Ophthalmology journal

Medical peer-reviewed journal of research and practice “Oftalmologiceskie vedomosti” is published quarterly since 2008. The journal is published under the aegis of the All-Russian Public Organization “Association of Ophthalmologists”.

Chief editor

Dmitriy V. Davydov M.D., Ph.D., professor.

 Main publications of the journal are focused on key issues of modern ophthalmology: etiology and pathogenesis, epidemiology, clinical picture features, up-to-date methods of diagnosis, prevention, and treatment of eye diseases and of those of its adnexa.

The journal publishes original articles, scientific reviews, lectures, clinical case descriptions (presented by Russian and foreign authors), and informs about past congresses and conferences in Russia.

The journal is oriented toward practicing ophthalmologists, including ophthalmic surgeons, scientific and teaching staff of medical higher educational institutions, physicians in ophthalmology training, as well as for specialists of allied health specialties.

The journal’s mission:

  1. To integrate research results of Russian scientists and the rich clinical experience of practicing doctors in diagnosis, prevention, and treatment of eye diseases into the international scientific space; to be an international scientific platform for discussions and sharing experiences;
  2. To provide for ophthalmologists of the Russian Federation actual and high quality research and practice insights into most up-to-date treatment and prevention methods of eye diseases and of those of its adnexa.

Indexation

“Oftalmologiceskie vedomosti” journal is included into the List of peer-reviewed scientific journals and reviews, in which main research results of theses for a doctor's and candidate’s degree ought to be published.

The journal is indexing in the following international databases and directory editions:

  • RSCI
  • DOAJ
  • Google Scholar
  • Ulrich's Periodicals Directory
  • WorldCat
  • CNKI

The journal is registered by the Russian State Committee for Press and Mass Media on May 04, 2016 (Registration Number ПИ № ФС 77-65574).

 

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Current Issue

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Vol 13, No 3 (2020)

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Original researches
The main prognostic factors influencing the results of the superior tarsal muscle resection in patients with blepharoptosis
Goltsman E.V., Potemkin V.V., Davydov D.V.
Abstract

Transconjunctival methods of ptosis correction gain popularity nowadays. The wide use of the technique is limited because of the lack of clear recommendations regarding the volume of the resection, especially in patients with negative phenylephrine test.

Purpose. To assess the influence of main predictive factors on superior tarsal muscle (STM) resection result.

Materials and methods. Patients were divided into two groups according to the result of phenylephrine test (PE). Patients with positive results were included in the first group, with negative and weak results – in the second group. All patients underwent STM resection according our new algorithm.

Results. The result of STM resection was influenced by PE test and intraoperative white line motility test (WLM), but not by levator function and the amount of superior tarsal muscle resection.

Conclusions. PE and WLM tests play main role in choosing a method for blepharoptosis correcting.

Ophthalmology journal. 2020;13(3):7-12
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Optical coherence tomography of pseudophakic eyes after primary posterior capsulorhexis in pseudoexfoliation syndrome
Egorova E.V., Dulidova V.V., Chernykh V.V.
Abstract

Purpose to study vitreolenticular interface (VLI) and central retinal thickness after primary posterior capsulorhexis (PPC) in pseudoexfoliation syndrome (PEX).

Material and methods. We conducted a dynamic OCT-evaluation of the macular morphology (47 cases) and of the VLI (39 cases) in patients with PEX in early and long term period after uncomplicated cataract surgery with PPC. In the long term period a comparative OCT-evaluation of the macula was performed in 129 patients with PEX (159 eyes) in different groups: after phacoemulsification with and without PPC, after Nd:YAG laser capsulotomy for secondary cataract, and in the control group of non-operated eyes.

