Mycelial fungi using for secondary processing of medicinal plant raw materials

Currently, in the treatment of many chronic diseases, drugs based on medicinal plant raw materials are widely used. Modern herbal medicines, as a rule, combine high efficiency, relative safety and breadth of therapeutic action. In the production of many galenic and neogalenic preparations, in most cases, waste products of plant raw materials containing various biopolymers, including cellulose, the presence of which can, under certain conditions, induce the synthesis of the corresponding hydrolases - cellulases. The reviewed article is devoted to solving the actual problem of using mycelial fungi for secondary processing of medicinal plant raw materials. As an example of waste of plant raw materials, the authors used a schroth of roots and rhizomes of Rubia tinctorum, formed in the process of dry extract obtaining in the experimental production Department of All-Russian Scientific Institute of Medicinal and Aromatic Plants. A characteristic feature of various originschroth is a low fat content and a relatively high number of proteins and cellulose-containing substances. Previously, the authors showed that micromycetes from the VILAR collection have the ability to hydrolyze some insoluble proteins and various types of celluloses. In this regard, it is absolutely logical to try to use these biological objects for conversion of schroth. The article shows that all the studied mycelial fungi grew well on media with the replacement of easily metabolized carbohydrate with the schroth of the roots and rhizomes of Rubia tinctorum. Micromycetes formed lysis zones during surface cultivation, which indicates the synthesis and secretion of hydrolases into environment. In the result of a detailed study of 13 fungal strains, as well as regression and correlation analysis, were selected 5 micromycetes that are promising for secondary processing of medical plant raw materials.

micromycetes, hydrolases, plant raw material, Rubia tinctorum