Development of technology for obtaining a dry extract from the Scutellaria Iscanderi Juz. herb
- Authors: Muratova S.K.1, Ismailova M.G.2, Ismailova P.L.1, Khalilov R.M.3
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Affiliations:
- Uzbek Research Chemical-Pharmaceutical Institute named after A. Sultanov
- Tashkent Pharmaceutical Institute
- Institute of Chemistry of Plant Substances named after Academician S.Yu. Yunusov of the Academy of Sciences of the Republic of Uzbekistan
- Issue: Vol 72, No 4 (2023)
- Pages: 37-44
- Section: Technology of medicines
- URL: https://journals.eco-vector.com/0367-3014/article/view/567942
- DOI: https://doi.org/10.29296/25419218-2023-04-05
- ID: 567942
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Abstract
Introduction. Plants of the genus Scutellaria L. are widely used in medicine in the treatment of various diseases. One of the common species of the genus Scutellaria L. in Uzbekistan is Scutellaria Iscanderi Juz., which contains flavonoids, tannins and has an effective sedative effect.
Objective: to develop an optimal technology for the production of dry extract from the S. Iscanderi herb.
Material and methods. The object of the study is the S. Iscanderi herb, as well as liquid and dry extracts based on it. Determination of technological parameters of the extraction process was carried out in accordance with well-known methods. The quantitative content of the sum of flavonoids was determined by the spectrophotometric method, the content of tannins was determined by the method of volumetric permanganometric titration.
Results. A technology has been developed for obtaining a dry extract from the S. Iscanderi herb. The optimal extractant and extraction conditions were experimentally established.
Conclusion. The data on the substantiation of the technology for obtaining a dry extract from the S. Iscanderi herb is presented.
Keywords
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About the authors
Shakhnoza Khakimbaevna Muratova
Uzbek Research Chemical-Pharmaceutical Institute named after A. Sultanov
Author for correspondence.
Email: mshx2244@mail.ru
ORCID iD: 0000-0002-5510-5462
researcher
Uzbekistan, Do’rmon yo’li str, 40, Tashkent, 100125Mokhinur Gafurovna Ismailova
Tashkent Pharmaceutical Institute
Email: pharmokhinur@gmail.com
ORCID iD: 0000-0002-6739-4660
Doctor of Pharmaceutical Sciences, professor
Uzbekistan, Oybek str, 45, Tashkent, 100015Pazaat Lutpullaevna Ismailova
Uzbek Research Chemical-Pharmaceutical Institute named after A. Sultanov
Email: ipazaat@mail.ru
ORCID iD: 0000-0001-9987-5111
PhD in chemistry sciences, head of the laboratory
Uzbekistan, Do’rmon yo’li str, 40, Tashkent, 100125Ravshanjon Muratdjanovich Khalilov
Institute of Chemistry of Plant Substances named after Academician S.Yu. Yunusov of the Academy of Sciences of the Republic of Uzbekistan
Email: r.m.khalilov@mail.ru
ORCID iD: 0000-0003-0414-1049
Doctor of Technical sciences, leading researcher
Uzbekistan, Mirzo Ulugbek str, 77, Tashkent, 100170References
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