Pleuropulmonary blastoma: case report in a child 8 years old
- 作者: Zaripova Y.R.1, Muss E.A.2, Arsentev V.G.3
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隶属关系:
- Petrozavodsk State University
- Sortavala Central District Hospital
- Kirov Military Medical Academy
- 期: 卷 13, 编号 4 (2022)
- 页面: 83-92
- 栏目: Clinical observation
- URL: https://journals.eco-vector.com/pediatr/article/view/114938
- DOI: https://doi.org/10.17816/PED13483-92
- ID: 114938
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详细
Pleuropulmonary blastoma is a very rare primary fetal tumor of the lung and pleura in young children and is associated with a mutation in the DICER1 gene. Based on the histological picture, three types of this tumor are distinguished: cystic (type I), solid cystic (II), solid (type III). Treatment is surgical followed by polychemotherapy. The prognosis is unfavorable.
The authors bring to the attention of colleagues a description of a clinical case of pleuropulmonary blastoma in an 8-year-old child, diagnosed against the background of an acute respiratory viral infection. He fell ill acutely with a rise in temperature and an unproductive cough. The condition was regarded as a course of an acute respiratory viral infection, symptomatic therapy was carried out. After 8 days from the onset of respiratory viral infection, there is a sharp deterioration in the condition in the form of shortness of breath, refusal to eat and drink, and weakness. The child is hospitalized in a Central District Hospital, differential diagnosis with pneumonia is carried out. According to the examination (plain radiograph and CT scan of the chest), a large volumetric formation with even contours is visualized in the right lung. The patient is transferred to a specialized hospital in St. Petersburg. After an MRI of the chest organs with contrast, taking a biopsy material and performing a histological examination, the patient was diagnosed with a tumor of the right lung — pleuropulmonary blastoma type II.
This clinical case of a rare malignant tumor in an 8-year-old child with congenital heart disease and cerebral palsy may demonstrate a severe variant of systemic connective tissue dysplasia and gene mutation.
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作者简介
Yuliya Zaripova
Petrozavodsk State University
编辑信件的主要联系方式.
Email: julzar@mail.ru
ORCID iD: 0000-0002-6907-2382
MD, PhD, Dr. Sci. (Med.), Head of the Department of Pediatrics and Pediatric Surgery, School of Medicine
俄罗斯联邦, Petrozavodsk, Republic of KareliaElena Muss
Sortavala Central District Hospital
Email: super.babydoc@yandex.ru
ORCID iD: 0000-0003-1804-0820
Head of the Pediatric Department. Sortavala Central District Hospital
俄罗斯联邦, Sortavala, Republic of KareliaVadim Arsentev
Kirov Military Medical Academy
Email: rainman63@mail.ru
ORCID iD: 0000-0002-3135-0412
MD, PhD, Dr. Sci. (Med.), Head of the Department of Children's Diseases
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