Vol 17, No 3 (2017)

The aim of our work is theoretical substantiation of application of electroencephalographic method (EEG) in the evaluation of cognitive functions as indirect indicators of the adaptive homeostatic subsystem status and functional reserves of the individual. The review includes the application of EEG in the professional psychological selection, screening of the functional status and the study of cognitive functions among servicemen and specialists of the law enforcement agencies. We write about physiological mechanisms of functional status and cognitive functions in the norm, stress, pathology. We analyze studies of fractal, stochastic parameters of EEG. We propose to include EEG into cross-validation studies that will be included into the modern methodical apparatus of psychodiagnostics.

Research objective: The aim of this work was a comparative study of the contents of the Chlamydia pneumoniae and IL-8 in unstable and stable atherosclerotic lesions in humans,and an assessment of their role in the destabilization of atherosclerotic plaques. Materials and methods: Investigated 38 aortic tissue samples received from 63±7 years men who died from coronary heart disease. Verification of unstable progressive atherosclerotic plaques was conducted using histological staining Oil Red O and hematoxylin Mayer. Chlamydia pneumoniae to identify modified histological method Romanowski-Giemsa. Determination of IL-8 was made highly sensitive two-stage biotin-streptavidin method. Analysis of the results was carried out using a light microscope Leica DM 2500 and computer program «Leica Application Suite Version 3.4.0». Results: In surface divisions of unstable atherosclerotic lesions of human arterial walls identified Chlamydia pneumoniae, expressed cellular products of IL-8 and mononuclear cells infiltrates consisting of lymphocytes and macrophages. Conclusion: The results can indicate a combined mutually enhances action Chlamydia pneumoniae and IL-8 in the formation of unstable atherosclerotic lesions.

The research objective is comparison of psychoe motional state of patients suffering from disseminated sclerosis that were taking Enterococcus faecium L-3 and patients and that were not taking it. Research materials and methods. For evaluation of psychoe motional state of patients suffering from disse minated sclerosis two groups were created (control group and experimental group), each of the m amounted to 15 persons having definite diagnosis dissminated sclerosis. Standard questionnaires were used («Dominant condition» and «Actual condition» by L.V. Kulikov, questionnaire «Health,activ-ity,mood»,scale of situational (reactive) state anxiety by Ch.D. Spilberger and Yu.L. Khanin,and technique of differential diagnostics of depressive states by V. Zung). Results. After a course of probiotics intake indices at patients of experimental group (р<0.05) have been definitely improved in accordance withscales of the «Dominating state» questionnaire: «Relaxedness - potential stress» , «Evenness - psychic tension» , «Stability - instability of emotional background», «Satisfaction - dissatisfaction withlife in general» and in accordance withthe scale „Evenness - psychictension“ of the „Actual state“ questionnaire. Opinion. Obtained results bear evidence that the course intake of Enterococcus faecium L-3 has positive influence on psychoe motional state of patients having the diagnosis disse minated sclerosis.

Objective. Conducting systematic analysis of data on morphofunctional characteristics of the endometrium during the "window of implantation' : in normal and pathological conditions. Materials and methods. The analysis of 59 sources of literature in the electronic databases such as "PubMed", "eLIBRARY", "Doctor's Library' : was performed. Results. Problems of infertility and miscarriage do not lose their relevance and require new solutions. The morphofunctional state of the endometrium is important in the implantation process. Complex of structural and functional characteristics of the endometrium ensuring successful implantation is defined as endometrial receptivity. Endometrial receptivity is generally considered on three levels: genetic, proteomic and histological. In the process of implantation , various molecules are involved, providing a multifactorial "dialogue" : between the endometrium and the blastocyst. Such molecules include cytokines, adhesins, antiadhesins, growth factors, ion channels. The full binding of sex steroids with their receptors in the endometrium leads to its adequate phase transformation. Conclusion. The review presents current knowledge about the importance of molecular factors in the receptivity of the endometrium during implantation.

Aim of the study: Comparative analysis of the structure of non-infectious pathology in descendants of Mayak female workers which had accumulated preconceptional external gamma exposure. Material and methods: A retrospective study was carried out on the basis of the children register of Ozersk city. The structure of somatic pathology of 650 children under 15 years old, 130 of which were children of Mayak female workers was analyzed. Nonparametric statistics methods were applied. Results: The range of external gamma-irradiation doses on the ovaries in mothers of the main group was 0.09-3523.7 mGy; the average absorbed dose on the ovaries was 423.2 mGy. The predominance of respiratory diseases,skin and subcutaneous tissue diseases with a high percentage of allergodermathoses, diseases of digestive syste m with frequent occurrence of gastroduodenal pathology and diseases of hepatobiliary syste m were noted in the structure of the somatic pathology in descendants of irradiated mothers. A high frequency of polymorbidities in the study group was noted. Significant differences with the control were not found. Conclusion: Expansion of children cohort and gathering of new data will allow drawing final conclusions about the contribution of parental exposure to the development of multifactorial diseases in offspring.