Vol 13, No 4 (2016)

The article discusses approaches to formation of system availability of narcotic and psychotropic drugs for medical purposes at the present stage. Nearly a half-century policy formation of provision process of essential medicines required special control measures based on prohibitions, restrictions and additional charges led to a complete crisis in health care system. The new strategic orientation of legislative initiatives can greatly facilitate the availability of opioid drugs therapy at all stages of medical care.

The retrospective pharmacoepidemiological study of 564 case histories of patients with an established diagnosis of urolithiasis who were treated in 2013 at the urology hospital of the Volgograd. It is revealed that the most common complication of urolithiasis is pyelonephritis (16.1 %). The main agents of calculous pyelonephritis was E. coli (33,8 %), Kl. pneumoniaе (11,4 %), Enterococcus spp. - (10,3 %) and P. aeruginosa (12,7 %). The greatest sensitivity was observed to amoxicilin - clavulanate, cephalosporins of the third generation and carbapenems, maximal level of resistance to co-trimoxazol, ampicilina, fluoroquinolones.

Sexual motivation and state of spermatogenesis in male rats with experimentally induced alimentary deficiency of magnesium have been studied. An increase in the level of proceptive and reducing of receptive sexual motivation in the hypomagnesemic state. It was noted an increased number of degenerative and immobile forms of spermatozoa, as well as degenerative processes in the epithelium of the seminiferous tubules (inhibition of meiotic activity, growth in the number of tubules with desquamated epithelium) and decreased spermatogenesis index.

The article presents the results of studying the features of phenibutum influence on parameters of blood system circulation and formation of mechanisms for maintaining blood pressure of swimmers aged 10-12 years with disadaptation symptoms and to the information received. For measuring and recording of hemodynamic parameters the tetrapolar rheography method was used. It is shown that a number of age-specific cardiovascular system characteristics in the control group and in the group of placebo were significantly less represented in the literature. At the same time the pumping function of heart in these groups was determined mainly by heart activity and slightly - vascular component. Between TPR and: pump, inotropic function of heart and myocardial contractility and capacity of the left ventricle (respectively) revealed significant negative relationship, which indicated that the predominant role of the heart and small - of the vascular component in the maintenance of blood pressure. At the same time as the disadaptated swimmers who took phenibutum the heart pumping indicators were normalized. This occurred to a greater extent due to the significant increase in the contribution of inotropic component in maintaining blood pressure. The correlation analysis makes possible come to conclusion that the pumping function of heart at the same time kept largely cardiac output, myocardial contractility, heart rate capacity. A significant contribution to the maintenance of optimal blood pressure has brought the capacity of left ventricle. Between the peripheral vascular resistance and: pumping function of heart, myocardial was found negative relationship.

The spectrum and sensitivity to antibiotics of pathogens of bacterial infections in patients admitted to a multidisciplinary hospital are studied. The proposals on optimizing the of antimicrobials drugs usage in the hospital, in accordance with local data on antibiotic resistance are formed.

340 previously obtained CBCT images are studied. Fifty-six (16,5 %) patients had C-shaped canals in mandibular first premolars. Of those patients, 35(62,5 %) had bilateral C-shaped canals, and 21 (37,5 %) had unilateral C-shaped canals. 12 (3,5 %) patients had C-shaped canals in mandibular second premolars. Of those patients, 8 (66,6 %) had bilateral C-shaped canals, and 4 (33,3 %) had unilateral C-shaped canals. The prevalence of C-shaped canals in second mandibular molars were 10,3 % (35 patients). Of those patients, 24 (68,5 %) had bilateral C-shaped canals, and 11 (31,4 %) had unilateral C-shaped canals.

The article is devoted to study the activity of redox enzymes and fosfatnykh in granulomas removed from patients suffering from chronic granulomatous periodontitis. Just studied 67 granulomas, taken after tooth extraction of the relevant indications. It is established that in the early phases of the development of granulomatous periodontitis have seen increased activity of redox, and fosfatnykh glycolytic enzymes in the cells of the epithelium, connective tissue, membrane and fibrous structures of the blood vessel wall granulomas. Exacerbation of chronic granulomatous periodontitis are associated with increased vascular permeability, increased activity of redox, fosfatnykh enzymes in the cell membrane and fibrous structures.

The study was conducted in Volgograd and region among 501 schoolchildren. The mean DAI was 20,0 ± 0,9. Malocclusion was reported among 16 % of the children, 5,6 % had severe malocclusion and handicapping malocclusion. Orthodontic treatment need among 12 and 15-year-old children was 23,8 % and 13,2 % respectively.

In this study we have provided anexperimental assessment of stereometric parameters of different approaches to the abdominal aorta. We have developed a technique of morphometric study and determination of optimal laparoscopic approach to the abdominal aorta, which satisfya current criteria of endoscopic approach.

The analysis of the frequency and composition of the ocular trauma among the adult population of Volgograd and Volgograd region was performed for 2013-2015 years, the level of the exit on disability after severe trauma of organ of vision was determined. The certain socio-economic and medical factors were identified that affect these criteria.

The article assess morphological changes in the vascular wall, and in particular in modeling in the endothelium of L-NAME induced endothelial dysfunction. It is shown that for 7 days of the experience, he starts a pilot injection N-nitro-L-arginine methyl ester (L-NAME), develop changes submicroscopic architectonic endothelial cells, resulting in endothelial dysfunction occurs. The leading element in the development of vascular diseases at the ultrastructural level is mitochondrial failure of endothelial cells. The selected method of L-NAME-induced endothelial pathology is characterized by high reproducibility and adequate results.

The article describes the effectiveness of topical treatment of herpes labialis in children. The results of the study showed that the effectiveness of 5 % acyclovir cream was higher at the beginning of the treatment in the prodromal period. 1 % penciclovir cream (both in the prodromal period and acute stage) was reported to be the most effective. Both drugs reduce the severity of clinical manifestations of herpes labialis; however, they fail to prevent further episodes of herpes labialis.

We performed a comprehensive clinical and laboratory study of 140 patients aged 45-55 with recurrent endometrial hyperplasia. The study of the hormonal status of women revealed ovarian hyperestrogeny thus enabling the surgeon to select the appropriate treatment for endometrial hyperplasia in perimenopausal women.

Differentiating groups of proteins with high potential antigenic activity, which can be apply as diagnostic targets, were selected using in silico genome comparison of pathogenic Burkholderia species. Oligonucleotide primer sets were designed for amplifying and cloning complete DNA sequences of the targets.

We assessed analytical characteristics of immunoturbidimetric determination of cystatin C levels in urine including the detection limit (LoD) and the limit of quantitation (LoQ). We have established the reference values for urinary cystatin C levels which are 0,17-0,25 mg/l.

In this article the results of aprobation of using GIS-technology for eduction of the possible raw material tangles on example of licorice (Glycyrrhiza glabra L.) are provided. Using of modern technologies in resource researches allow considerably reduce the complexity of expeditionary stage and cameral processing data. In our researches we used satellite navigation and space pictures for eduction potential-productive population of licorice in Entre Rios Volga and Achtuba