Russian Federation of December 12, 2016 No. 1586 (revised March 27, 2018) "On the approval of the rules for forming the list of peer-reviewed scientific publications."

The publication complies with modern rules and requirements of domestic and foreign legislation for peer-reviewed scientific publications.

Journal strategy

When preparing each issue, members of the editorial Board intend to take into account modern requirements for the order of qualified review, information openness and bibliometric indicators in assessing the publication activity of authors, along with other factors of the journal.

To this end, the editorial team uses rigorous: editorial, expert, and statistical review processes to evaluate manuscripts for scientific accuracy, novelty, and importance; policies and practices that ensure that authors disclose all relevant financial associations and that such associations do not in any way affect the content published by the journal.

When developing the strategy and layout of the publication, we studied and analyzed the professional materials available to us from information resources of publishers and owners of bibliographic and abstract databases-leaders of international citation systems for relevant branches of science and groups of scientific specialties.

In the course of this work, three groups of scientific specialties were identified, which, in our opinion, made it possible to create a publication's rubricator and determine its name: "Pharmacy Formulas". At the same time, we took into account the definition of pharmacy as the entire life cycle of medicines, including the creation, preclinical and clinical research, production technology, organization of pharmaceutical business, as well as issues of control and analytical research, food and environmental safety. In turn, the word "formulas" means directions, trends, trends in the development of scientific and practical areas that make up pharmacy.

We believe that through our efforts, the journal will keep healthcare and pharmaceutical industry professionals at the forefront of medical and pharmaceutical knowledge, help them deepen their understanding of new areas of interest, and provide valuable insights into scientific and practical medical and pharmaceutical activities.

Authors and readers

To present the results of high-quality scientific research to the reader, we are ready to be responsible for preparing the manuscript to meet the requirements of the journal, quality review of manuscripts , preparing the article for publication, providing opportunities and scientific communications of the founders of the publication to promote the article.

The journal's website meets all the requirements of the international bibliographic database. Full electronic document flow for authors, reviewers, scientific and literary editors is carried out on our own platform.

To promote the article, authors will be able to use the personal website of the publication; assignment of the DOI identifier of the author's manuscript immediately after uploading to the site; unique author ID ORCID; professional social networks Google Scholar, ResearchGate; repositories; open electronic archives; bibliography management system; social media; registration of the scientist as a reviewer; assistance in preparing the use of media (materials for press releases, interviews).

The publishing house of the journal has direct channels for transmitting information to the RSCI and international databases: Scopus, Web of Science, PubMed, CNKI.

When developing all the tasks facing the members of the editorial Board and editorial Board of the journal "Formulas of Pharmacy", we share a common goal: to promote and actively participate in scientific communications on the declared groups of scientific specialties in the biomedical field and pharmacy, from the idea to the release of medicines to the consumer market and management of their waste and metabolites.

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Current Issue

Vol 7, No 2 (2025)

Pharmaceutical Sciences

Modern Antidepressants: A Comparative Analysis of Efficacy and Safety, Prospects for Studying New Drugs
Pavlova T.A., Telepina M.A., Perelygin V.V., Smetannikova E.A., Sklyarova N.A., Orlova A.V.
Abstract

The article provides a review of modern scientific publications on the use of antidepressants with various mechanisms of action, considers the most frequently used drugs in clinical practice, their mechanism of action, tolerability profile, and drug safety. Approaches to choosing an antidepressant, considering the underlying disease and comorbidities, are examined. Data on the study of new alternative drugs with antidepressant action are presented. When choosing an antidepressant, it is necessary to consider the complexity and multifactorial nature of the clinical picture of each patient, requiring a strictly individualized approach. For rational therapy and optimization of clinical results, a deep understanding of the mechanisms of action, indications, potential side effects, and pharmacokinetic features of various classes of antidepressants is necessary. The emergence of drugs with a multimodal mechanism of action expands the possibilities for personalization of therapy, increasing the effectiveness of treatment not only for depressive and anxiety disorders but also for depressive syndrome occurring in somatic and neurological diseases. Further research on pharmacogenetic factors and the development of personalized approaches to the selection of antidepressants will open up new opportunities for improving therapy and improving the quality of life for patients.