Results. The OCT-evaluation made it possible to visualize two significant features of VLI after PPC – intact anterior hyaloid and restoration of the capsule barrier. It took 3–8 days for full adhesion. Secondary cataract in the PPC area was detected in one case in the long-term period. Dynamic OCT-evaluation of the macula in the main group revealed a statistically unreliable increase in the macular thickness (3.4%) in post-op period at 1–3 months with subsequent regression. Such changes were within the limits of physiological norm. In the remote period, comparative OCT-evaluation of the macula in different groups did not reveal statistically significant differences with the control group.

Conclusion. OCT-evaluation at different post-op terms revealed the formation of stable vitreolenticular relationships and absence of clinically significant macular edema. Secondary cataract in the PPC area was detected only in one case.

Ophthalmology journal. 2020;13(3):13-19
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Cases of intraocular lens opacification in pseudophakic eyes: analysis of the results of microstructural studies
Riks I.A., Astakhov S.Y., Ivankova E.М., Kuzmina I.E., Papanyan S.S., Boutaba R., Ezugbaya M.B., Akopov E.L.
Abstract

Relevance. Currently, all over the world, during cataract surgeries, a huge number of intraocular lenses (IOLs) made of different materials are implanted. Alongside with the development of modern IOL materials and designs, publications about their opacities appear. The nature and the localization of IOL opacities mainly depend on the properties of the material out of which the lens is made. Polymethyl methacrylate (PMMA) currently rarely used to manufacture IOLs, tends to cloud in the optical center due to structural breakdown, forming “snowflake”-like cracks. Opacities of acrylic IOLs depend on the degree of hydrophilic properties of the material. The deposition of crystalline deposits in the optical zone of hydrophilic acrylic lenses leads to a significant decrease in visual acuity and requires IOL explantation. There is a definite dependence of the occurrence of opacities in hydrophilic acryl on the patient’s concomitant diseases. In hydrophobic acrylic IOLs, vacuoles form, and glistenings occurs. Herewith, visual functions, as a rule, do not suffer.

Purpose: to find out what structural changes in the IOL led to the need to remove them from pseudophakic eyes due to a decrease in visual acuity.

Materials and methods. Four clouded IOLs made from different materials were examined. The lenses were studied using a SUPRA 55VP scanning electron microscope (Carl Zeiss, Germany) using a secondary electron detector. Element distribution maps on the surface and inside the lenses were collected using an X-max 80 mm2 energy dispersive X-ray analysis detector (Oxford Instruments, UK).

Results. A hydrophilic lens with hydrophobic coating became cloudy 5 years after implantation. Hydroxyapatite crystals were found on all parts of the IOL along its surface. In a hydrophobic acrylic IOL, microvacuoles and cavities in the optical center were found using scanning electron microscopy. Two PMMA IOLs underwent self-destruction within 8 years after implantation. Chemical analysis of PMMA lenses did not reveal any inorganic compounds.

Conclusion. One of the complications of IOL implantation is an impairment of their transparency. Factors associated with IOL material and manufacturing, as well as the patient’s comorbidities, can lead to lens opacification at various terms after surgery.

Ophthalmology journal. 2020;13(3):21-28
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Comparative evaluation of the results of surgical treatment of open-angle glaucoma using an Ex-Press® P-200 filtration device and drainage device “anti-glaucoma implant A3”
Grineva M.K., Astakhov S.Y., Turgel V.A.
Abstract

Purpose. The article presents the results of a comparative analysis of the effectiveness of surgical treatment of open-angle glaucoma using the Ex-Press® P-200 filtering device and the “Anti-glaucoma A3 implant”.

Materials and methods. Using simple sequential sampling, 52 patients (59 eyes) were divided into 2 groups. The first group was implanted with Ex-Press® P-200, the second – with “Anti-glaucoma implant A3”. The follow-up period for patients ranged from 6 months to three years. At each visit, a standard ophthalmic examination was performed. For tonometry, the ICare TA01i portable non-contact tonometer was used. To assess the stabilization of the glaucoma process, we performed static (threshold) automatic perimetry using the Pericom perimeter and optical coherence tomography (OCT) of the optic nerve heads using a Spectralis HRA-OCT tomograph (Heidelberg Engineering).

