Vol 14, No 3 (2017)

This article provides summarized and statistical data about the impact of transurethral surgery for benign hyperplasia of the prostate on erectile function. It analyzes etiopathogenesis, reviews the dynamics of fluctuations of the erectile function after transurethral interventions.

A procedure of extraction and photometric determination of a pyridostigmine bromide metabolite represented as ion pair of tropeoline 00 in model mixtures has been developed. The method makes it possible to identify 1-methyl-3-pyridone in model mixtures with ballast substances.

The technique for a «dissolution test» for the tablets of GML-1 has been developed. The developed technique has been validated according to the main validation characteristics. The results of the validation have confirmed the applicability of the technique for assessing the quality of GML-1 tablets.

The physical bases and interpretation of the procedure for training neurons in the fuzzy cellular neural networks of Kohonen have been investigated. Based on them, the method of automatic calibration of digital X-ray microtomographs has been described. This method involves neural-fuzzy segmentation of a distorted image into a finite number of clusters. The method is of great practical importance for the use of microtomography in biomedical research.

Low motivation of pregnant women to live a healthy lifestyle and acquire adequate food preferences have been established. Over the half of the respondents (51,1 %) report about two daily meals, which are often replaced by snacks; 52,1 % of the survey participants have tea with pastry and bakery products; bread products mainly consumed in the evening predominate in the diet of 12,2 % of the respondents. We have found that the pregnant women have non-balanced diets, in which excessive consumption of total fats, simple carbohydrates with low energy value prevails, and there is a lack of macro- and microelements, including iron and calcium.

The impact of environmental technogenic factors on the development of digestive diseases in children and adolescents in an industrial region has been demonstrated. The authors have provided recommendations to prevent the negative influence of technogenic factors on digestive diseases in children and adolescents.

Hypoglycemic action of ZB-16, a novel GPR119 receptor agonist, is incretin-mediated and involves increased secretion of insulin in response to a glucose load. The administration of ZB-16 reduces glucose tolerance and insulin resistance index in rats with type 2 diabetes mellitus.

The features of the influence of picamilonum on the indices of systemic circulation of disadapted swimmers were studied. We have demonstrated that the pumping function of the heart in the control and the placebo groups was determined by the activity of the cardiac component and, to a lesser extent, by the vascular component. This is implicated in significant inverse relationships between TPR and pumping and inotropic functions of heart. In the swimmers taking picamilonum, the pumping function of the heart was maintained mainly by inotropic mechanisms. Total peripheral resistence, which was inversely correlated with the pumping function of the heart, cardiac output, myocardial contractility and left ventricular capacity substantially contribute to the maintenance of a constant level of systemic BP.

The article analyzes the dynamics of critical phosphene fusion frequency in the combined treatment of glaucomatous opticopathy, including transcutaneous electrical stimulation of the optic nerve with ESOM apparatus and Semax 0.1%, an intranasal nootropic agent. The suggested method has proven its efficacy in the treatment of glaucomatous opticopathy.

We studied the clinical efficacy of the combination of tizol and L-arginine in treating erosive and ulcerative oral lichen planus and compared it with the standard treatment regimen. It has been shown that tizol and L-arginine produce the optimal concentration of the drug in the lesion and the optimal therapeutic effect. Tizol and L-arginine also potentiate each other's efficiency accelerate epithelialization and reduce the healing time of oral lichen planus lesions.

The article analyzes the results of surgical treatment of progressive early and late-stage keratoconus using a femtosecond laser. Three groups of patients (n = 80, 80 eyes) were operated on for progressive stages I-III keratoconus. Based on the Amsler-Krumeich classification, corneal collagen cross-linking with excimer-laser-assisted deepithelialization is considered to be the treatment of choice for progressive keratoconus (stages I-II) with central cornel thickness due to its efficacy and stability. Corneal collagen crosslinking with a femtosecond-assisted intrastromal pocket for administration of a photosensitizer and local ultraviolet irradiation is considered to be the treatment of choice for progressive keratoconus (stages I-II) with peripheral corneal thickness. Intralamellar keratoplasty with corneal segment implantation can effectively arrest the progression of stage III keratoconus and improve visual acuity both in the short and long term through improving anterior and posterior corneal surface regularity. All cases showed a statistically significant increase in visual acuity (NCD and IHEC), a decrease in keratometric corneal parameters, and a decrease in anterior and posterior corneal elevation.

The article presents the results of early orthodontic treatment of children with congenital cleft lip and palate with a removable orthodontic appliance in primary dentition.

We studied the effects of storage conditions on the stability of 11-desoxymisoprostol tablets. We have found that 11-desoxymisoprostol tablets can be stored at room temperature for up to 2 years.

The article presents the results of an investigation and comparison of morbidity among Voronezh students between 2010 and 2015 and focuses on the application of modern health-preserving technologies. We studied the relationship between objective data on the morbidity among students and self-reported health assessment questionnaires.

The article analyzes the data obtained from a retrospective multi-center research which had been carried out in 8 clinical settings located in 4 Russian cities. The article describes demographics of patients with acute cholecystitis, the timing of hospital admission and surgery, frequency of incidence of acute cholecystitis and choledocholithiasis.

Experiments on rats showed that intragastric administration of ladasten at a dose 30 mg/kg to lactating dams exerted positive effects on their general condition and attitude to their offspring. Observational studies of the offspring showed that rats born from dams which received ladasten during lactation gained more weight, developed more quickly, their motor and sensory functions as well as physical activity were enhanced and puberty was precocious.