Vol 53, No 1 (2004)

Original Research

Symptom of stress incontinence: pathogenesis, differential diagnosis and treatment problems

Aylamazian Е.К., Savitskiy G.A., Niaury D.А., Sednev О.V., Ziyatdinova G.М.


The symptom of stress incontinence can be the manifestation of the organic and functional pathology of the bladder and urethra. Consequently, there is necessity of the differential approach to the choice of treatment methods. In present article, the problem of stress incontinence is discussed according to pathophysiological point of view.

Journal of obstetrics and women's diseases. 2004;53(1):11-15
pages 11-15 views

The microbiological investigations in the diagnostics of infections affecting human reproduction

Savicheva A.М., Bashmakova М.A.


In the article there are data concerning the development of research activity in the field of reproductive tract infections fulfilled at the laboratory of microbiology, the D.O.Ott Research Institute of Obstetrics and Gynecology, for last one hundred years. The importance of microbiological investigations in diagnosing genital, perinatal and neonatal infections is underlined. Own data on diagnostics, epidemiology, clinical manifestations of listeriosis, toxoplasmosis, viral and bacterial infections are present in the article.

Journal of obstetrics and women's diseases. 2004;53(1):16-21
pages 16-21 views

Hemostasis system and immunomorphologic state of placenta under presence of antiphospholipid antibodies in plasma with consideration of their class and pregnancy outcome

Kosheleva N.G., Zubzhitskaia L.В., Arzhanova О.N., Tyshkevich О.V., Gromyko Y., Shlyakhtenko Т.N., Pluzhnikova Т.A., Shapovalova Е.А.


The present study was undertaken to investigate hemostasis system of 197 women with recurrent miscarriage: Analysis placentas by immunomorphology are studied of 41 women and of 52 women with autoimmune antibodies to β2-glycoprotein-I (β2-GPI) in placenta. There was exposed hyperactivation platelets blood of all women with antiphospholipid antibodies irrespective of groups with significantly was increased at the beginning of pregnancy and progressed with growing gestation. As result of investigation it is determined certain connection between outcome of pregnancy and activation degree platelets blood in vasculars. Was found absence influence anticardiolipin antibodies (aCL) on plasmocoagulative link hemostasis. The circulation of lupus anticoagulant (LA) was accompanied indication of hypercoagulation. In all research groups was determined significant oppression of fibrinolisis. Analysis placentas by immunomorphology was determined significantly tissue damages with LA and β2-GPI-dependent aCL.

Journal of obstetrics and women's diseases. 2004;53(1):22-26
pages 22-26 views

Development of the conception about universe hemodynamic reactions in the functional system: mother-placenta-fetus

Konstantinova N.N., Pavlova N.G.


In this article, one discusses the development of conceptions concerning the functional system mother—placenta—fetus and the pathogenic fnechanisms of hemodynamic reactions happening in it during pregnancy.

Journal of obstetrics and women's diseases. 2004;53(1):27-30
pages 27-30 views

From experiments with artificial insemination of rabbits to assisted reproductive technologies

Korsak V.S.


The contribution of the Ott institute collaborators in formation and development of auxiliary reproduction technologies is elucidated in this article.

Journal of obstetrics and women's diseases. 2004;53(1):31-36
pages 31-36 views

Etiо pathogenesis of spontaneous abortion

Arganova О.N., Kosheleva N.G.


One studied immunologic and genetic aspects of spontaneous abortion and the placenta insufficiency role in this pathology. It was determined, that increasing the production of cytokines by placenta's macrophages through something leads to increasing the reduced myometrium activity. Under cariotyping husbands and wives had spontaneous abortions on early terms it was found various genic and endocrine disturbtions. Modern topic diagnostics and algorithm of pregnancy observation with consideration of spontaneous abortion etiopathogenesis, treatment and placenta insufficiency prophylactics have permitted in most cases (more 93%) to give normal term of birth, to decrease perinatal losses.

