Vol XXX, No 3-4 (1998)

There was performed investigation of rhelogic properties, of coagulation and anticoagulation blood systems in 88 patients of senile age with ischemic insult in the carotid system. It was determined that for elderly patients highly expressed tendencies for hyperaggregation and suppression of their own fibrinolytic blood activity are characteristic features. Initially increased level of aggregation and hypercoagulation, combined with presence in blood fibrin-monomer complexes were accompanied by progressing DIC syndrome, and as a rule, were associated with steady neurology deficiency and high incidence of mortality. Possible correction ways were considered for hemostasis system disorders in elderly patients.

On the basis of analyzing clinical data and data from past history of patients with postinsult neurologic dificiency, a conclusion has been made by correlation analysis and determination of connection closeness between separate clinical signs. The conclusion tells about nonhomogeneity of motor disorders genesis in patients with hemi-sphere insult, foundation of which different chains of pathophysiology process make up.

Study of biorhythmostimulation efficiency in complex treatment of patients with initial forms of brain blood supply insufficiency was carried out. The obtained results are indicative of high efficiency of the given method of psychoemotional condition of patients. True reliable normalisation of arterial pressure, brain vascular tension, vegetative nervous system, cerebral cortex electrical activity took place. Biorhythmostimulatuion is a highly effective and pathogenically substantiated method of psychoemotional condition correction and can be widely used with medical purposes for patients with initial forms of brain blood supply insufficiency.

Phosphoinositides in lymphocytes and machrophages in 20 patients with multiple sclerosis have been studied with the help of highly effective liquid and thin-layer chromatography. In all patients phosphoinositide metabolism inpairment was revealed, which can be caused both by impairment of phosphoinositide response of immunocompetent cells, and by connecting myelin with consequent demyelinization. The revealed fact may serve one of criteria of demyelinizathion process activity, and also evidences the certain role of the revealed impairment in multiple sclerosis pathogenesis.

Hemodynamics of children with natal trauma of spinal cord’s cervical department was studied. It was determined, that among numerous manifestations of late complications of natal cervical traumas amyotrophy syndrome of shoulder girdle is widely spread, in which in 65% of cases hemodynamics insufficiency is determined in the carotid region, and in 37% - in vertebro-basilar region. Functional tests allowed to determine occult blood flow insufficiency in vertebro-basilar region in 80% of cases, thus confirming presence of chronic circulatory insufficiency in the system of vertebral arteries in patients with amyotrophy syndrome of shoulder girdle.

Peculiarities of infringement of the vegetative status in children, having had concussion of a head brain are revealed. Infringements of vegetative systems’ activity was displayed by an oppression of eigotrop’s link, causing unsufficient vegetative reaction and inadequate vegetative maintenance of activity. Interrelation of character of vegetative reaction with terms of remote period was shown. Influence of age of the children, character of perynatal anamnes, degree of clinical indemnification were revealed.

The problem of rehabilitation of stroke patients is being actively developed in modern medicine. According to the World Health Organization, 100-300 cases of stroke occur annually in developed countries for every 100 thousand people. In Russia, these numbers are 250-320 among the urban population (according to the registers of cerebral stroke in Moscow and Novosibirsk) and 170 among the rural population (according to the Stavropol Territory).

Vascular diseases of the brain are widespread and largely determine such indicators of public health as life expectancy, morbidity, and mortality. In the overall structure of mortality, cerebral strokes rank second after heart disease.

According to WHO statistics, from 40 to 80% of the world's adult population suffer from clinical syndromes of osteochondrosis of the spine. As one of the most common causes of temporary disability, they lead to significant economic losses.

Since the discovery of the functional asymmetry of the cerebral hemispheres, interhemispheric lateralization and intrahemispheric organization of the brain have been a leading problem in clinical neurology.

The scientific and social activities of the talented neuropathologist Alexander Alexandrovich Kornilov have not received due reflection in the neurological literature, monographs and articles on the history of Russian neurology.