Vol 4, No 4 (2007)

The article surveys generalized and systemized modern data on the influence of changes in neuroendocrine regulation of hydrocarbonate and lipid metabolism on women's reproductive function.

The effect lipid fraction of the balneotherapeutical medication "Elton" on inflamed cervix uteri is analyzed in this article. Time-related dynamics of the results of routine and special methods of examination is presented in the paper. Application of lipid fraction provides a decrease of duration of complex therapy of cervicites, normalizes local immunity indices and does not cause allergic reactions.

Patients with terminal chronic kidney disease (CKD) display immunity dysfunction, which is manifested by a lower production of high-affinity IgG to cytomegalovirus (CMV) and a weak activation of Th1 route of immune response. Administration of Cyclosporine after transplantation of a kidney leads to aggravated deficiency of antivirus immunity. This causes activation of viruses HSV 1,2 and CMV.

We revealed a positive influence of ultralow doses of antibodies (ULD) to C-ended fragment of receptor type 1 of the angiotension II on the course of chronic heart failure (CHF) due to diastolic dysfunction of the left ventricle in patients with chronic kidney disease (CKD) stage 5, who were on program hemodialysis (PHD). Inclusion of Cardos into standard therapy of CHF has yielded signs of improved relaxation indicators of the left ventricle; the patients' life quality improved as well; the severity of clinical presentations reduced.

Treatment of magnesium deficiency requires parenteral therapy but oral administration is indicated for most asymptomatic patients, especially in outpatient settings. Depending on the degree of compensation of systemic alimentary Mg deficiency in the red blood cells the investigated Mg salts may be ranged as follows: Mg (L-, D- and DL-) aspartate, Mg (L- and DL-) glutamate, Mg DL-pyroglutamate, Mg succinate, Mg glycinate, Mg citrate, Mg orotate, Mg taurate, Mg lactate.

Experiments on rats revealed that mexidol, semax, amtizol and the new drug IBCP-2 can considerably decrease neurological deficiency upon bilateral ligation of common carotid arteries. Besides, mexidol, semax, amtizol and IBCP-2 decreased death outcomes of rats considerably. The effect on neurological deficiency demonstrated by IBCP-2 exceeded the effect of other drugs considerably in most observed cases.

We investigated psychopharmacological profile of the new adenine derivative with antiviral activity. We revealed the antidepressant-like activity of this compound in the forced swimming test in doses of 1, 5, 10 and 50 mg/kg, with the maximum effect in doses of 1 and 5 mg/kg, that was confirmed on the model of reserpine depression in rats.

Age-related dynamics of the stromal and parenchymal interactions in the T- and B-cellular compartments of the splenic white pulp was elucidated using methods of immunohistochemistry.

The results of treatment of 146 patients with duodenal ulcer complicated by bleeding are investigated; these patients were observed in an active-passive manner. In 145 patients after endoscopic surgery for bleeding and antisecretory and replacement therapies with Losek and the Nexium it was possible to achieve reliable hemostasis from the bleeding duodenal ulcer and to avoid urgent surgery. Use of low-invasion methods of treatment of duodenal ulcer complicated by bleeding, allows surgeons to lower down the percent of postoperative complications and to reduce to a minimum the percent of relapses of peptic ulcer.

Using metabolic preparations - aminolonum, phenibitum, picamilonum - in the training process of tumblers contributes to their force and speed.

The paper presents data of suprasegmental cerebral activity of 108 children aged 8-12 with consequences of birth trauma of cervical part of the spine manifested as myofascial pain syndrome. According to the data of spino-bulbo-spinal reflexes in children of the second age period with consequences of birth trauma of cervical portion of the spine, formation of generators of pathologically elevated excitation with a higher level of reflex polysynaptic activity of the lower portions of brainstem caused myofascial pain syndrome on one side of the body. Clinical and electroneurophysiological correlation between the extent of polysynaptic reflex excitability of brainstem and the extent of myofascial pain syndrome in the superior quadrant of the body and in one side of the body was established. Comparison of the sides of the body revealed no changes of functional condition of brainstem in children without asymmetry of myofascial pain.

The article presents the results of the comparative analysis of clinical and laboratory indices in drug abusers with acute hepatitis C and non-abusing patients infected with hepatitis C virus. Several clinical, biochemical and immune changes in drug abusers were revealed. Greater persistence of symptoms of the disease and biochemical disorders, considerable changes of the antioxidant system such as an increase of antiradical enzyme activity, accumulation of lipid oxidation derivatives, immune insufficiency involving mainly T-cell disorders were found.

The article describes a new method of surgery for cystocele with discussion of 120 clinical cases. A higher efficiency of the new method is proved.