No 3 (2016)

Unplanned pregnancy and tuberculosis are extremely unfavorable combination. Therapeutic abortion in this situation may lead to the subsequent reproductive disorders. In pulmonary tuberculosis, this problem can be exacerbated by additional factors, such as comorbidity and multimorbidity. To avoid such situations, phthisiologist and obstetrician should choose an acceptable contraceptive drug with minimal risk for the patient, enabling maintenance of reproductive health and the prevention of pregnancy during the period of active treatment. Progestin-only oral contraceptives are safe in tuberculosis, sexually transmitted infections, HIV-infection/AIDS, diabetes mellitus, complications acquired valvular diseases, epilepsy, as well as during lactation. Use of progestin-only contraceptives greatly enhances reproductive planning in women with limitations or contraindications to the use of estrogens.

The article reviewed the literature data on the course of pregnancies, occurring with the help of assisted reproductive technologies, and their impact on perinatal outcomes.

Organization of proper nutrition for pregnant and lactating women is essential for the normal course and a successful outcome of pregnancy, provide adequate child development starting from the prenatal period, as well as maintaining the health of the woman. Planning food ration for pregnant woman should take into account both her physiological characteristics, and a set of external factors, including geographic location of living, the degree of physical activity, the presence of comorbidity, etc., which may affect the need for major macronutrients and micronutrients. The article discusses the existing norms of physiological needs for nutrients and energy for women of childbearing age, as well as the recommended average daily set of products compiled by taking into account the health status, stage of pregnancy, and lactation.

Hysteromyoma is one of the most common disease among women of reproductive age and often causes a variety of disorders, including infertility. This leads to the need for organ-preserving surgical treatment. Today, our understanding of the impact of different types of interventions on the receptor properties of the endometrium is limited. This article presents the results of the evaluation of the expression of endometrial receptivity markers, both progesterone and estradiol receptors, Noha-10 and BCL-2 genes, leukemia inhibitory factor and pinopods, in patients undergoing conservative myomectomy.

The article considers the evaluation of the effectiveness of estrogen-gestagen therapy in the treatment of articular syndrome in menopausal women. Our study showed no negative impact of estrogen-gestagen drugs in clinical manifestations of postmenopausal osteoarthritis. It was concluded that early administration of an estrogen-gestagen therapy in menopausal women for the prevention of clinical manifestations of articular syndrome is feasible.

The article describes the results of the retrospective application of in vitro fertilization/intracytoplasmic sperm injection in 31 female patients with a body mass index> 25 kg/m2 (38 stimulation cycles) compared to a control group of 20 patients with normal body weight. Indications for the use of assisted reproductive technology included tubal-peritoneal infertility due to obstruction or lack of uterine tubes or male infertility. The features of superovulation stimulation and clinical outcomes were accessed, as well as the frequency of ovarian hyperstimulation syndrome, depending on the presence of obesity, type of fat deposits, the presence of the metabolic syndrome and polycystic ovary syndrome.

The article analyzes the incidence of HPV (Human Papilloma Virus) infection among Perm female students and schoolgirls. The advisability of the introduction of HPV testing as a mass screening to identify high-risk groups for cervical cancer pathology is demonstrated. The data of the evaluation of the efficacy of inosine pranobex in the treatment of clinical forms of human papillomavirus infection in women of young childbearing age are presented. A comparison of the effectiveness of the drug in monotherapy and as part of complex treatment is performed.

This article presents an overview of current literature data on obstructive azoospermia. The results of the study to assess the effectiveness of different methods of sampling sperm in patients with obstructive azoospermia depending on the etiology of the obstruction are discussed. The data obtained allow a selective approach to the choice of biopsy method for such category of patients.