Journal of obstetrics and women's diseases. 2004;53(1):37-41
pages 37-41 views

Disturbtion of the endosalpingeal ultra-structure as a sterility cause under distal uterine tube occlusion

Lyatoshinskaia Р.V., Kira E.F., Bezhenar V.F., Novozhylova А.Р.


We analyzed the ultra-structure of endosalpingian microbiopsies in 26 infertile patients with hydrosalpingites. We calculated the percentage of ciliated cells and estimated different parameters including the height of the epithelium, the presence of adhesions, epithelial desquamation, inflammatory cells and fibrosis in the wall. The microbiopsies were also investigated for their fine structure by transmission microscopy. Abnormalities of the kinocilia were detected. It was found that the formation of the hydrosalpingites is followed by the development of the deep dystrophic changes in endosalpinx. The latter can be the reason for the functional tubal disability in infertile patients.

Journal of obstetrics and women's diseases. 2004;53(1):42-48
pages 42-48 views

Risk factors for obstetric-gynecological pathology of pregnancy and childbirth, leading to perinatal losses

Nagaryan I.G., Kostyuchek D.F.


Unfavourable current gestation process is reflected in a level and structure of perinatal losses (PL). Prognostic risk factors of obstetric-gynaecological pathology of PL are revealed. Real pro-phylaxis of PL is based on diagnostics of subclinical infringements of pregnant condition and their preventive corrections.

Journal of obstetrics and women's diseases. 2004;53(1):49-54
pages 49-54 views


Certain historical, practical and scientific aspects of prenatal diagnostics in st. Petersburg

Baranov V.S.


Prenatal diagnosis (PD), as a relatively new area of ​​medical genetics, is experiencing a period of rapid growth. Methodological problems of PD associated with the selection of women at high risk of congenital and hereditary pathology, complex examination of the fetus using non-invasive (ultrasound) and invasive (cytogenetic, molecular, biochemical) research methods have already been resolved. Further increase in the effectiveness of PD, its scientific and practical significance depends entirely on the level of organization of this service in the field and its funding. An important role in the development of modern PD in Russia was played by the PD laboratory of the N.I. BEFORE. Otta RAMS.

Journal of obstetrics and women's diseases. 2004;53(1):82-88
pages 82-88 views

Reproduction immunology: old dogmas and new conceptions

Pavlov О.V., Selkov S.A.


The article reviews the recent data concerning the role, which components of immune system play in the regulation of gestation. The evidences are provided for the participation of cytokines and immune cells in pathogenesis of pre-eclampsia and spontaneous abortion. The attempt has been made to demonstrate the evolution of ideas and conceptions in this field for past 10-15 years.

Journal of obstetrics and women's diseases. 2004;53(1):89-97
pages 89-97 views

Role of bio-genic amines for the hypothalamic regulation of reproductive function

Arutiunian A.V., Kerkeshko G.О., Stepanov М.G., Korenevskiy А.V., Aylamazian Е.К.


  • The present review is dedicated to monoaminergic systems involved in hypothalamic regulation of reproduction, as well as to the role of the systems in GnRH synthesis and secretion regulation. Data are presented on the ovarian steroid hormones, the suprachiasmatic nuclei of the hypothalamus, in which the central oscillator of a mammalian organism's diurnal rhythms is located, and on the pineal hormone melatonin involved in formation of reproductive cycles. Both own results and literature data referring to the role of diurnal rhythms of the activity of monoaminergic systems of the hypothalamus in the central regulation of reproduction are discussed.
Journal of obstetrics and women's diseases. 2004;53(1):98-106
pages 98-106 views

Osteoprotegerin and its ligands for regulating the osteal resorption: experimental and clinical application aspects under estrogen deficiency conditions

Yureneva S.V.


Modem conceptions concerning the role of OPG-RANK-RANKL system in a local paracrinic mechanism of the regulation of osteoclastogenesis and osteal resorption processes are presented in this article. Here, results of the first clinical researches of prognostic signification of ORG determinations for estimating disruption manifestations in osteal metabolism under estrogen deficiency conditions as well as data on the OPG use as an anti-resorbable agent at the treatment of post-menopausal osteoporosis.

