Vol 23, No 6 (2012)

The paper gives data on the integration of basic science and practical medicine by the example of the work of the Research Institute of Uronephrology and Human Reproductive Health set up on the basis of the R.M. Fronshtein Urology Clinic, I.M. Sechenov First Moscow State Medical University, 19 months ago.

None of the world’s most used types of gastroenteric anastomosis at surgery for gastric cancer are devoid of defects. The choice of a gastrectomy method cannot be competitive and must come within the competence of a surgeon; at the same time it is imperative that the specific features of postoperative patient rehabilitation be kept in mind.

Eating disorders (EDs) are the complex problem which requires united efforts of psychiatrist and physicians of other specialties. Diuretic abuse is common in EDs, but it is only one of the aspects of their somatic complications. Treatment of diuretic abuse includes gradual drug withdrawal with monitoring of patients’ mental and somatic state.

The treatment of nephrogenic anemia may be unsafe, clearly manifesting itself when large-dose erythropoietic stimulants are used. In this case it is particularly important to estimate the expected benefits and risks of the therapy in a specific patient and the possibilities of reducing the dose of stimulants.

The experience with urologic care to inpatients with prostatitis in the presence of concomitant HIV infection has demonstrated that the prostate inflammatory process tends to form an abscess. The efficacy of antibacterial agents is also considered during empiric therapy for acute prostatitis or exacerbation of chronic prostatitis in the presence of HIV infection.

In 2005 to 2011, patients with primary premature ejaculation (n=38) underwent selective penile denervation with disintegrity of 50% of the penile dorsal nerves. The intervention performed could prevent impaired ejaculation in 89,5% of the patients. Postoperative complications (subcutaneous hematomas) were noted in 5,3% of the cases.

A retrospective multivariate analysis of the results of emergency urologic care to 115 patients with priapism could evaluate the efficiency of different surgical treatments and antibacterial prophylaxis during surgery for priapism.

The paper analyzes the results of a postoperative dynamic ultrasound (US) study in 79 patients with gastric cancer in the period 2004 to 2007. Its timely US diagnosis, the application of mini-invasive interventions could avoid resurgery and prevent early postoperative complications. A postoperative US study should be a standard examination method in patients within the first 24 hours after surgery.

The paper gives the results of using the original drug Venofer® to treat anemia in 146 patients with chronic renal disease, of whom 25 were on programmed hemodialysis (HD). The patients were followed up during a year, over which they received the original epoetin preparation Recormon subcutaneously and the orgininal iron drug Venofer ® intravenously. All the 146 patients with nephrogenic anemia who used epoetin preparations (Recormon) and intravenous iron (Venofer ®) could achieve the goal hemoglobin level of 110-120 mg/dl, thereafter the weekly dose of Recormon was halved compared to its starting dose of 60 IU/kg/week and the constancy of the body's iron level (TSAT>20%) in all the patients could be maintained with Venofer® 100 mg once every two weeks. In the patients on programmed HD, Venofer® was administered in a dose of 40 mg after each session or 100-200 mg once weekly. No serious complications were noted with the standard doses of Venofer ®.

Potassium and magnesium enter, in an important manner, into the regulation of cardiovascular and central nervous system functions, afford the normal course of numerous metabolic biochemical processes, control neuromuscular transmission, positively affect phosphorus and calcium metabolism, and maintain electrolyte balance in the body. Potassium and magnesium imbalance belongs to the most common electrolyte disorders. So the preparations of these macroelements are used in a wide range of indications in both the treatment of primarily cardiovascular diseases and the prevention of hypokalemia and hypomagnesemia particularly in patients taking diuretics (thiazide and especially loop ones) and/ or cardiac glycosides (digitalis preparations). It is appropriate to coadminister the salts of potassium and magnesium since the metabolism of the macroelements is closely related. Asparaginic acid potassium and magnesium salts have been widely used in clinical practice. Panangin is one of the most effective drugs that have a proper balance of potassium and magnesium.

An association was studied between endothelin-1 and resistin levels and insulin resistance in patients with varying degrees of carbohydrate metabolic disturbances. There was an elevated resistin level in women and in those with glucose intolerance (GI) or type 2 diabetes mellitus (DM) and in men with GI only. The most marked increase in endothelin-1 level was found in women with GI. The level of endothelin-1 was directly related to that of resistin in insulin-resistant men.

Are some facts about Z.V. Ermolyeva, known only to a narrow circle of specialists, and close friends.