Vol 7, No 4 (2016)
- Year: 2016
- Articles: 20
- URL: https://journals.eco-vector.com/pediatr/issue/view/346
Articles
Multiorgan violations in connective tissue dysplasia in children. diagnostic and management standards. Russian draft recommendations
Abstract
Comparative Analysis of Effectiveness of Lung Sonography and Chest Radiography for Diagnosis of Lung Diseases in Infants
Abstract
Autosomal-recessive polycystic kidney disease in children
Abstract
The aim of the study was to assess the features of development of renal and extrarenal cysts, arterial hypertension, syndrome of portal hypertension in autosomal recessive polycystic kidney disease (ARPKD) in children. Patients and methods. With the aim of establishing the type of inheritance of polycystic kidney disease the genealogical analysis of 12 families, clinical ultrasound of the kidneys and abdominal organs, computed tomography. The study included 14 children with ARPKD. Conducted follow-up study of 14 children with ARPKD to determine the age by the detection of cysts based on ultrasound, the features of the initial clinical manifestations and course, complications and outcome.
Results: the Age of the children back to the time of detection of the cysts in the kidneys based on ultrasound when ARPKD was 2.3 ± 0.4 month. Identified a high incidence of arterial hypertension in neonates and infants with ARPKD at 92.9%. Extrarenal location of the cysts is set at 71.4%. Syndrome of portal hypertension, bleeding from varicose veins of esophagus and stomach, melanau installed in 5 (35,7%) children. Of the 14 in 5 (35,7%) patients diagnosed ARPKD children with liver fibrosis, which has a favorable prognosis without the formation of renal failure in infants and early childhood, 9 (64,3%) diagnosed with classic ARPKD in neonates and infants that is characterized by progression to end-stage renal disease in the first year of life.
Features gastroduodenal pathology in military age patients with malnutrition
Abstract
Background.Digestive diseases are a leading cause of body weight deficit and has a leading position among general morbidity in young patients.
Purpose.To analyze the pathology of the upper digestive tract in young men with a low body weight.Material and methods.193 young men aged 16-27 y.o. (mean age 20,3±2,2 years) with a mean body mass index (BMI) 17,8±2,4 kg/m2were examined. Erosive lesions of the stomach were found in 18,8% (n=36) and erosive lesions of the duodenum – in 16,1% (n=31). Ucer of duodenum were found in 11,4% (n=22) and none of stomach. Duodenal reflux were found in (51,8%;n=100) and every fourth was combined with erosive gastritis. Histological examination of stomach revealed an inflammation in all cases. Atrophic changes in the antral stomach were detected in 11% (n=6) of the cases. All cases of atrophy accompanied by HP colonization. In the group with normal BMI the prevalence of cardia failure, erosive lesions of the esophagus, stomach and duodenum were founded. In the same group there were prevalence of stomach inflammation by histology (44%). The patients with low BMI (hypotrophy 1 degree) have less erosion and inflammation compare to patients with normal BMI and hypotrophy 2-3 degrees.
Conclusions.1. Stomach inflammation were revealed in the majority of young men with low BMI. Atrophic changes of gastric antrum associated with HP infection were found in 10% of cases. 2. Erosive lesions of the esophagus, stomach and duodenal are associated with the BMI. This finding allows use the BMI as an integral indicator of the severity of the inflammation of stomach and duodenum. Erosive lesions of the upper digestive tract are found predominantly in patients with normal BMI.
Noncarrying Оf Pregnancy In Women Оf Different Body Types
Abstract
IgE-hypersensitivity to allergens of the fungi Rhizopus Nigricans and Cladosporium Herbarum in childrenwith respiratory allergies
Abstract
Clinical characteristics of newborn with different birth weight (results of a multicenter cohort study)
Abstract
Vegetative disfunction and adaptive reserve potential in children born with fetus growth delay in the first 6 months of life
Abstract
Structural and functional state of arteries in women with metabolic syndrome associated with autoimmune thyroiditis
Abstract
The aim of the research was to study structural and functional state of arteries in women with metabolic syndrome (MS) associated to autoimmune thyroiditis (AIT), to improve the efficiency of therapeutic and preventive measures. The study sample included 108 women, 40 of them were with metabolic syndrome, autoimmune thyroiditis and euthyroidism (group I), the second group consisted of 31 women with metabolic syndrome, autoimmune thyroiditis and subclinical hypothyroidism (group II) and control group included 37 women with metabolic syndrome without thyroid disease. Laboratory examination included the study of lipid profile ( cholesterol, low-density lipoproteins, LDL Very Low Density Lipoprotein, VLDL, high-density lipoproteins, HDL, triglycerides, atherogenic index), thyroid hormone levels (ATPO and ATG, fТ4, T3) and thyroid stimulating hormone (TSH). Also, patients were instrumental examination with ultrasound of the brachial artery to assess endothelium dependent and endothelium independent relaxation, the definition of complex intima-media thickness. In addition, it performed ultrasound of the kidneys with renal artery duplex scanning with the assessment of renovascular hemodynamics. All patients of the research showed elevated arterial stiffness endothelial dysfunction and remodeling of the vascular wall. These changes are most pronounced in women with metabolic syndrome associated with autoimmune thyroiditis and subclinical hypothyroidism.
Manifestation of cardiomyopathy in patients with Marfan syndrome and marfanoid habitus
Abstract
Marfan syndrome is a common genetically determined pathology of connective tissue. It was showed a reduction in systolic and diastolic left ventricular function in patients with Marfan syndrome, as well as the increase in left ventricle size, regardless of previous surgical intervention. Now in literature use the term “cardiomyopathy in Marfan syndrome,” denoting changes of the left ventricular function, in the absence of hemodynamic reasons for its deterioration. In this paper we evaluated the morphological and functional characteristics of the left ventricle, not only in patients with Marfan syndrome, but also in patients with marfanoid habitus.
