Vol 3, No 4 (2015)

We have conducted morphological and anatomical studies of Juniperus communis, revealed diagnostic indices of the stamina, stalk, and needle. The leaf is sessile, linear awe shaped, pointed. Stalk form at cross section is cylindrical. Needles are lanceolar with one whitish vertical stripe, with paracytic stomata.

This article presents an experimental study of choice of flavorings and sweeteners for taste correction of oral gels. We have shown the possibility of changing of organoleptic properties for drugs with weak and strong unpleasant odor and taste.

We have conducted a study about the influence of natural flavonoids of phloridzine and icariins on the working capacity and a state of neurological status of animals in conditions of long exhausting physical and psy-choemotional stresses. We have used outbred male mice weighing 20-25 g in the experiment. The compounds under study were administered per os at dose of 100 mg/kg 60 minutes before the stresses modeling. Physical and psychoemotional stresses were modeled on a forced swimming test with 20% stress from an animal weight during 10 days. After that psychoemotional state of animals was evaluated in tests of “open field” and “elevated plus maze”. As the result of the experiment, we have established that phloridzine application conduced the increase of working capacity of animals, while activity peak fell on the 7 th day of administration with stable indices, which characterized psychoemotional state of animals. The administration of icariin led to the working capacity reduction of mice by 44.6%

Last decades the amount of people with thynoid gland diseases has increased significantly all over the globe. This disease has more negative consequences for women organism during all aging hormonal changes. Similarity of symptoms of thynoid glands diseases and a range of aging hormonal changes complicates the problem. At that the question of pharmaceutical assistance for women with this pathology was not the object of organizational and economical researches in the Russian Federation, despite their relevance. The purpose is the study of a degree of scientific development of the mentioned problem and representation of the elements of problem situation in the chosen segment of medical and pharmaceutical assistance consumers. Based on the analysis of literature and statistic data, content analysis of rules and regulations, concerning procedures and the relations in the pharmaceutical assistance system, and the results of the conducted sociological survey, we have formed the elements of a problem situation in the chosen segment of medical and pharmaceutical support consumers. Sociological, graphic, logic, content-analysis were used as methods of the study. We have substantiated a scientific and practice need in development of methodological principals of pharmaceutical support optimization for women with thynoid gland pathology; we have reasoned the opportunities and principal directions of specialized pharmaceutical assistance to the given segment of drug consumers. We have proved the timeliness of the study for organization of pharmaceutical assistance for women with thynoid gland pathology due to its specifically negative consequences during all aging hormonal changes in an organism. We have revealed the presence of risk factors and exceptionally low awareness of women in thynoid gland pathology against the background of excessive occupation of women in active working ages. We have determined a niche in formation of informational mass with available content to inform the population about the markers of thynoid gland functions disorders and methods of their prevention.

Active influence of external environment on pharmaceutical activity, and the inner processes in pharmaceutical organizations may be accompanied with certain threats appearance for economical state of an organization. In this connection, there is an objective need in administering of the safety for a pharmaceutical organization and its management basing on the corresponding knowledge. Formation of conceptual model of economical safety management of a pharmaceutical organization is the purpose of this study. Using logic analysis and generalization of literature data and the results of our studies for economical safety of pharmaceutical organizations we have revealed and characterized the principal element of a concept of “economical safety of pharmaceutical organization” and the interconnection of these elements. As the result of this study, we have formed a conceptual model of the management of analyzed subsystem of pharmaceutical management.

Optimization of pharmaceutical support of patients with diabetes mellitus who have to use expensive drugs for the life term is particularly marked among the important problems for a healthcare of international society countries including the Russian Federation. Upon that, the consuming of antidiabetic drugs has its regional peculiarities which condition the need in conduction of studies of pharmaceutical support on a level of the certain region.

The timeliness of this subject is conditioned by the increase of a role of knowledge in pharmacy organizations (PO) management, significance increase of non-material assets in a competition on the pharmaceutical market. The development and substantiation of methodology of knowledge resources audit significance on the example of drug assortment formation for allergic rhinitis treatment. We have used sociological, statistic, expert methods of a study. Close attention was paid to the method of target management, construction of target tree. The construction of the target tree of the knowledge resources audit was based on the main target establishment, targets of the first level, and eight subtargets. We have offered new special positions of assortment formation. “Formation of consumers’ loyalty” is the target of the first level, subtargets “Analysis of clients preferences”, “Transformation of clients preferences”, “Positioning of consumers by the compliance degree”. We have determined the relevance significance by the main target achievement - rational assortment formation. We have shown that the achievement of the first level target “Formation of consumers’ loyalty” conduce the achievement of the main target by 40%. The analysis of the current assortment and a process of assortment upgrading guarantee the achievement of the target by 30% each. The methodology is prospective for knowledge resources audit by the knowledge resources evaluation, assortment formation, pharmacy organization.