Vol 63, No 6 (2014)

Articles
Prevention of neonatal group B streptococcal infections
Shipitsyna E.V., Savicheva A.M.

Abstract

Group B streptococcal infections (GBS) are the leading cause of sepsis, pneumonia and meningitis in infants during the first three months of life. GBS infections presenting within the first week of life are designated early-onset diseases, and those affecting infants between one week and three months - late-onset diseases. Intrapartum intravenous administration of antibiotics to women at high risk of transmitting the microorganism to the infants is currently considered the most effective method of prevention of early-onset GBS infections, and universal screening for GBS in late pregnancy - as the most effective method to detect women to whom antibiotic prophylaxis is indicated. Vaccination of pregnant women appears to be a promising approach to prevent both early- and late-onset GBS infections in infants, as well as GBS-associated diseases in women.
Journal of obstetrics and women's diseases. 2014;63(6):4-14
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Diagnosis and prediction of acute endometritis according to informative features of cell immunity
Agarkov N.M., Afanasova E.P., Budnik I.V.

Abstract

Immunosuppression of all the research features of cell immunity, high values of displacement and disintegration of T-helpers, citotoxi T-lymphocyte and natural killers, the increase of correlation among cell immunity components were revealed at 78 patients with acute endometritis by indirect immunophluoresent method. According to intermodal points of displacement, disintegration, information, modeling of clinical situation and correlation connections on a system level the main diagnostic features of acute endometritis are absolute and relative number of T-helpers, absolute content of natural helpers. The definition of the 3 above mentioned points of cell immunity would help to cut down financial expenses and prediction of acute endometritis easier.
Journal of obstetrics and women's diseases. 2014;63(6):15-20
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Laparoscopic hysterectomy for endometrial carcinoma in obese patients
Berlev I.V., Ul’rikh E.A., Aminzhon B.S., Nekrasova E.A., Mikaya N.A., Urmancheeva A.F., Tsipurdeeva A.A.

Abstract

Background. Up to date the coincidence of endometrial carcinoma and obesity is widespread. Obesity has unfavorable action on surgical treatment results. Objective. To evaluate the effectiveness of laparoscopic technique for surgical treatment of endometrial carcinoma in obese patients. Methods. We have prospectively evaluated the results of surgical treatment from 97 obese patients with low metastasis risk endometrial carcinoma from 2010 to 2014 years. Results. Laparoscopic surgery associated with low intraoperative blood loss (26.4 ± 7.1 ml vs 267.2 ± 45.0 ml, p < 0.0001), on the other hand laparoscopic surgery not prolongs operating time (108.8 ± 7.5 min vs 104.3 ± 13.5 min, p = 0.38). Obese patients after laparoscopic surgery have low complications rate (1.5 % vs. 48.3 %, p = 0.002). Conclusions. Laparoscopy is effective option for surgical treatment of low metastasis risk endometrial cancer patients with obesity.
Journal of obstetrics and women's diseases. 2014;63(6):21-31
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Features experiences gynecological patients in the preoperative period
Bloch M.E.

Abstract

The article presents study of the emotional and cognitive components of experiences gynecological patients in the preoperative period in order to allocate targets of psychological help to optimize the postoperative period and adaptation. Marked types of stress reactions, styles relations to illness, features depression and disturbing disorders in the study group.
Journal of obstetrics and women's diseases. 2014;63(6):32-37
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Human papillomavirus: screening and vaccination
Roik E.E., Baranov A.N., Usynin M.V.

Abstract

Every year, 500 000 women worldwide are diagnosed with cervical cancer. Currently, there is no doubt that certain types of human papillomavirus (HPV) do act as causative agents of cervical cancer. Nowadays there are more than 150 different types of HPV are known. Certain types of viruses by affecting the epithelium of humans and animals lead to appearance of warts or papillomas, others lead to malignancy of squamous epithelium. The most common HPV types are 16 and 18, cause cervical cancer. Vaccination and screening are the most effective tools for preventing cervical cancer. Preventive vaccines are currently registered and actively used in many countries around the world.
Journal of obstetrics and women's diseases. 2014;63(6):38-43
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Endothelial dysfunction in pathogenesis of preeclampsia
Makulova M.V.

Abstract

Preeclampsia is a severe complication of 2-25 % of pregnancies. Causes and mechanisms of preeclampsia are still unclear. Researchers treat endothelial dysfunction like the main cause of pathological disturbances that determine the severity of preeclampsia clinical symptoms. The main objective of this review is to summarize the researches datas of endothelial dysfunction in preeclampsia development.
Journal of obstetrics and women's diseases. 2014;63(6):44-54
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Liver steatosis at women with obesity. The features of pregnancy
Rzaeva R.N., Mozgovaya E.V., Palgova L.K.

Abstract

The article presents the features of the course of non-alcoholic fatty liver disease in obese patients, the mechanisms of this pathology and the impact of this condition during pregnancy. Much attention is paid to disorders of fat metabolism, which contribute to a complicated course of gestation, increasing the possibility of development of placental insufficiency, miscarriages, preeclampsia and generally have a negative impact on perinatal outcomes. Modern diagnostics and correction of these disorders are discussed.
Journal of obstetrics and women's diseases. 2014;63(6):55-65
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First-trimester medical abortion
Sukhikh G.T., Serov V.N., Prilepskaya V.N., Khan N.E., Tutunnik V.L., Baranov I.I., Baev O.R., Shmakov R.G., Tetruashvili N.K., Klimenchenko N.I., Kuzemin A.A., Astakhova T.M., Balushkina A.A., Aylamazyan E.K., Tarasova M.A., Krasnopolskiy V.I., Logutova L.S., Melnik T.N.

Abstract

The Clinical Protocol “First-Trimester Medical Abortion” is written in accordance with the Russian laws on health protection, Procedure on medical care provision to women seeking for artificial termination of pregnancy, Law on drug circulation. The evidential base for the clinical protocol was constituted by the publications included in the Cochrane Library, PUBMED and MEDLINE databases, by the results of the Russian clinical studies on the medical abortion carried out with the permission of the Ethical Committee of the Ministry of Healthcare of the Russian Federation, by the Russian and international regulatory documents on safe abortion (FDA, HAS). The objective of these clinical protocol is to improve the quality of medical aid in the Russian Federation provided during early pregnancy termination. The comments were discussed jointly by the work group members; a consensus was reached on the key questions of the clinical protocol and practical recommendations were developed.
Journal of obstetrics and women's diseases. 2014;63(6):66-86
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