Vol 14, No 3 (2017)

Articles

BIOPRINTING OF ORGANS AND TISSUES

Gorbatov R.O., Romanov A.D.

Abstract

An analytical study of bioprinting of organs and tissues is presented. The most frequently used materials for creating scaffolds have been described. Various bioprinting technologies have been compared. The technical characteristics of various bioprinters, which are most often used for producing organs and tissues, have been considered. Biofabrication is analyzed depending on the stage of the process and includes preprocessing, processing, postprocessing. The results of the practical implementation of biofabrication of artificial organs and tissues are presented.
Journal of Volgograd State Medical University. 2017;14(3):3-9
pages 3-9 views

ERECTILE DYSFUNCTION AFTER TRANSURETHRAL SURGERY FOR BENIGN PROSTATIC HYPERPLASIA

Kyzlasov P.S., Martov A.G., Popov S.V., Orlov I.N., Goncharov N.A., Grin E.A., Zabelin M.V.

Abstract

This article provides summarized and statistical data about the impact of transurethral surgery for benign hyperplasia of the prostate on erectile function. It analyzes etiopathogenesis, reviews the dynamics of fluctuations of the erectile function after transurethral interventions.
Journal of Volgograd State Medical University. 2017;14(3):10-15
pages 10-15 views

HEMOSTATIC DISORDERS IN PATIENTS WITH DIABETES MELLITUS

Poliantsev A.A., Frolov D.V., Linchenko D.V., Skobeldina T.A., Ovanenko V.S.

Abstract

Diabetes mellitus is characterized by a number of changes in the hemostatic system, causing an increased risk of thrombotic complications. It can be considered as a separate thrombophilic condition. The purpose of the review is to identify the relevant patterns in order to reduce the risk of vascular complications.
Journal of Volgograd State Medical University. 2017;14(3):16-22
pages 16-22 views

EXTRACTION-PHOTOMETRIC DETERMINATION OF PYRIDOSTIGMINE BROMIDE AS A METABOLITE IN MODEL MIXTURES

Aloykhina M.I., Nikitina T.N., Schormanov V.K.

Abstract

A procedure of extraction and photometric determination of a pyridostigmine bromide metabolite represented as ion pair of tropeoline 00 in model mixtures has been developed. The method makes it possible to identify 1-methyl-3-pyridone in model mixtures with ballast substances.
Journal of Volgograd State Medical University. 2017;14(3):23-25
pages 23-25 views

EFFECTS OF AROMA COMPOSITIONS ON THE FUNCTIONAL STATE OF UNIVERSITY FEMALE STUDENTS DIFFERING IN PHYSICAL TRAINING LEVELS

Aleshina L.I., Fedoseeva S.U., Schedrina E.V., Scherbakova T.G.

Abstract

The functional state of university female students differing in physical training levels and its optimization with the help of stimulating and relaxing aroma compositions have been studied. The method of correcting psychoemotional states, cognitive and motor functions of female students by means of cold inhalations of essential oils and their compositions has been recommended.
Journal of Volgograd State Medical University. 2017;14(3):26-28
pages 26-28 views

DEVELOPMENT AND VALIDATION OF THE TECHNIQUE FOR A «DISSOLUTION TEST» FOR GML-1, NEW ORIGINAL ANXIOLYTIC TABLETS

Gaevaya L.M., Grushevskaya L.N., Sergeeva M.S., Illarionov A.A., Denisenko E.N., Avdyunina N.I., Pyatin B.M., Prokofeva V.I., Yudina D.V.

Abstract

The technique for a «dissolution test» for the tablets of GML-1 has been developed. The developed technique has been validated according to the main validation characteristics. The results of the validation have confirmed the applicability of the technique for assessing the quality of GML-1 tablets.
Journal of Volgograd State Medical University. 2017;14(3):29-32
pages 29-32 views

STRUCTURE OF THE INTERNET ORDERS FOR PHARMACEUTICAL GOODS

Ganicheva L.M., Vyshemirskaya E.V.

Abstract

We have analyzed the orders of Internet users for pharmaceutical products in the retail sector of the Volgograd pharmaceutical market. We have identified the range, established trade preferences of the customers using the online order service.
Journal of Volgograd State Medical University. 2017;14(3):33-35
pages 33-35 views

PHYSICAL INTERPRETATION OF NEURON TRAINING IN FUZZY CLUSTERING NETWORKS WHEN USING MICROTOMOGRAPHY IN MEDICAL AND BIOLOGICAL RESEARCH

Gorbachev S.V., Bykhalov L.S., Gorbacheva N.N.

