Vol 24, No 4 (2016)

Aim. To define the clinically and practically significant differences in characteristics of women and men who suffer from alcohol dependency in terms of auto-aggressive behavior associated with alcohol dependence. The article presents the analysis of data obtained in 124 subjects divided into two groups 62 subjects each, women and men suffering from alcohol dependence.

Results. The study shows that women and men suffering from alcohol dependence have certain features throughout the course of the disease in the context of the auto-aggressive behavior. Most of the subjects were characterized by a hereditary development of the alcohol dependency represented by the presence of the alcoholism in mothers among 32% of female patients versus 10% among male ones. Women, in general, had more severe alcohol dependence (84% of the female subjects had rapid progression of the disease). The duration of therapeutic remission in most of the cases was less than a year, there were no prolonged therapeutic remissions (3 to 5 years).

Conclusion. Women and men have different course of the alcohol dependence, including the auto-aggressive behavioral characteristics, which in turn requires special attention of the medical services that provide narcological and anti-suicidal aid to both female and male patients. Development of gender-specific therapeutic approaches to the treatment of alcohol dependency is also required.

Objective. Assess the role of CT in patients with hepatic echinococcosis, and compare them with morphological changes.

Materials and methods. The study based on the results of examination and treatment of 18 patients with liver echinococcosis. All patients were performed CT examination on Neusoft 64 in the machine. Liver parenchymal density parameters evaluated in Hounsfield units in step of 1,5 to 5 mm, and the area determined by the liver cysts.

Results of the study. Mean cyst size (length, width, thickness) were 80,5 ± 6,7 (length), 64,4 ± 4,7 (width), 57,2 ± 3,6 (thickness) mm, respectively. The average liver area 20666,7±345,0, cyst area 20666,7 ± 345,0. The density of cysts on Hounsfield was -17,4± 4,7. Density of 0,5 cm from the liver tissue cysts 24,2 ± 5,7, liver tissue density of 1 cm from the cysts 24,9 ± 5,9, Liver tissue density of cysts 1,5 cm 45,6 ± 5,5, the density of the liver 2 cm from the tissue cysts 50,2 ± 6,1., the liver tissue density of 2,5 cm from the cysts 59,2 ± 7,1, the liver tissue density of 3 cm from the cysts 71,6 ± 8,2, a density of 4 cm from the liver tissue cysts 72,2 ± 8,4, the average density of the liver tissue to remove cysts from 5 cm to 8 cm 71,4 ± 8,2. When comparing the results of computer tomography (density tissue Hounsfield) were found that the changes in the liver tissue density from 24,2 ± 5,7 to 50,2 ± 6,1 HU observed at different distances expressed morphological changes of hydatid cysts: fi-brotic changes in the liver tissue, the presence of necrobiotic changes, inflammatory infiltration, degeneration of hepatocytes and hearths hemosiderosis 2-3 degrees. In this normal liver morphology data structure of the liver was areas where parameters of liver tissue density on CT matched normal parameters.

Conclusions. CT examination is highly informative in identifying liver disease and the presence of cyst volume of morphological changes in the liver.