Том 2, № 1 (2005)

Ultrastructural changes in the astrocytes of medullary gigantocellular reticular nuclei of growing rats under the effect of severe emotional-pain stress are studied. There are some differences in the manifestation of morphological reactions of neuroglial cell depending on its localization. Intracellular vacuolization, pericellular edema, but not safety mitochondrial ultrastructure evidence of prominent, and non-excessive changes are observed in growing astrocytes.

The aim of this study was to establish the most important structural changes of hepatic cells in liver cirrhosis, using morphometry of nuclei, nucleo-lar apparatus with systemic mathematical analysis. The material was taken from 95 autopsy cases. Data of quantitative analysis suggest high diagnostic value of karyometry and nucleolar organizer regions quantification for revealing the cause of liver cirrhosis.

The results of exaluation of toxicity of water-salt extracts of pathogenic burkholderies (B.pseudomallei, B.mallei) and non-pathogenic (B.thailandensis) variants in four types of cells: mice fibroblasts L-929, cells of Chinese hamster ovarial tumor, CHO KI-1, mice BALB/c macrophages and infusoria Paramecium caudatum were presented. It was shown that as for sensitivity method of defifnition of toxicity in infusoria is close to testing in cells CHO K-1 and L-929. Defining toxicity toses causing death of infusoria but not damaging them may be simple and accessible.

Principles of classification and evaluation of heart rythm regularity by Baevsky, were used to analyze the level of psychophysiological adaptation to stess. The optained data make possible to use the level values as a prognostic criterion for the personell of military structures, working in highy dangerous conditions.

Tolibut is a new analog - malate, oxalate, succinate nicotinate, citrate, glutamate tolibut and complex tolibut with glycin - in doses 10-15 mg/kg improves functional states in myocardial ischemia, particularly during 30 minutes occlusion of coronary artery. Tolibut and its salts - malate and citrate have a more marked antiischemic effect.

A comparative assessment of physical development of schoolage children (7-17) in Volgograd was undertaken on the basis of two investigations, carried out uniformly with an interval of 25 years. It was revealed that the growth processes in younger schoolchildren have stabilized. In most age and sex groups the body length of modern schoolchildren keeps increasing; the high rates of height and weight increase have been preserved. A decrease in chest circumference was revealed, especially in boys, as well as a decrease in strength, un the rate of muscle development and vital capacity of the lungs. For a more precise assessment of the dynamics of young people' s physical development at various points in time and in different age groups in a specific region, monitoring of physical development is considered to be indispensable.

The method of fixation of vaginal stump to the base of round uterine ligaments has been worked out. The method is performed as the final stage of panhysterectomy and prevents prolapse or complete inversion of vagina due to the formation of "frame" out of ligaments holding the vaginal stump.

The data on vasomotor reactivity of aa. humeri, intimomedial complex thickness of aa. carotis and pulse wave distribution rapidity in patients with diabetes mellitus 2 associated with hypertension or its lack (n = 48) are summarized in the study. In patients with diabetes mellitus 2 complicated by hypertension associated with limited dilatation after occlusion, nitrogenii oxydum (NO) action, intimomedial complex thickness increase in aa. carotis. Dilatation reserve exhaustion in patients with diabetes mellitus 2 and hypertension correlated with such BP monitoring parameters as night BP load, morning BP rise value and rapidity are investigated.

It is well known that cytomegalovirus (CMV) and herpes simplex virus (HSV) are the agents persisting in the human organism and causing different diseases. The results of examination of individual groups of population of the Volgograd region for the presence of cytomegalovirus and herpes virus infections have shown that the importance of this problem is still great at present. Percentage of the detection of specific antibodies (Ig G) in ratioto CMV was 35-72 % and in ratioto HSV-59-100 %. The rates of antibodies titres varied from 1:200 to 1:3200. It was demonstrated that the successful diagnostics of CMV and HSV infections must include comprehensive examination of patients with simultaneous determination of antibodies titres in blood serum and detection of virus or its antigens in mucosal scrapes, formed elements, urine.

The objective of this study was to research the peculiarities of stimulative and contractive ureteric activity in early postoperative patients with rectal cancer who had colocystoplasty. it was established that in such patients the bladder registered a regular high-amplitude electric activity of smooth muscles directed at preservation of contractive activity of the ureter and anterograde urinary tract. In the intestinal segment used for cystoplasty a drastic decrease in the specific weight of commissures potentials which indicates a lack of peristaltic waves in the urinary system and a decreased tone of the artificial blader.

The renessiance of anatomy began as early as XVth century. In the XVIth century it developed tremendously; two theatres for dissection were established, one in 1552 in Venice and the other in 1556 in Montpeilier, although in the latter university dissections had been made for years, for we know that Rabelais dissected there in 1532. Anatomical discoveries became numerous through the work of Junther of Undernach (1487-1574), Fallopius (1523-1562), Michael Servetus (1509-1553), Andreas Vesalius (1514-1564), Gaspar Bauhin (1560-1624), Berenger of Carpi (1480-1550), Andreas Caesalpinus (1524-1603), J.C. Arantius (1530-1589), Voicher Coiter (1534-1600), John Philip Ingrassias (1510-1580), Fabricius ab Aquapendente (1537-1619), Barthoiomeus Eustachius (1520-1574), and Realdus Columbus (1516-1559); in 1559 he described the pulmonary circulation.

The article deals with the reflection of mythical concepts in the folktale discourse. The evaluative component of the concept is viewed as a key element that may cause cognitive changes in the value and image constituents of the concept, which lead to the semantic restructuring of the concept in the text.

The problem of understanding of a person by another person arises not only on borders of cultures, but in conditions of belonging to different social groups, subcultures. Hermeneutis is engaged in solving this problem, as it developed the principles of interpretation and understanding the sources, that make possible polysemantic interpretation. The interpretation enables us to overcome ignorance of the world, while multiple interpretation, shifting the subject from one level of knowledge to another, forms ability to self-development, to perception of value-semantic sphere of another person. Communicative basis of interpretation of the value-semantic context is " the dialogical community " (L.V. Bukharaeva), that is understood as a practical dialogue being an encounter of multiversion positions, views, attitudes. Four stages of entering in interpretation are singled out: self-positioning of a subject in a dialogue; development of a contact, free from stereotypes of another person; a reflection and evolution of a personal position; a constructive value-semantic exchange.