Conclusions. The implantation of devices of both types led to a persistent decrease in intraocular pressure, maintenance of visual functions, and stabilization of the glaucoma process. Intra- and postoperative complications corresponded to the nature of filtering procedures and did not have significant differences in the groups. However, cases of shunt erosion were noted only in the group with implanted Ex-Press® devices.

Ophthalmology journal. 2020;13(3):29-36
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Interdisciplinary aspects
Comparison of results and quality of life in patients with thyroid eye disease after different methods of orbital decompression
Zhu W., Katinas E.B., Solovyov M.M., Fedotova K., Yaremenko A.I., Chachanidze E.V., Potеmkin V.V.
Abstract

Purpose. To evaluate the changes in the quality of life of patients with thyroid eye disease after different methods of orbital decompression.

Materials and methods. The study included 24 patients (37 orbits) with thyroid eye disease, aged 41.6 ± 20.6 (from 20 to 79 years), 18 women and 6 men. The patients were divided into two groups. The first group included 12 patients (19 orbits) who underwent orbital fat decompression. The second group included 12 patients (18 orbits) who underwent endoscopic endonasal bony orbital decompression. The Graves’ ophthalmopathy quality of life questionnaire (GO-QOL) was completed before surgery, and 3 and 6 months after it. Outcome analysis included also the assessment of visual acuity, proptosis, eyelid retraction, and palpebral fissure height.

Results. The GO-QOL visual function scores in both groups did not change significantly in 3 and in 6 months after orbital decompression (p > 0.05): in the first group, before and after 6 months, scores were 69.27 ± 20.02 and 68.96 ± 18.44, in the second group – 53.13 ± 29.13 and 57.81 ± 23.56, respectively. An improvement in the GO-QOL visual function estimation was observed in those patients whose visual acuity improved after surgery. The GO-QOL facial appearance scores significantly improved 3 months after surgery, and continued to increase up to 6 months: in the first group, facial appearance scores improved from 23.96 ± 23.01 to 48.42 ± 25.56 (p = 0.004), in the second group — from 47.92 ± 21.04 to 66.15 ± 23.15 (p = 0.037).

Conclusions. Orbital decompression significantly improves the quality of life of patients with thyroid eye disease, this is primarily associated with an improvement in facial appearance.

Ophthalmology journal. 2020;13(3):37-45
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Organization of ophthalmic care
Optical reconstructive surgery of the anterior segment of the eye in the far eastern federal district – achievements and unsolved problems
Kolenko O.V., Dyachenko Y.N., Sorokin E.L., Pshenichnov M.V.
Abstract

The aim was to analyze organizational and technical difficulties in introducing modern technologies of optical reconstructive surgery, and to find the options of their elimination.

Materials and methods. Organizational arrangements to develop and to introduce into clinical practice modern technologies of optical reconstructive surgery in treatment of corneal opacities of different origin in the Khabarovsk branch of the S. Fedorov Eye Microsurgery Federal State Institution of the Ministry of Health of the Russian Federation has been analyzed.

Results and conclusions. An unified register of patients of the Far Eastern Federal district who need optical keratoplasty (bullous keratopathies, keratoconus stages 3–4, post-traumatic leukomas, hereditary corneal dystrophies) – a waiting list – has been created. The necessary equipment and instruments were acquired, 4 surgeons were trained who mastered the technologies of deep anterior lamellar keratoplasty and Descemet membrane transplantation along with penetrating keratoplasty. From 2014 to 2018, 160 optical keratoplasty were performed using donor material; by 2019, the need for this type of high-tech treatment has been reduced by 2 times. To date, more than 30% of optical keratoplasties are performed using lamellar technology. The organizational sequence of ordering biological material, performing surgeries; the postoperative care system is got up and running; the outpatient departments’ophthalmologists of the region are trained to use clear objective criteria for dynamic follow-up of these patients.