Journal of obstetrics and women's diseases. 2004;53(1):107-110
pages 107-110 views

Current public health problems

From the Imperial obstetrics institute to the first academic institute of obstetrics and gynecology in Russia

Aylamazian Е.К., Tsveliov Y.V.


This article is dedicated to the significant date in domestic obstetrics and gynecology history, to wit: 100 years from the day of building and opening the D.O. Ott Scientific and Research institute of obstetrics and gynecology of RAMS.

Journal of obstetrics and women's diseases. 2004;53(1):4-10
pages 4-10 views


Tromboembolic complications in obstetric- gynecological practices

Bezhenar V.F., Tsveliov Y.V., Kaplun I.В., Levshankov А.I., Shchiogolev А.V., Kandyba D.V., Savello А.V.


In clinical lecture, etiology, pathogenesis, principles of diagnostics and methods for treatment of tromboembolic complications, which the most often an obstetric- gynecologist meets in its practice. Authors present their own clinical observations, which allow to them formulating the main principles of tromboembolism prophylaxis in obstetrics and gynecology.

Journal of obstetrics and women's diseases. 2004;53(1):55-72
pages 55-72 views

Waves of gonadotropins and diagnostics of hormonal insufficiency of ovaries

Potin V.V.


The article describes an algorithm for diagnosing hormonal insufficiency of the ovaries, which helps to choose the best way to overcome hormonal infertility.

Journal of obstetrics and women's diseases. 2004;53(1):73-76
pages 73-76 views

Diagnostics and treatment of dysfunctional uterine bleeding in the perimenopause

Tarasova М.A., Yarmolinskaya М.I.


The reasons of dysfunctional menometrorrhagia in the perimenopause are revealed in the article , the algorithm of patient examination and necessity of differential diagnostics are given, methods of hormonal and surgical treatment of this disease are presented.

Journal of obstetrics and women's diseases. 2004;53(1):77-81
pages 77-81 views


Peculiarities of medical ethics in children’s gynecology

Balasanian V.G., Mikirtichan G.L.


The complex anonymus sociological inquiry of children's gynecologists, their patients and patient mothers was fulfilled. Questionnaires manifested that no all questioned physicians correctly understand and observe the principles of medical ethics and deontology concerning the medical secret, examination ethics, informed agree etc. This leads to conflicts among patients and their parents, to unsatisfactory of the received medical assistance. One gives references on the organizational-deontological aspect improvement for the children's gynecology service.

Journal of obstetrics and women's diseases. 2004;53(1):116-122
pages 116-122 views

Patient rights and physician responsibility - the lawyer view

Ballo A.М.


At present, it is well known that the number of claims against medical organizations of various organizational and legal forms of ownership is steadily growing. The amount paid to patients as reimbursement for inadequate medical care is also on the rise.

Journal of obstetrics and women's diseases. 2004;53(1):123-126
pages 123-126 views

Medical ethics, deontology and legislation at the obstetrician-gynecologist work

Aylamazian Е.К., Tsveliov Y.V.


Authors put series of concrete questions concerning medical ethics and deontology at the obstetrician-gynecologist work and propose to discuss them.

Journal of obstetrics and women's diseases. 2004;53(1):111-115
pages 111-115 views

History page

"On the decent institution of Babichiev's case in favor of society" (to the 250th anniversary of the decree of the ruling Senate)

Цвелев Y.V., Abashin V.G., Kalchenko А.Р.


April 29 (May 5) 1754 is a significant date in Russian obstetrics. On this day, the Governing Senate approved the representation of the Medical Chancellery (the highest body of state administration of medicine in Russia at that time) by issuing the Decree of Her Imperial Majesty Elizabeth Petrovna, which laid the foundation for the organization of obstetrics in Russia. The draft Decree was prepared by the President of the Medical Chancellery Pavel Zakharovich Kondoidi.

Journal of obstetrics and women's diseases. 2004;53(1):127-133
pages 127-133 views

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