Pharmacy Formulas. 2025;7(2):10-25
pages 10-25 views

Biomedical Sciences

Neurodegenerative Disease Prevention: Synergistic Effects of Micronutrients and a Healthy Lifestyle
Lapshina O.V.
Abstract

Cognitive impairment, including dementia, represents a key challenge for modern healthcare amid global population aging. This paper provides a comprehensive analysis of the causes, risk factors, and prevention strategies for cognitive disorders. Special attention is given to non-pharmacological approaches aimed at enhancing intellectual, physical, and social activity, which help build cognitive reserve and slow neurodegenerative processes. The role of modifiable risk factors—such as arterial hypertension, diabetes mellitus, physical inactivity, depression, and social isolation—is examined, noting that addressing these factors could reduce the incidence of dementia by up to 40%. Particular attention is devoted to the use of micronutrients (B vitamins, omega-3 fatty acids, antioxidants) that possess neuroprotective properties, including protection against oxidative stress, improvement of neuronal communication, and reduction of neuroinflammation. Based on current data, the paper underscores the necessity of initiating prevention early in young and middle age to achieve healthy cognitive longevity. The work emphasizes the importance of a personalized approach and the need for further research to optimize strategies for maintaining mental health.

Pharmacy Formulas. 2025;7(2):36-49
pages 36-49 views
Reading Literacy for Sustaining Cognitive Reserve and Preventing Dementia Across the Lifespan
Tolstenko S.A.
Abstract

Reading literacy is a critical factor in healthy lifestyles and quality of life, as it has a positive impact on overall body health and cognitive functioning of the brain. Current research indicates a direct correlation between the degree of reading literacy and a reduction in the risk of central nervous system disorders characteristic of old age. Given the growing trend of population aging and the increasing number of patients with age-related diseases such as Alzheimer's disease and vascular dementia, the study of ways to develop sustainable reading skills is of particular importance. This work presents a review of studies on the influence of reading and other forms of intellectual activity on cognitive health and longevity. Various methodological techniques for developing reading literacy are analyzed, including clustering, reading with stops, crosswords, and the "thin and thick" questions technique, as well as their effectiveness in the context of maintaining active cognitive functioning in older age. Special attention is paid to the possibilities of implementing innovative approaches to organizing the reading process and adult education, with the aim of developing practical recommendations for educational institutions and social services aimed at maintaining cognitive health and promoting active aging. The results of this study are intended to raise awareness of the importance of reading literacy and to develop effective strategies for its development and maintenance throughout life.

Pharmacy Formulas. 2025;7(2):26-35
pages 26-35 views

Biological sciences

Mushrooms and Plants – Natural Sources of Healthy Longevity
Klemper A.V.
Abstract

A brief overview of plants and fungi as sources of essential beneficial dietary components – fibers, vitamins, macro- and microelements, as well as certain biologically active substances – is presented. Among plant fibers, insoluble cellulosic fibers, including lignified ones, and partially or completely soluble pectins and mucilaginous polysaccharides are characterized. Among fungal fibers, insoluble chitinous straight fibers and swelling, spiraled glycans are characterized. Tables with plant and fungal species containing maximum concentrations of these components, as well as types of biological activity of edible plant and fungal fibers and other groups of substances, are provided. For plants, flavonoids and related compounds, oils with polyunsaturated fatty acids (“omega-3”), essential oils, and steroidal saponins are also considered. For fungi, beneficial types of activity for groups such as proteins, lectins, terpenoids, terphenyls, lovastatin, and ergothioneine are presented. It is shown that the types of activity of plant substances are diverse, while fungal compounds are characterized by immunostimulating, antitumor, antioxidant, and bactericidal effects.

Pharmacy Formulas. 2025;7(2):50-60
pages 50-60 views
Species Composition and Resource Potential of Medicinal Plants in Spruce Forests of the Leningrad Region
Gryazkin A.V., Paramonov S.G., Voldaev L.K., Shmelev G.B., Kashafyev I.R.
Abstract

Data on the composition of the main types of medicinal plants growing in forested areas in the north-west of Russia are presented. The object of research is raw materials plants of the forest fund. Resource plant species were accounted for using a circular platform method with a radius of 178.5 cm (10 m2). At each accounting site, all species of plants were taken into account and the amount of projective coverage was set for each species. Based on the results of accounting work, the occurrence of each species at the study site was determined. According to the magnitude of occurrence and projective coverage, a conclusion was made about the abundance of this species and the prospects for its industrial harvesting. In total, 32 species of vascular plants and 8 species of mosses and lichens were identified under the canopy of acidic spruce. Of these, 18 species of vascular plants are classified as medicinal plants. Only 3 types are suitable for procurement.