Ophthalmology journal. 2020;13(3):47-54
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Experimental trials
Development and evaluation of the effectiveness of photodynamic therapy in inflammatory diseases of the ocular surface
Narzikulova K.I., Bakhritdinova F.A., Mirrakhimova S.S., Oralov B.A.
Abstract

Relevance. In the treatment of inflammatory diseases of the ocular surface, in order to achieve high efficiency in the shortest possible time, it is necessary for the therapy to be comprehensive. Today, in addition to traditional treatment methods, new technologies based on the use of low-energy lasers, which have high biological activity, are spreading.

Aim. To improve the treatment results of the inflammatory diseases of the ocular surface by implementing photodynamic therapy (PDT) in experiment and clinic, using domestic equipment and elaborating optimal energetic parameters of laser irradiation.

Methods. Objects of research: 130 nonlinear sexually mature rats weighing 150 grams contained in standard vivarium conditions and 110 eyes of patients with inflammatory eye diseases. Carrying out the investigation, experiments on animals, clinical and functional examination results of patients, and statistical analysis were taken into consideration.

Results. A methodology for complex treatment of inflammatory diseases of the ocular surface was developed (with inclusion of PDT by the laser therapy device “Vostok”), based on experimental data and confirmed by clinical and functional ocular indices. PDT helps to increase the effectiveness of treatment, which is manifested by accelerated tissue regeneration, restoration of corneal transparency, increase of visual function in 86.7%, and reduction of treatment terms to 6 days.

Conclusions. Anti-inflammatory and regenerative effectiveness of the proposed complex treatment of inflammatory diseases of the ocular surface with the PDT use was established: improvement in the clinical picture of conjunctivitis and keratitis was revealed, manifested by increase in corneal epithelization.

Ophthalmology journal. 2020;13(3):55-65
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Reviews
Telemedicine in ophthalmology. Part 2. “special teleophthalmology”
Astakhov Y.S., Turgel V.A.
Abstract

In recent years, telemedicine (TM) has been gradually introduced into ophthalmology in the form of teleophthalmology (TO), because most of the eye diseases can be photographed and transmitted via Internet. The most wide development of TO has involved the field of diabetic retinopathy (DR) diagnosis, primarily due to the high prevalence of diabetes mellitus in the world. Examples of the well-established operation of remote DR screening centers exist in different countries of the world. There are many studies published, which compare a remote examination with a personal one, and according to their data, TO screening is no worse, than traditional screening. In addition to DR, TO also covers the diagnosis of glaucoma, age-related macular degeneration, and other ophthalmic conditions. In this article, we present an overview of modern TO centers in different countries, the features of their organization and global results that have been achieved during their existence. New technologies developed to facilitate the work of such centers will also be touched: image analysis algorithms, portable diagnostic equipment, medical information systems. The prospects for introducing TO into Russian medical practice are considered separately.

Ophthalmology journal. 2020;13(3):67-80
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In ophthalmology practitioners
First results of endonasal balloon dacryoplasty use in recurrence after dacryocystorhinostomy
At’kova E.L., Krakhovetskiy N.N., Zhukov O.V.
Abstract

Background. In recurrent dacryocystitis after dacryocystorhinostomy, a re-operation is indicated. In recent years, some publications appeared concerning endonasal dacryoplasty using 9 mm-balloon in treatment of patients with recurrent dacryocystitis.

Purpose – to evaluate the possibility of using endonasal balloon dacryoplasty in recurrence after dacryocystorhinostomy.

Materials and methods. Into the study, 6 patients (6 cases) were included who underwent endonasal endoscopic dacryocystorhinostomy for dacryocystitis 1-3 years before. In all patients, evaluation of Munk’s scores for epiphora, optical coherence tomography (OCT) based lacrimal meniscometry, dye disappearance test, lacrimal drainage system syringing and probing of its horizontal part, nasal endoscopy, multispiral computed tomography of lacrimal drainage system with contrast enhancement. In all patients, endonasal dacryoplasty using a balloon with 6 mm diameter was carried out. The follow-up period after surgery was 6 months.

