Kyphoscoliotic spinal deformities associated with high risk of developing neurological deficits. Literature review

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Abstract

This is a literature review on kyphoscoliotic deformities with a high risk of severe primary neurological deficit. The review is integrative in nature and was conducted using medical literature databases and search resources such as PubMed, Google Scholar, and eLibrary. The following aspects are covered: the etiology and pathogenesis of neurological deficits caused by the natural progression of deformities, the main principles, and directions of surgical treatment for neurologically complicated spinal deformities. The scientific literature describes the primary mechanisms of neurological deficit development: mechanical compression and traction of the spinal cord, as well as impaired circulation at the apex of the deformity. Surgical methods for treating neurologically complicated kyphotic and scoliotic deformities have evolved with advancements in spinal instrumentation and approaches. In the first half of the 20th century, various spinal canal decompression methods were described, including laminectomy, costotransversectomy, spinal cord mobilization, and spinal canal remodeling. In the second half of the 20th century, the development and active use of spinal instrumentation (sublaminar hooks, pedicle screws) enabled simultaneous decompression, fixation, stabilization, and correction of spinal deformities. Combining different stabilization and deformity correction methods with concurrent spinal canal decompression creates the conditions for restoring spinal cord function, leading to a regression of neurological deficits and preventing severe patient disability.

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About the authors

Anton G. Nazarenko

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

Email: nazarenkoag@cito-priorov.ru
ORCID iD: 0000-0003-1314-2887
SPIN-code: 1402-5186

MD, Dr. Sci. (Medicine), professor of RAS

Russian Federation, 10 Priorova str., 127299 Moscow

Alexander A. Kuleshov

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

Email: cito-spine@mail.ru
ORCID iD: 0000-0002-9526-8274
SPIN-code: 7052-0220

MD, Dr. Sci. (Medicine)

Russian Federation, 10 Priorova str., 127299 Moscow

Igor M. Militsa

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

Author for correspondence.
Email: igor.milica@mail.ru
ORCID iD: 0009-0005-9832-316X
SPIN-code: 4015-8113
Russian Federation, 10 Priorova str., 127299 Moscow

Marchel S. Vetrile

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

Email: vetrilams@cito-priorov.ru
ORCID iD: 0000-0001-6689-5220
SPIN-code: 9690-5117

MD, Cand. Sci. (Medicine)

Russian Federation, 10 Priorova str., 127299 Moscow

Igor N. Lisyansky

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

Email: lisigornik@list.ru
ORCID iD: 0000-0002-2479-4381
SPIN-code: 9845-1251

MD, Cand. Sci. (Medicine)

Russian Federation, 10 Priorova str., 127299 Moscow

Sergey N. Makarov

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

Email: moscow.makarov@gmail.com
ORCID iD: 0000-0003-0406-1997
SPIN-code: 2767-2429

MD, Cand. Sci. (Medicine)

Russian Federation, 10 Priorova str., 127299 Moscow

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Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. A schematic representation of kyphosis showing compression of the spinal cord in the area of the apex of the deformity. The dura is stretched and compresses the spinal cord relative to the anterior surface of the vertebral body in the area of the apex of the kyphosis. Note. ППС — anterior longitudinal ligament, ЗПС — posterior longitudinal ligament, TMO — dura mater.

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3. Fig. 2. a — computed tomography of the spine a�er bone transversectomy (from the author’s personal archive): dotted line — resection zone, yellow oval — new position of the spinal cord a�er surgery; b — schematic representation of the resection area when modeling the spinal canal [25].

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4. Fig. 3. Types of osteotomies according to Schwab [38].

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