Pharmacy Formulas. 2025;7(2):62-68
pages 62-68 views

Actual problems: discussion tribune

Harvesting and Cultivation of Medicinal Plants as a Health-Preserving Practice and a Form of Responsible Nature Management
Paramonov S.G., Kudryavtseva D.M.
Abstract

The article addresses the relevant issue of self-harvesting medicinal plants as a form of hobby that holds significant potential for health promotion and the development of ecological culture. It analyzes contemporary scientific publications emphasizing the need for a responsible and informed approach to this practice, based on knowledge of botany and ecology, support from like-minded communities, and legislative regulation. It is noted that only a comprehensive combination of educational activities, social interaction, and legal control can ensure the safe use of medicinal plant raw materials, preserve biodiversity, and minimize health risks to humans. The article discusses the advantages and potential dangers of self-harvesting medicinal plants, making it an important contribution to the development of health-preserving technologies and sustainable natural resource management.

Pharmacy Formulas. 2025;7(2):70-75
pages 70-75 views
Investigating the Negative Impacts of Medical Waste on Aquatic Ecosystems – An Increasing Hazard to Water Resources and Public Health
Kolgan N.R., Sklyarova N.A.
Abstract

This paper analyzes the literature data on methods for medical waste disposal and assessment of their impact on water bodies within the context of the existing legal and regulatory framework. The relevance of the topic is due to the increasing volumes of such waste and its potential danger to the population and ecosystems. The aim of the work is to systematize and evaluate approaches to disposal and methods for analyzing water body pollution. The work was carried out as part of the research topic of the Department of Industrial Ecology, aimed at developing theoretical approaches to justifying sanitary standards for the content of medicines and their metabolites in drinking water. Determining the degree of hazard of medical waste, which is the result of this study, is necessary for the development of sound and effective strategies to reduce their negative impact on the environment and human health. The acquired understanding of the problem serves as a solid foundation for further research aimed at improving methods for managing and disposing of medical waste.

Pharmacy Formulas. 2025;7(2):76-83
pages 76-83 views

Information and Prevention

The impact of risk-based occupational health and safety on employee health, longevity, and cognitive well-being
Solomatin I.A., Smirnova E.E., Telepina M.A.
Abstract

This article examines the impact of a risk-oriented approach to occupational health and safety on the health, longevity, and cognitive well-being of workers in the context of contemporary labor market challenges. The relevance of this topic is driven by a shortage of skilled labor, an aging workforce, and a growing focus among job seekers on working conditions and their effects on health. The research aims to substantiate the effectiveness of a risk-oriented approach as a strategy for ensuring safety, preserving health, and maintaining the cognitive functions of workers throughout their working lives. Based on the analysis of statistical data on occupational injuries over recent years, the implementation of a risk-oriented approach is shown to contribute to a reduction in the incidence of injuries and occupational diseases. It is emphasized that effective assessment and management of occupational risks enable the timely neutralization of hazards and the prevention of accidents, which, in turn, has a positive impact on workers' health and longevity. Particular attention is paid to the influence of working conditions on workers' cognitive functions and the need for the prevention of cognitive impairments associated with chronic stress, fatigue, and other adverse factors in the work environment. The research findings confirm the importance of a risk-oriented approach in ensuring safe and healthy working conditions, promoting the preservation of working capacity, cognitive well-being, and increasing the duration of workers' active lives.

Pharmacy Formulas. 2025;7(2):84-93
pages 84-93 views

Heritage

Dedicated to the memory of Professor Vladislav A. Kraus, a leading figure in neuropharmacology
Okovityi S.V., Napalkova S.M., Ivkin D.Y., Dyachkova E.D.
Abstract

This brief sketch is dedicated to the life and scientific work of pharmacologist Vladislav Alekseevich Kraus, who made significant contributions to the study of the functional organization of the brain and the mechanisms of memory. It outlines the main stages of his professional career, from his studies at the Leningrad Sanitary-Hygienic Medical Institute and postgraduate studies at the Institute of Experimental Medicine of the USSR Academy of Medical Sciences, to his headship of the pharmacology departments of the Orenburg and Dnepropetrovsk Medical Institutes, and his leadership of a laboratory at the Research Institute of Industrial and Marine Medicine in St. Petersburg. Particular attention is paid to the period of V.A. Kraus's work at St. Petersburg State Chemical Pharmaceutical University (SPCPA), where he engaged in pedagogical activity for over 20 years and contributed to the training of pharmaceutical personnel. The main scientific achievements of V.A. Kraus are presented, including the establishment of mechanisms of drug action on neurotransmitter systems, the reproduction of memory engrams, and energy metabolism in the brain. His research is highlighted, focusing on the study of the effects of psychotropic drugs, hemoperfusion, arginine vasopressin, and other compounds on the nervous system and cognitive functions.

Pharmacy Formulas. 2025;7(2):99-104
pages 99-104 views