Results. In 4 patients, “recovery” was achieved, in 1 patient “improvement“ was obtained, in 1 patient there was dacryostoma cicatrization.

Conclusion. Preliminary results received in this study of the balloon dacryoplasty performed in 6 patients afford ground to consider it possible to use this method in patients with dacryocystitis recurrence after dacryocystorhinostomy. The matter of the prospects when using this method may be solved after further research aimed to increase the number of clinical observations to enhance the possibility of adequate statistical processing of obtained results, to extend the postoperative follow-up period, to develop the indications for this procedure, and to investigate the necessity in additional manipulations improving the effectiveness of endonasal balloon dacryoplasty.

Ophthalmology journal. 2020;13(3):81-86
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Case reports
Corneal collagen cross-linking in mixed etiology keratitis treatment: a case of successful use
Khripun K.V., Kobinets Y.V., Danilov P.A., Rozhdestvenskaya E.S., Nizametdinova Y.S.
Abstract

Acanthamoeba keratitis with bacterial, fungal superinfection or without it leads to development of an aggressive and long-standing corneal inflammation; up to now, the efficacy of its treatment stays doubtful and demands further investigation. For a long time, there were discussions on the possibility and expediency of corneal collagen cross-linking (PACK-CXL – photo activated chromophore for keratitis) in patients with bacterial, fungal and Acanthamoeba keratitis. This article presents a clinical case of effective treatment of mixed etiology keratitis by multiple high fluence accelerated PACK-CXL in a patient with severe local toxico-allergic reaction.

Ophthalmology journal. 2020;13(3):87-96
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Autotranslocation of the pigment epithelium-choroid complex in treatment of age-related macular degeneration scarring stage
Sosnovskii S.V., Boiko E.V., Oskanov D.K.
Abstract

The “gold standard” of the neovascular age-related macular degeneration treatment is the intravitreal administration of angiogenesis inhibitors. In subretinal macular fibrosis, antiangiogenic therapy is not effective. In such cases, subretinal surgery is used, in particular, autotranslocation of pigment epithelium-choroid complex. This paper presents a case of successful use of this method in a 77 y.o. female patient with subretinal fibrosis in the macular area as an outcome of neovascular age-related macular degeneration. An original method of translocation of “pedicled” pigment epithelium-choroid complex from the paramacular area to the macula was used. In 24 months, the visual acuity increased from 0.01 to 0.07; the central fixation was restored; the absolute positive central scotoma disappeared. During all the post-operative follow-up period, the full-rate pigment epithelium-choroid perfusion in the choroid of the translocated flap, the loss of choroidal neovascularization activity signs and of indications for intravitreal administration of angiogenesis inhibitors were proved.

Ophthalmology journal. 2020;13(3):97-104
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Anniversary
Alevtina Fedorovna Brovkina. My life motto is "Let's break through!"
 
Abstract

The article is dedicated to the 90th Anniversary, which was celebrated on June 30, 2020, an outstanding Soviet and Russian ophthalmologist, founder of the Russian ophthalmic and oncological school, Honored Scientist of the Russian Federation (1991), Academician of the Russian Academy of Sciences (2013), Professor of the Department of Ophthalmology with a course of pediatric ophthalmology and orbital pathology of the Russian Medical Academy of Postgraduate Education Brovkina Alevtina Fedorovna. It examines her life path: clinical, scientific and pedagogical activities and achievements.

Ophthalmology journal. 2020;13(3):105-106
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Reports
Report on the work of the XXVI International Ophthalmological Congress "White Nights" - the 16th Congress of the All-Russian public organization "Association of Ophthalmologists"
 
Abstract

Report on the work of the XXVI International Ophthalmological Congress "White Nights" - the 16th Congress of the All-Russian public organization "Association of Ophthalmologists"

Ophthalmology journal. 2020;13(3):107-108
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