Abstract

The physical bases and interpretation of the procedure for training neurons in the fuzzy cellular neural networks of Kohonen have been investigated. Based on them, the method of automatic calibration of digital X-ray microtomographs has been described. This method involves neural-fuzzy segmentation of a distorted image into a finite number of clusters. The method is of great practical importance for the use of microtomography in biomedical research.
Journal of Volgograd State Medical University. 2017;14(3):36-40
pages 36-40 views

CONDITION OF HUMORAL IMMUNITY OF ORAL CAVITY IN CHILDREN WITH PSYCHONEUROLOGICAL DISORDERS

Gulenko O.V., Khagurova S.B.

Abstract

The studies of humoral immunity parameters in the oral fluid in children with dental pathologies accompanied by psychoneurological disorders point up the critical intensity of local immunity of the oral cavity in response to bacterial aggression associated with the development of local oxidative stress.
Journal of Volgograd State Medical University. 2017;14(3):41-44
pages 41-44 views

MOTIVATION TO LIVE A HEALTHY LIFESTYLE AND FORMATION OF NUTRITIONAL STATUS IN PREGNANT WOMEN

Danylina T.F., Mihalchenko D.V., Donika A.D., Denisenko L.N., Danylina E.V.

Abstract

Low motivation of pregnant women to live a healthy lifestyle and acquire adequate food preferences have been established. Over the half of the respondents (51,1 %) report about two daily meals, which are often replaced by snacks; 52,1 % of the survey participants have tea with pastry and bakery products; bread products mainly consumed in the evening predominate in the diet of 12,2 % of the respondents. We have found that the pregnant women have non-balanced diets, in which excessive consumption of total fats, simple carbohydrates with low energy value prevails, and there is a lack of macro- and microelements, including iron and calcium.
Journal of Volgograd State Medical University. 2017;14(3):45-47
pages 45-47 views

MORBIDITY, MORTALITY AND THE QUALITY OF MEDICAL CARE IN CARDIOLOGICAL AND GASTROENTEROLOGICAL DISEASES OF THE POPULATION OF THE VOLGOGRAD REGION IN 2013-2015

Dyachenko T.S., Ivanenko V.V., Gonik M.I., Kulichkin A.S.

Abstract

A comparative analysis of the indicators of the overall morbidity, mortality and natural increase in the population of the Russian Federation and the Volgograd region for 2012-2015 has been carried out. The results of the assessment of the quality of specialized gastroenterological and cardiological care in the profile departments of II and III level hospitals in the Volgograd region in 2013-2015 have been considered. The indicators of the quality of medical care in the gastroenterological and cardiological departments of the hospitals of the Volgograd region have been analyzed.
Journal of Volgograd State Medical University. 2017;14(3):48-51
pages 48-51 views

INFLUENCE OF ENVIRONMENTAL TECHNOGENIC FACTORS ON THE DEVELOPMENT OF DIGESTIVE DISEASES IN CHILDREN AND ADOLESCENTS

Kapranov S.V., Kapranova T.S.

Abstract

The impact of environmental technogenic factors on the development of digestive diseases in children and adolescents in an industrial region has been demonstrated. The authors have provided recommendations to prevent the negative influence of technogenic factors on digestive diseases in children and adolescents.
Journal of Volgograd State Medical University. 2017;14(3):52-55
pages 52-55 views

PERSISTENCE OF HUMAN PAPILLOMAVIRUS IN THE UTERINE CERVIX AND ALLELIC GENE POLYMORPHISM OF TOLL-LIKE RECEPTORS AND INTERFERON LAMBDA

Kiseleva T.S., Gumilevskaya O.P., Matohina U.B., Vakhaniya K.P.

Abstract

The inheritance of a specific combination of alleles of the genes of toll-like receptors and cytokines is believed to lead to effective immunity against the human papillomavirus; some combinations are associated with insufficient immunity and lead to persistence of the virus in the body The women were examined for the presence of DNA HPV 16 and 18 types by PCR. Depending on the persistence of the virus, the women were divided into two groups and a comparative study was conducted based on the findings of cytological diagnosis of cervical smears for the purpose of early diagnosis of dysplastic changes and molecular genetic analysis of polymorphisms of Toll-like receptor genes (TLR 9 (T-1237C and A2848G), TLR 3 Phe-412 Leu) and cytokine IL28 rs8099917 T> G.
Journal of Volgograd State Medical University. 2017;14(3):56-59
pages 56-59 views

INFLUENCE OF GPR119 RECEPTOR AGONIST ON INSULIN PRODUCTION AND INSULIN RESISTANCE IN INTACT RATS AND RATS WITH EXPERIMENTAL DIABETES MELLITUS

Kurkin D.V., Bakulin D.A., Volotova E.V., Tyurenkov I.N.

