Vol 11, No 2 (2014)

Methods of treating large and giant ventral hernias and their complications are constantly updated as they are aimed at reducing the number of postoperative complications, recurrences and death. The article presents a review of foreign and domestic literature sources on the treatment of large and giant postoperative hernias in modern herniology.

We studied the influence of technological factors on the extraction of flavonoids from Conyza canadensis herb. Through experimenting we determined the conditions which ensure the maximum flavonoid fractional yield from Conyza canadensis herb (1,91 ± 0,003 %): grinding size - 1 mm, boiling time - 30 minutes, extractant - 70% ethyl alcohol, ratio of raw material and extractive solvent - 1:60, single extraction.

We revealed pathological changes in the lungs of patients who died from tuberculosis and HIV infection considering the immunological stage of the process. The structural changes were multidirectional and with CD 4+ > 200 cells/mcl (mediana is 356,2 cells/mcl) they were more similar to the pathomorphology of pulmonary tuberculosis without HIV-infection with limited foci of inflammation. As the secondary immunodeficiency progressed the number of CD 4 + ranged from 200 to 100 cells/mcl (mediana is 148,4 cells/mcl), clinical and morphological forms of pulmonary tuberculosis with destructive component prevailed and there was a tendency to generalization and inflammatory changes with exudative component. At the terminal stage CD 4+ lymphocyte count was less than100 cells/mcl (mediana is 49,4 cells/mcl), generalized forms of 2-sides milliary tuberculosis as well as alterative reactions in lung parenchyma and massive vasculitis in the microvasculature prevailed.

Intestinal insufficiencysyndrome (SII) is associated with acute pancreatitis in 18-80 % of cases and an increase in the permeability of the intestinal wall barriers induces systemic endotoxemia.

We analyzed clinical efficacy of immunotropic therapy based on bacterial lysates (IRS® 19) and ultra-low doses of affinity purified antibodies against human γ-interferon (Anaferon). We developed an algorithm of immunotropic therapy considering the positive effect on the major clinical signs and the course of the disease as well as immunological indicators.

The article analyzes the causes of hospitalization among children during the first year of life to nephrology department of the Volgograd children's hospital №8. The article highlights a significant increase in the number of hospitalizations for treatment goals and for the purpose of clarifying the diagnosis.

Comparison of anterior chamber IOL versus scleral IOL with suture fixation revealed similar effectiveness of functional findings for the correction of aphakia in cases of capsular support deficiency

Results of travatan test in 39 patients (39 eyes) with normal pressure glaucoma were analyzed. Evaluation of tolerant pressure was based upon findings of optical coherent tomography and static perimetry. The studies confirmed effectiveness of travatan test in diagnostics of normal pressure glaucoma.

A comparative analysis of ABPM indicators of LBW preterm newborns was conducted in the late neonatal period. The influence of maternal arterial hypertension durung pregnancy on the development of the circadian blood pressure profile in newborns was determined .

The study revealed equal efficiency of pancreatic graft autotransplantation involving venous drainage from the graft to the portal vein or to the systemic bloodstream in compensating carbohydrate metabolism after a pancreatectomy.

The findings of histological examination of mice liver in subacute CCL 4 liver injury in mice involved in srenous exercise revealed reliable hepatoprotective properties of ginseng and eleuterococcus correlating with those of the comparison drug of karsil.

Children with chronic pyelonephritis were examined. According to the findings in 54% of cases of chronic pyelonephritis the signs of impaired T- cell immunity were revealed, which was proved by the standard immunogram. We also found that despite the absence of clinical manifestations of disease, a latent inflammatory process in kidneys persists.

The reasons for the use of meldonium in treating type 2 diabetes mellitus accompanied by cardiovascular peripheral and autonomic neuropathy are stated in the present article.

A comparative analysis of morbidity patterns in sportsmen and individuals involved in sports activities in the Volgograd region was carried out between 2010 and 2013. Morbidity findings and data on the distribution of different nosological forms of diseases are presented in the article.

The ultrasound findings were retrospectively evaluated in 38 fetuses with the right aortic arch (RAA) diagnosed at 16- 34 weeks of gestation. The ultrasound examination revealed that all 38 fetuses with RAA had a U-shaped confluence of the ductus arteriosus with the descending aorta on the three vessels and trachea view. The trachea was located between the vessels. In 63,2 % of cases the diagnosis of PDA was made before 22 weeks and in 36,8 % the diagnosis was made after 22 weeks of gestation. In 36 (94,8 %) cases abnormal position of the cross section of the thoracic aorta was identified; however, abnormal position of the axis of the heart were reported only in 4 (10,5 %) out of 38 fetuses.

The article discusses the issues of constructing and reconstructing healthcare settings in Stalingrad in the 1920-1930s. Based on the study of the designs of healthcare settings a number of new architectural trends have been identified. The relationship between healthcare setting design, industrial architecture and a new model for health care has been established.

On the basis of experimental studies we proposed a technology of developing thin-film coated polymer stents for bile duct replacement based on a polymeric substance of polivinillpirrolidon (PVP), saturated with doxorubicin. The developed thin-film coating of an experimental model slows down the bile crystallization process on the surface of a stent sample. We proposed and studied the potential mechanism of formation of a stable PVP-doxorubicin adsorption complex for gradual delivery of doxorubicin into the body and its prolonged action. We analyzed the different types of molecule orientation of doxorubicin in relation to PVP adsorbent (during their interaction), to calculate the main energy characteristics of adsorption processes. We found that the interaction through an oxy group of the doxorubicin molecule is energetically a more favorable option. The proposed technology of applying thin-film drug coating can be introduced as quantum chemical calculations were made and it can become a basis for further research.

A combination of a conservative treatment approach with endoscopic haemostasis is a modern trend in treating acute gastroduodenal bleeding. The article presents an endoscopy software as one of the approaches to the treatment of ulcerative gastroduodenal bleeding.