Materials and methods. The study included 98 people, 8 of them – patients with Marfan syndrome, 24 examinees with marfanoid habitus and 66 healthy examinees – control group. To all patients entered into the study, echocardiography was performed. Additionally global and local deformation of the myocardium using techniques speckle tracking was assessed.Resultssignificant difference circumferental deformation parameters of the anterior and lateral walls of the left ventricle and its statistically significant reduction in the group with marfanoid habitus was obtained.
Conclusionsimpaired regional contractility may be the first sign of cardiomyopathy in patients with Marfan syndrome and in such a dysplastic phenotype as marfanoid habitus that is likely associated with hereditary disorders of the structure and function of connective tissue in various states of dysplastic phenotipes.
Factors Affect on development and clinical course of ischemic stroke in children
Abstract
Medical Illiteracy of Parents and its Impact on Children’s Health
Abstract
Purpose —to find out the impact of the medical illiteracy of parents on children’s health.
Materials and Methods:the research method —a questionnaire. Questionnaires distributed among parents of children of all ages —between one year old and seventeen. Analyzed 564 questionnaires. It was indicated the position witnessing about the medical illiteracy of parents. Determined medical illiteracy of parents group and detected medical illiteracy of parents coefficient.
Data.It was found that in the group of medical illiteracy of parents complaints about the health of children was significantly more than in the group without an medical illiteracy of parents and in the total sample. The incidence of bronchitis, pneumonia, tonsillitis (chronic tonsillitis) and children’s infections in the group with the medical illiteracy of parents significantly more than in the whole sample and the group without medical illiteracy of parents. Children from group with medical illiteracy of parents significantly more often complain and consist at a dispensary. In the subgroup of medical illiteracy of parents with a high coefficient obtained even higher morbidity rates. Communication between medical illiteracy of parents and the pathology of pregnancy, the incidence of ARVI and the frequency of antibiotics absent.
Conclusions.The revealed regularities allow to predict the possible violations in the health status of children with medical illiteracy of parents, depending on the coefficient.
The role of local anesthesia to reduce pain after PСNL
Abstract
The goal of the study was to assess the level of postoperative pain in patients undergoing PCNL after paratubal infiltration with local anesthetic to compare this method of anesthesia with a control group where local anesthesia was not provided. 63 patients were included with kidney stones, confirmed by computer tomography (CT), who were planned to undergo percutaneous nephrolithitomy (PСNL). During the observation 6 patients have been excluded in accordance with the exclusion criteria. The remaining 57 patients were randomized into 2 groups: group A (n= 28) at the end of the operation received paratubal infiltration of 0.5% sol. ropivacaine; group B (n= 29) (controls) — local anesthesia was not used. Postoperative pain was assessed by means of VAS-score 1 hour, 6 hours and 24 hours after surgery. Systemic analgesia was performed with NSAIDs (intramuscular injection of 100 mg ketoprofen) when requested by the patient (Patient-Controlled Analgesia). In patients with local anesthesia, the total VAS score evaluated after 1 and 6 hours after the operation was significantly lower than in the control group. The average amount of ketoprofen required for postoperative analgesia in the group of patients with paratubal infiltration was significantly lower than in the control group. Paratubal infiltration of local anesthetic after PCNL significantly reduced postoperative pain and tended to reduce the amount of NSAIDs to eliminate pain, which in turn may reduce the risk of complications associated with NSAID.
Echocardiography in the differential diagnosis of patent ductus arteriosus in children
Abstract
The efficacy of treatment of early stage of iron-deficiency states in children
Abstract
Liver dysfunction in pathogenesis of burn disease and its correction with succinate-containing drugs
Abstract
Whole exome sequencing: principles and diagnostic capabilities
Abstract
The Clinical Case Of Symptomatic Epilepsy In Newborn With Neonatal Hypoglycemic Encephalopathy
Abstract
Colobomatous cysts of optic nerve
Abstract
Objectives of publication:presentation of a rare clinical observation from our own practice.
Key points:colobomatous orbital cyst with microphthalmos — rare anomaly of an embryonal development of an eyeball, it is formed owing to “filling” of an optic nerve with the intraocular liquid coming to him from a vitreous chamber through сoloboma of disk because of violation of hydrodynamics in a forward segment of an eye. Usually this anomaly is combined with microphthalmic eye, though cases of a colobomatous cyst with a normal size of an eyeball, and also with other anomalies of development of an eye (inferior uveoretinal coloboma, prepupillary membrane, corneal opacity) are described.
Сlinical observation:during 2015 in our department there were two children to whom after the carried-out inspection the diagnosis of a colobomatous cysts of optic nerve has been exposed. Concerning the first child waiting tactics has been recognized expedient, at repeated surveys in 1 and 4 months of any dynamics in the ophthalmologic status it hasn’t been revealed. To the second child because of the expressed exophthalmos with lagophthalmia, with perforation threat, surgical intervention – a puncture and drainage of a cyst of an optic nerve is performed. After operation the correct situation and mobility of an eyeball were restored, xerotic changes of a cornea and conjunctiva have decreased.
Conclusions:from the pathogenetic mechanism of cystous formation of an orbit, it is more logical to specify the clinical diagnosis a mention in him an optic nerve – “сolobomatous cysts of optic nerve”. Surgical treatment depends on the sizes of cyst, degree of exophthalmos and existence of complications.