Abstract

Hypoglycemic action of ZB-16, a novel GPR119 receptor agonist, is incretin-mediated and involves increased secretion of insulin in response to a glucose load. The administration of ZB-16 reduces glucose tolerance and insulin resistance index in rats with type 2 diabetes mellitus.
Journal of Volgograd State Medical University. 2017;14(3):60-63
pages 60-63 views

ROLE OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN THE PATHOGENESIS OF ATOPIC DERMATITIS IN CHILDREN

Lebedenko A.A., Semernik O.E., Kislov E.O., Katysheva Y.I., Botsman E.A.

Abstract

The article presents the findings of the study of vascular endothelial growth factor in children suffering from atopic dermatitis. The changes in its concentration were analyzed depending on the degree of severity and duration of the disease, the extent of skin lesions and the severity of clinical manifestations.
Journal of Volgograd State Medical University. 2017;14(3):64-66
pages 64-66 views

PECULIARITIES OF RECOVERY INFLUENCE OF PICAMILONUM ON THE SYSTEM OF THE BLOOD CIRCULATION IN DISADAPTED SWIMMERS

Likhodeeva V.A., Spasov A.A., Mandrikov V.B., Isupov I.B.

Abstract

The features of the influence of picamilonum on the indices of systemic circulation of disadapted swimmers were studied. We have demonstrated that the pumping function of the heart in the control and the placebo groups was determined by the activity of the cardiac component and, to a lesser extent, by the vascular component. This is implicated in significant inverse relationships between TPR and pumping and inotropic functions of heart. In the swimmers taking picamilonum, the pumping function of the heart was maintained mainly by inotropic mechanisms. Total peripheral resistence, which was inversely correlated with the pumping function of the heart, cardiac output, myocardial contractility and left ventricular capacity substantially contribute to the maintenance of a constant level of systemic BP.
Journal of Volgograd State Medical University. 2017;14(3):67-70
pages 67-70 views

LOCAL WOUND HEALING AGENTS IN THE TREATMENT OF ORAL EROSIVE LESIONS IN PATIENTS WITH PEMPHIGUS VULGARIS

Maksimova E.M., Al Asfari Feras Mohammed Sami -., Mikhalchenko A.V.

Abstract

The article presents the results of a comparative assessment of different treatment options for labial and oral pemphigus vulgaris. All the patients were divided into 3 treatment groups. The results of the study confirmed the efficacy of the combination of ismigen with other ointments in treating pemphigus vulgaris.
Journal of Volgograd State Medical University. 2017;14(3):71-74
pages 71-74 views

ANALYSIS OF THE DYNAMICS OF CRITICAL PHOSPHENE FUSION FREQUENCY IN COMBINED TREATMENT OF GLAUCOMATOUS OPTICOPATHY

Piskun V.E., Vydrov A.S.

Abstract

The article analyzes the dynamics of critical phosphene fusion frequency in the combined treatment of glaucomatous opticopathy, including transcutaneous electrical stimulation of the optic nerve with ESOM apparatus and Semax 0.1%, an intranasal nootropic agent. The suggested method has proven its efficacy in the treatment of glaucomatous opticopathy.
Journal of Volgograd State Medical University. 2017;14(3):75-77
pages 75-77 views

DIFFERENT METHODS OF REVASCULARIZATION OF THE LOWER LIMB IN ORDER TO MAINTAIN SUPPORT ABILITY IN PATIENTS WITH NEUROISCHEMIC DIABETIC FOOT

Poliantsev A.A., Mozgovoy P.V., Frolov D.V., Linchenko D.V., Skobeldina T.A., Ovanenko V.S., Dyachkova Y.A.

Abstract

We attempted to improve the effects of short-term and long-term treatment of patients with neuroischemic diabetic foot. We conclude that X-ray and surgical interventions should be considered as the mainstream option for diabetes mellitus patients with critical lower limb ischemia.
Journal of Volgograd State Medical University. 2017;14(3):78-83
pages 78-83 views

SEARCHING FOR EFFECTIVE DRUG COMPOSITIONS TO TREAT EROSIVE AND ULCERATIVE ORAL LICHEN PLANUS

Poroyskiy S.V., Makedonova Y.A., Firsova I.V.

Abstract

We studied the clinical efficacy of the combination of tizol and L-arginine in treating erosive and ulcerative oral lichen planus and compared it with the standard treatment regimen. It has been shown that tizol and L-arginine produce the optimal concentration of the drug in the lesion and the optimal therapeutic effect. Tizol and L-arginine also potentiate each other's efficiency accelerate epithelialization and reduce the healing time of oral lichen planus lesions.
Journal of Volgograd State Medical University. 2017;14(3):84-88
pages 84-88 views

PHARMACOLOGICAL STUDY OF A SOFT MEDICINAL FORM CONTAINING NANOPARTICLES

Samkova I.A., Melnikova O.A., Larionov L.P., Petrov A.Y., Mordakina E.E.

Abstract

The article reviews the effects of complex soft medicinal forms containing nanoparticles on wound healing (IIIA and IIIB burns) in rats which were observed in an open field. We found that nanoparticle treatment can accelerate wound healing.
Journal of Volgograd State Medical University. 2017;14(3):89-92
pages 89-92 views

CLINICAL AND FUNCTIONAL OUTCOMES OF VARIOUS SURGICAL APPROACHES TO THE TREATMENT OF PROGRESSIVE KERATOKONUS

Solodkova E.G., Fokin V.P.

Abstract

The article analyzes the results of surgical treatment of progressive early and late-stage keratoconus using a femtosecond laser. Three groups of patients (n = 80, 80 eyes) were operated on for progressive stages I-III keratoconus. Based on the Amsler-Krumeich classification, corneal collagen cross-linking with excimer-laser-assisted deepithelialization is considered to be the treatment of choice for progressive keratoconus (stages I-II) with central cornel thickness due to its efficacy and stability. Corneal collagen crosslinking with a femtosecond-assisted intrastromal pocket for administration of a photosensitizer and local ultraviolet irradiation is considered to be the treatment of choice for progressive keratoconus (stages I-II) with peripheral corneal thickness. Intralamellar keratoplasty with corneal segment implantation can effectively arrest the progression of stage III keratoconus and improve visual acuity both in the short and long term through improving anterior and posterior corneal surface regularity. All cases showed a statistically significant increase in visual acuity (NCD and IHEC), a decrease in keratometric corneal parameters, and a decrease in anterior and posterior corneal elevation.
Journal of Volgograd State Medical University. 2017;14(3):93-97
pages 93-97 views

THE RELATIONSHIP BETWEEN PERIODONTAL DISEASE AND OBESITYACCOMPANIED BY HYPERTENSION

Starikova I.V., Piterskaya N.V., Radyshevskaya T.N.

Abstract

The study evaluates the prevalence and clinical features of periodontal disease in obese people with arterial hypertension. It has been reported that obese patients with hypertension and a high BMI have a higher prevalence of metabolic disturbances characterized by increased levels of basal and glucose-stimulated insulin. We found that patients with metabolic syndrome and grade III obesity are more likely to have chronic generalized severe periodontitis.
Journal of Volgograd State Medical University. 2017;14(3):98-101
pages 98-101 views

ANALYSIS OF THE RESULTS OF EARLY ORTHODONTIC TREATMENT IN CHILDREN WITH CONGENITAL BILATERAL CLEFT LIP AND PALATE WITH A REMOVABLE ORTHODONTIC APPLIANCE

Fomenko I.V., Vologina M.V., Kasatkina A.L., Timakov I.E.

Abstract

The article presents the results of early orthodontic treatment of children with congenital cleft lip and palate with a removable orthodontic appliance in primary dentition.
Journal of Volgograd State Medical University. 2017;14(3):102-104
pages 102-104 views

A METHOD FOR QUANTIFICATION OF PLASMA CONCENTRATIONS OF METHYLDOPA

Khokhlov A.L., Dzhurko Y.A., Kubes V., Shitov L.N., Yaichkov I.I., Shitova A.M.

Abstract

We developed a rapid and sensitive method for quantifying plasma concentrations of methyldopa using HPLC-MS/MS. The range of concentration measurements was 0,02-3,00 цд/ml. The method was applied for pharmacokinetic study of methyldopa tablet formulations.
Journal of Volgograd State Medical University. 2017;14(3):105-108
pages 105-108 views

11 -DESOXYMISOPROSTOL TABLETS: INVESTIGATION OF TABLET STABILITY

Yalkaev A.G., Kildiyarov F.K., Kataev V.A., Khalikov R.A., Fedotova A.A.

Abstract

We studied the effects of storage conditions on the stability of 11-desoxymisoprostol tablets. We have found that 11-desoxymisoprostol tablets can be stored at room temperature for up to 2 years.
Journal of Volgograd State Medical University. 2017;14(3):109-112
pages 109-112 views

THE INFLUENCE OF ALIMENTARY HYPOMAGNESAEMIA ON THE GENERAL CONDITION OF LACTATING FEMALE RATS AND POSTNATAL STATUS OF THEIR OFFSPRING

Spasov A.A., Bugaeva L.I., Lebedev S.A., Korzhova T.M., Getmanenko A.Y.

Abstract

The article describes the results of the effects of experimental hypomagnesaemia induced by the intake of a magnesium salt-deficient diet for two months on the general condition of lactating female rats and survival of their offspring. We found that magnesium deficiency leads to a deterioration of the general condition of the female rats and reduces their body mass during pregnancy and lactation. Observational studies of the offspring allowed us to identify an insufficient increase of body weight in rats born from mothers with hypomagnesaemia and high death rates in newborn rats within the first two months after birth.
Journal of Volgograd State Medical University. 2017;14(3):113-117
pages 113-117 views

DYNAMICS OF MORBIDITYAMONG VORONEZH STUDENTS IN TERMS OF HEALTH-PRESERVING TECHNOLOGIES

Rogachev A.A., Fertikova T.E.

Abstract

The article presents the results of an investigation and comparison of morbidity among Voronezh students between 2010 and 2015 and focuses on the application of modern health-preserving technologies. We studied the relationship between objective data on the morbidity among students and self-reported health assessment questionnaires.
Journal of Volgograd State Medical University. 2017;14(3):118-121
pages 118-121 views

DYNAMIC RESEARCH INTO THE INFLUENCE OF INTENSIVE ACADEMIC LOADS ON THE STATE OF HEALTH AND PHYSICAL DEVELOPMENT OF LYCEUM STUDENTS

Scherbakova T.G., Alyoshina L.I., Muzhichenko M.V., Novikova E.I.

Abstract

The article presents the results of a dynamic research into the influence of intensive academic loads on the state of health and physical development of the students of the Volgograd young men's pedagogical lyceum. We could identify lyceum students whose regular course load requires correction and further follow-up.
Journal of Volgograd State Medical University. 2017;14(3):122-124
pages 122-124 views

HETEROGENEITY OF PATIENTS WITH ACUTE CHOLECYSTITIS

Natroshvili I.G., Prudkov M.I., Savitskaya A.V.

Abstract

The article analyzes the data obtained from a retrospective multi-center research which had been carried out in 8 clinical settings located in 4 Russian cities. The article describes demographics of patients with acute cholecystitis, the timing of hospital admission and surgery, frequency of incidence of acute cholecystitis and choledocholithiasis.
Journal of Volgograd State Medical University. 2017;14(3):125-129
pages 125-129 views

PROBLEMS ASSOCIATED WITH PROVIDING DENTAL CARE TO CHILDREN IN THE VOLGOGRAD REGION

Panchenko M.L., Maslak E.E., Dyachenko T.S.

Abstract

The provision of dental services for children in the Volgograd region improved between 2011 and 2015 and made up 81,9 % for pediatric dentistry, 69.9% for orthodontics, and 31,1 % for dental surgery. Availability of all types of dental services for children was better in cities and towns than in rural areas.
Journal of Volgograd State Medical University. 2017;14(3):130-132
pages 130-132 views

EVALUATION OF PHYSICAL DEVELOPMENT OF THE OFFSPRING BORN FROM DAMS WHICH RECEIVED LADASTEN DURING LACTATION

Denisova T.D., Bugaeva L.I., Sherbakova N.M.

Abstract

Experiments on rats showed that intragastric administration of ladasten at a dose 30 mg/kg to lactating dams exerted positive effects on their general condition and attitude to their offspring. Observational studies of the offspring showed that rats born from dams which received ladasten during lactation gained more weight, developed more quickly, their motor and sensory functions as well as physical activity were enhanced and puberty was precocious.
Journal of Volgograd State Medical University. 2017;14(3):133-136
pages 133-136 views

UNIFIED STATE REGISTER OF THE POPULATION ATTACHED TO THE MEDICAL INSTITUTIONS PROVIDING AMBULATORY CARE: LEGAL ASPECTS, AIMS AND OBJECTIVES

Shkarin V.V., Berseneva E.A., Kurakov D.A., Savostina E.A.

Abstract

The unified state register of the population attached to medical institutions providing ambulatory care in general medicine makes it possible to create unified state personified registries of medical care. The unified state register of the population attached to medical institutions providing ambulatory care in general medicine should be considered as a component of the unified state health information system. Based on the unified state register of the personified registries of medical care the main directions of medical statistics development were outlined.
Journal of Volgograd State Medical University. 2017;14(3):137-140
pages 137-140 views

Pravila dlya avtorov

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Journal of Volgograd State Medical University. 2017;14(3):144-144
pages 144-144 views

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